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Multimeric RGD-Based Strategies for Selective Drug Delivery to Tumor Tissues

• Authors : Cossu, Jordan; Thoreau, Fabien; Boturyn, Didier ...

Subjects: RGD peptide αVβ3 integrin peptide-drug conjugate multimeric RGD; RGD peptide; αVβ3 integrin

• Source: ISSN: 1999-4923 ; Pharmaceutics ; https://hal.science/hal-03986719 ; Pharmaceutics, 2023, 15 (2), pp.525. ⟨10.3390/pharmaceutics15020525⟩.

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Modular chemical construction of IgG-like mono- and bispecific synthetic antibodies (SynAbs)

• Authors : Thoreau, Fabien; Szijj, Peter A; Greene, Michelle K

• Source: Thoreau , F , Szijj , P A , Greene , M K , Rochet , L N C , Thanasi , I A , Blayney , J K , Maruani , A , Baker , J R , Scott , C J & Chudasama , V 2023 , ' Modular

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Enabling the formation of native mAb, Fab′ and Fc-conjugates using a bis-disulfide bridging reagent to achieve tunable payload-to-antibody ratios (PARs)

• Authors : Thoreau, Fabien; Rochet, Léa N. C.; Baker, James R.

Subjects: Chemistry

• Source: Chem Sci

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A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity

• Authors : Rady, Tony; Turelli, Lorenzo; Nothisen, Marc ...

Subjects: [CHIM]Chemical Sciences

• Source: ISSN: 1043-1802.

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Enabling the next steps in cancer immunotherapy: from antibody-based bispecifics to multispecifics, with an evolving role for bioconjugation chemistry

• Authors : Thoreau, Fabien; Chudasama, Vijay; European Commission

Subjects: Biochemistry, Genetics and Molecular Biology (miscellaneous); Molecular Biology; Biochemistry

• Source: RSC Chemical Biology ; volume 3, issue 2, page 140-169 ; ISSN 2633-0679

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A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold

• Authors : Spears, Richard J.; McMahon, Clíona; Shamsabadi, Monika ...

Subjects: Materials Chemistry; Metals and Alloys; Surfaces, Coatings and Films

• Source: Chemical Communications ; volume 58, issue 5, page 645-648 ; ISSN 1359-7345 1364-548X

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Enabling the next steps in cancer immunotherapy: from antibody-based bispecifics to multispecifics, with an evolving role for bioconjugation chemistry

• Authors : Thoreau, Fabien; Chudasama, Vijay

Subjects: Chemistry

• Source: RSC Chem Biol

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Synthesis and Biological Characterization of Monomeric and Tetrameric RGD‐Cryptophycin Conjugates

• Authors : Borbély, Adina; Thoreau, Fabien; Figueras, Eduard ...

Subjects: [CHIM]Chemical Sciences; [CHIM.THER]Chemical Sciences/Medicinal Chemistry; [CHIM.ORGA]Chemical Sciences/Organic chemistry

• Source: ISSN: 0947-6539.

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Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates.

• Authors : Borbély, Adina Noémi; Thoreau, Fabien; Figueras Agustí, Eduard

Subjects: ddc:540

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Chemistry - A European Journal / Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates.

• Authors : Borbély, Adina Noémi; Thoreau, Fabien; Figueras Agustí, Eduard

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