Authors : Zhu J; School of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.; Pharmacy of College, Hunan University of Chinese Medicine, Changsha, China.

Subjects: Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/drug therapy ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/microbiology

Source: PloS one [PLoS One] 2025 Sep 02; Vol. 20 (9), pp. e0331303. Date of Electronic Publication: 2025 Sep 02 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Systems modeling and uncertainty quantification of AMP-activated protein kinase signaling.

Authors : Linden-Santangeli N; Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA, USA.; Zhang J

Subjects: AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/metabolism ; Signal Transduction* ; Systems Biology*/Systems Biology*/Systems Biology*/methods

Source: NPJ systems biology and applications [NPJ Syst Biol Appl] 2025 Oct 14; Vol. 11 (1), pp. 113. Date of Electronic Publication: 2025 Oct 14.Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication

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Academic Journal

Investigating Endogenous Opioids Unravels the Mechanisms Behind Opioid-Induced Constipation, a Mathematical Modeling Approach.

Authors : Coomber C; Institute of Mathematics, Technische Universität Berlin, 10623 Berlin, Germany.; Zuse Institute Berlin, 14195 Berlin, Germany.

Subjects: Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/adverse effects ; Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/metabolism ; Opioid-Induced Constipation*/Opioid-Induced Constipation*/Opioid-Induced Constipation*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 27; Vol. 26 (13). Date of Electronic Publication: 2025 Jun 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Loureirin B Reduces Insulin Resistance and Chronic Inflammation in a Rat Model of Polycystic Ovary Syndrome by Upregulating GPR120 and Activating the LKB1/AMPK Signaling Pathway.

Authors : Wang J; Guangxi Key Laboratory for Applied Fundamental Research of Zhuang Medicine-Key Laboratory Project under Guangxi Health Commission, Guangxi University of Chinese Medicine, Nanning 530001, China.; Guangxi Higher Education Key Laboratory for the Research of Du-Related Diseases in Zhuang Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China.

Subjects: Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/drug therapy ; Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/metabolism ; Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 17; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium:

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Academic Journal

Dual PDE4/10A inhibition restores CREB1 function and enhances neuronal resilience in models of alzheimer's disease.

Authors : Rong X; Suzhou Laboratory of Precision Health and Data Science, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China. .; Institute of Health Data Science, Soochow University, Suzhou, Jiangsu, 215004, China. .

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 Oct 27; Vol. 17 (1), pp. 231. Date of Electronic Publication: 2025 Oct 27.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium:

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Upregulation of GLT-1 Expression Attenuates Neuronal Apoptosis and Cognitive Dysfunction via Inhibiting the CB1-CREB Signaling Pathway in Mice with Traumatic Brain Injury.

Authors : Bu B; Department of Forensic Clinical Medicine, School of Forensic Medicine, China Medical University, Shenyang 110122, China.; Key Laboratory of Forensic Bio-Evidence Science, Shenyang 110122, China.

Subjects: Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/metabolism ; Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/pathology ; Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/Brain Injuries, Traumatic*/genetics

Source: Biomolecules [Biomolecules] 2025 Oct 02; Vol. 15 (10). Date of Electronic Publication: 2025 Oct 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium:

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Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1.

Authors : Elashmony SM; Medical Pharmacology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.; Alhindi Y

Subjects: Vaccinium macrocarpon*/Vaccinium macrocarpon*/Vaccinium macrocarpon*/chemistry ; Metabolic Syndrome*/Metabolic Syndrome*/Metabolic Syndrome*/drug therapy ; Metabolic Syndrome*/Metabolic Syndrome*/Metabolic Syndrome*/metabolism

Source: Scientific reports [Sci Rep] 2025 Sep 15; Vol. 15 (1), pp. 32554. Date of Electronic Publication: 2025 Sep 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Adiponectin Receptor Agonist Ameliorates Synaptic Dysfunction in 3xTg Alzheimer's Disease Mouse Model by Activation of AMPK.

Authors : Bloemer J; Department of Pharmaceutical Sciences, College of Pharmacy, Larkin University, Miami, Florida, USA.; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama, USA.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2025 Sep; Vol. 31 (9), pp. e70616.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium:

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N ε -carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway.

Authors : Liu Z; Department of Cardiology, Shaanxi Provincial People's Hospital, 256 Youyi Xi Rd, Xi'an, 710068, China.; Atherosclerosis Integrated Chinese and Western Medicine Key Research Laboratory, Research Office of Shaanxi Administration of Traditional Chinese Medicine, Xi'an, 710003, China.

Subjects: Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/metabolism ; Autophagy*/Autophagy*/Autophagy*/drug effects ; Plaque, Atherosclerotic*

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Jan 22; Vol. 24 (1), pp. 36. Date of Electronic Publication: 2025 Jan 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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[Expression of Concern] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway.

Authors : Meng HY; Department of Orthopedics, and Key Laboratory of Orthopedic Biomechanics of Hebei Province, Orthopedic Research Institution of Hebei Province, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China.; Shao DC

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Resveratrol*/Resveratrol*/Resveratrol*/pharmacology ; Resveratrol*/Resveratrol*/Resveratrol*/therapeutic use

Source: Molecular medicine reports [Mol Med Rep] 2025 Dec; Vol. 32 (6). Date of Electronic Publication: 2025 Sep 12.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium:

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نتائج البحث

فلترة النتائج

Mechanism of Huanglian Wendan Decoction in ameliorating non-alcoholic fatty liver disease via modulating gut microbiota-mediated metabolic reprogramming and activating the LKB1/AMPK pathway.

Systems modeling and uncertainty quantification of AMP-activated protein kinase signaling.

Investigating Endogenous Opioids Unravels the Mechanisms Behind Opioid-Induced Constipation, a Mathematical Modeling Approach.

Loureirin B Reduces Insulin Resistance and Chronic Inflammation in a Rat Model of Polycystic Ovary Syndrome by Upregulating GPR120 and Activating the LKB1/AMPK Signaling Pathway.

Dual PDE4/10A inhibition restores CREB1 function and enhances neuronal resilience in models of alzheimer's disease.

Upregulation of GLT-1 Expression Attenuates Neuronal Apoptosis and Cognitive Dysfunction via Inhibiting the CB1-CREB Signaling Pathway in Mice with Traumatic Brain Injury.

Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1.

Adiponectin Receptor Agonist Ameliorates Synaptic Dysfunction in 3xTg Alzheimer's Disease Mouse Model by Activation of AMPK.

N ε -carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway.

[Expression of Concern] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway.

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