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The complex effects of miR-146a in the pathogenesis of Alzheimer’s disease

• Authors : Yunfan Long; Jiajia Liu; Yu Wang

Subjects: alzheimer’s disease; amyloid-β; glial cells

• Source: Neural Regeneration Research, Vol 20, Iss 5, Pp 1309-1323 (2025)

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Discovery of Novel Tacrine–Pyrimidone Hybrids as Potent Dual AChE/GSK‑3 Inhibitors for the Treatment of Alzheimer’s Disease

• Authors : Hong Yao (348216); Giuseppe Uras (10860385); Pengfei Zhang (32384)

Subjects: Biochemistry; Cell Biology; Neuroscience

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Docking for Molecules That Bind in a Symmetric Stack with SymDOCK

• Authors : Matthew S. Smith; Ian S. Knight; Rian C. Kormos

Subjects: Biophysics; Biochemistry; Molecular Biology

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Elucidating How Terminal Capping of Tau Hexapeptide PHF6 Modulates the Interactions between PHF6 Fibrils and Membranes

• Authors : Tong Pan; Yuan Tan; Xuewei Dong

Subjects: Biophysics; Biochemistry; Medicine

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Fully Integrated Wearable Biosensor for Multiple In Situ Phosphorylated Tau Protein Detection

• Authors : Xin Sun; Geng Zhong; Yu Zeng

Subjects: Medicine; Molecular Biology; Biotechnology

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Impact of Multiple Phosphorylations on the Tau-R2/Tubulin Interface

• Authors : Jules Marien; Chantal Prévost; Sophie Sacquin-Mora

Subjects: Biophysics; Biochemistry; Cell Biology

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Inclusion of the C‑Terminal Domain in the β‑Sheet Core of Heparin-Fibrillized Three-Repeat Tau Protein Revealed by Solid-State Nuclear Magnetic Resonance Spectroscopy

• Authors : Aurelio J. Dregni (8939669); Harrison K. Wang (10798809); Haifan Wu (1566376)

Subjects: Biophysics; Biochemistry; Medicine

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Misfolding and Self-Assembly Dynamics of Microtubule-Binding Repeats of the Alzheimer-Related Protein Tau

• Authors : Huan He (548057); Yuying Liu (137904); Yunxiang Sun (517700)

Subjects: Biophysics; Biochemistry; Cell Biology

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Molecular Insights into the Differential Effects of Acetylation on the Aggregation of Tau Microtubule-Binding Repeats

• Authors : Yu Zou; Lulu Guan; Jingwang Tan

Subjects: Biophysics; Biochemistry; Biotechnology

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Searching for Structure: Characterizing the Protein Conformational Landscape with Clustering-Based Algorithms

• Authors : Amanda C. Macke; Jacob E. Stump; Maria S. Kelly

Subjects: Biophysics; Biochemistry; Medicine

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Synthesis of 3‑ O ‑Sulfated Heparan Sulfate Oligosaccharides Using 3‑ O ‑Sulfotransferase Isoform 4

• Authors : Jine Li (714818); Guowei Su (2464438); Yongmei Xu (1261962)

Subjects: Biochemistry; Genetics; Plant Biology

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Tau-Targeted Multifunctional Nanoinhibitor for Alzheimer’s Disease

• Authors : Lin Zhu (192179); Linlin Xu (517198); Xiaohui Wu (228851)

Subjects: Biophysics; Biochemistry; Microbiology

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Microtubule Assembly in vitro. Purification of Assembly-Promoting Factors

• Authors : Ana Maria Lennon; Jacques Nunez; Jacques Francon

Subjects: 0301 basic medicine; 0303 health sciences; Macromolecular Substances

• Source: European Journal of Biochemistry. 78:167-174

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Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence.

• Authors : Connolly, J A; Kalnins, V I; Cleveland, D W

• Source: The Journal of cell biology ; volume 76, issue 3, page 781-786 ; ISSN 0021-9525 1540-8140

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Fractionation of brain microtubule-associated proteins. Isolation of two different proteins which stimulate tubulin polymerization in vitro.

• Authors : Herzog W; Weber K

Subjects: Brain Chemistry* ; Glycoproteins* ; Tubulin*

• Source: European journal of biochemistry [Eur J Biochem] 1978 Dec 01; Vol. 92 (1), pp. 1-8.Publisher: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 0107600 Publication Model:

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Thyroid hormones and neurotubule assembly in vitro during brain development.

• Authors : Fellous A; Lennon AM; Francon J

Subjects: Brain/Brain/Brain/*growth & development ; Hypothyroidism/Hypothyroidism/Hypothyroidism/*physiopathology ; Microtubules/Microtubules/Microtubules/*physiology

• Source: European journal of biochemistry [Eur J Biochem] 1979 Nov; Vol. 101 (2), pp. 365-76.Publisher: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 0107600 Publication Model:

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Effects of DNA on microtubule assembly

• Authors : Comisión Interministerial de Ciencia y Tecnología, CICYT (España); Instituto Nacional de Previsión (España); Austrian Science Fund

Subjects: artículo

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Immunofluorescence localization of HeLa cell microtubule-associnted proteins on microtubules

• Authors : Jeannette Chloe Bulinski; Gary G. Borisy; The Pennsylvania State University CiteSeerX Archives

• Source: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/60/69/J_Cell_Biol_1980_Dec_1_87(3)_792-801.tar.gz

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Effects of DNA on Microtubule Assembly

• Authors : Gerhard Wiche; Jesús Avila; Anthony Nasr ...

Subjects: 0301 basic medicine; Microscopy, Electron; 03 medical and health sciences

• Source: Digital.CSIC. Repositorio Institucional del CSICinstnameConsejo Superior de Investigaciones Científicas (CSIC)

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Effects of DNA on Microtubule Assembly.

• Authors : Corces, Victor G.; Manso, Raphael; Javier De La Torre

Subjects: DNA; MICROTUBULES; PROTEIN binding

• Source: European Journal of Biochemistry; 3/15/80, Vol. 105 Issue 1, p7-16, 10p

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Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes

• Authors : David G Drubin; Daniel Caput; Marc W Kirschner ...

• Source: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/9d/62/J_Cell_Biol_1984_Mar_1_98(3)_1090-1097.tar.gz

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Immunoglobulin and other proteins in the cerebrospinal fluid of patients with Alzheimer's disease.

• Authors : Chapel, H M; Esiri, M M; Wilcock, G K

Subjects: Research Article

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Phosphorylation affects the ability of tau protein to promote microtubule assembly.

• Authors : Lindwall, G; Cole, R D

• Source: Journal of Biological Chemistry ; volume 259, issue 8, page 5301-5305 ; ISSN 0021-9258

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Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.

• Authors : Drubin, D G; Caput, D; Kirschner, M W

• Source: The Journal of cell biology ; volume 98, issue 3, page 1090-1097 ; ISSN 0021-9525 1540-8140

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Localization of the tubulin binding site for tau protein

• Authors : SERRANO, Luis; MONTEJO DE GARCINI, Esteban; HERNÁNDEZ, María Angeles

• Source: European Journal of Biochemistry ; volume 153, issue 3, page 595-600 ; ISSN 0014-2956 1432-1033

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Microtubule-associated tau protein function and expression during microtubule-dependent neuronal process extension

• Authors : Drubin, David

Subjects: Proteins; Microtubules; Neurons

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Tau protein function in living cells

• Authors : David G. Drubin; Marc W. Kirschner; The Pennsylvania State University CiteSeerX Archives

• Source: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/94/d4/J_Cell_Biol_1986_Dec_1_103(6)_2739-2746.tar.gz

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One of the Antigenic Determinants of Paired Helical Filaments Is Related to Tau Protein

• Authors : NUKINA, Nobuyuki; IHARA, Yasuo

Subjects: COMMUNICATIONS

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Phosphorylated Tau Protein Is Integrated into Paired Helical Filaments in Alzheimer's Disease

• Authors : IHARA, Yasuo; NUKINA, Nobuyuki; MIURA, Reiko

Subjects: COMMUNICATION

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Tau protein function in living cells.

• Authors : Drubin, D G; Kirschner, M W

• Source: The Journal of cell biology ; volume 103, issue 6, page 2739-2746 ; ISSN 0021-9525 1540-8140

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Separation of the different microtubule-associated tau protein species from bovine brain and their mode II phosphorylation by Ca2+/phospholipid-dependent protein kinase C.

• Authors : Baudier, J; Lee, S H; Cole, R D

• Source: Journal of Biological Chemistry ; volume 262, issue 36, page 17584-17590 ; ISSN 0021-9258

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Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles. Very similar antigenicity of subcortical neuronal pathology in progressive supranuclear palsy and Alzheimer's disease.

• Authors : Probst, A; Langui, Dominique H.; Lautenschlager, C

Subjects: Sciences bio-médicales et agricoles; Aged; 80 and over

• Source: Acta Neuropathologica, 77 (1

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Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells

• Authors : David Drubin; Sumire Kobayashi; Doug Kellogg ...

• Source: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/76/21/J_Cell_Biol_1988_May_1_106(5)_1583-1591.tar.gz

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Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells.

• Authors : Drubin, D; Kobayashi, S; Kellogg, D

• Source: The Journal of cell biology ; volume 106, issue 5, page 1583-1591 ; ISSN 0021-9525 1540-8140

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Senile plaque neurites fail to demonstrate anti-paired helical filament and anti-microtubule-associated protein-tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex.

• Authors : Probst, A; Anderton, Brian; Brion, Jean Pierre

Subjects: Sciences bio-médicales et agricoles; Adult; Aged

• Source: Acta Neuropathologica, 77 (4

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Altered levels of microtubule proteins in brains of Alzheimer's disease patients

• Authors : Comisión Asesora de Investigación Científica y Técnica, CAICYT (España); Instituto de Salud Carlos III; Nieto, Amelia

Subjects: artículo

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The specific binding of the microtubule-associated protein 2 (MAP2) to the outer membrane of rat brain mitochondria

• Authors : Lindén, M; Nelson, B D; Leterrier, J F

• Source: Biochemical Journal ; volume 261, issue 1, page 167-173 ; ISSN 0264-6021 1470-8728

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Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation

• Authors : T. Hagestedt; B. Lichtenberg; H. Wille ...

Subjects: protein kinase; MAP; microtub

• Source: http://www.mpasmb-hamburg.mpg.de/mand-pdf/Tau Protein_Hagestedt_Lichtenberg_Wille_EMMandelkow_EMandelkow.pdf.

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Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family.

• Authors : Himmler, A

• Source: Molecular and Cellular Biology ; volume 9, issue 4, page 1389-1396 ; ISSN 0270-7306 1098-5549

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Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

• Authors : Goedert, M.; Spillantini, M. G.; Potier, M. C.

• Source: The EMBO Journal ; volume 8, issue 2, page 393-399 ; ISSN 0261-4189

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Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation.

• Authors : Hagestedt, T; Lichtenberg, B; Wille, H

• Source: The Journal of cell biology ; volume 109, issue 4, page 1643-1651 ; ISSN 0021-9525 1540-8140

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Tau in situ hybridization in normal and alzheimer brain: Localization in the somatodendritic compartment

• Authors : Kosik, Kenneth S.; Crandall, James E.; Mufson, Elliott J.

• Source: Translational Neuroscience

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Tau protein: An update on structure and function

• Authors : Lee, Gloria

• Source: Cell Motility ; volume 15, issue 4, page 199-203 ; ISSN 0886-1544

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Characterization of tau protein present in microtubules and paired helical filaments of Alzheimer's disease patient's brain

• Authors : Comisión Asesora de Investigación Científica y Técnica, CAICYT (España); Instituto de Salud Carlos III; Boehringer Ingelheim Fonds

Subjects: artículo

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Expression of Tau protein and Tau mRNA in the cerebellum during axonal outgrowth.

• Authors : Couchie, D; Legay, F; Guilleminot, J

Subjects: Sciences bio-médicales et agricoles; Aging; Animals

• Source: Experimental Brain Research, 82 (3

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Protein TAU variants present in paired helical filaments (PHFs) of alzheimer brains

• Authors : Gache, Y.; Ricolfi, F.; Guilleminot, J.

• Source: FEBS Letters ; volume 272, issue 1-2, page 65-68 ; ISSN 0014-5793 1873-3468

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Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

• Authors : Goedert, M.; Jakes, R.

• Source: The EMBO Journal ; volume 9, issue 13, page 4225-4230 ; ISSN 0261-4189

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Tau Proteins and Neurofibrillary Degeneration

• Authors : Goedert, M.; Spillantini, M. G.; Crowther, R. A.

• Source: Brain Pathology ; volume 1, issue 4, page 279-286 ; ISSN 1015-6305 1750-3639

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A novel brain‐specific 25 kDa protein (p25) is phosphorylated by a Ser/Thr‐Pro kinase (TPK II) from tau protein kinase fractions

• Authors : Takahashi, Miho; Tomizawa, Kayoko; Ishiguro, Koichi

• Source: FEBS Letters ; volume 289, issue 1, page 37-43 ; ISSN 0014-5793 1873-3468

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Tau protein binds to microtubules through a flexible array of distributed weak sites. Z Cell Biol

• Authors : Karena Butner; Marc W. Kirschner; The Pennsylvania State University CiteSeerX Archives

• Source: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/14/c0/J_Cell_Biol_1991_Nov_1_115(3)_717-730.tar.gz

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