نتائج البحث

Investigation of the pharmacological activity of the tetrapeptide HAEЕ, zinc, and human serum albumin in a transgenic mouse model with tau protein overexpression (P301S)

• Authors : Veronika S. Shmigerova; Yulia V. Stepenko; Alexandra A. Kurbatova

Subjects: tauopathy; haee-zn-hsa complex pharmaceutical composition; Therapeutics. Pharmacology

• Source: Research Results in Pharmacology, Vol 11, Iss 1, Pp 49-57 (2025)

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Regulation of tau protein by circCwc27: shared pathogenic mechanisms in type 2 diabetes mellitus and Alzheimer’s disease

• Authors : Keying Fang; Bin Jiao; Lu Shen

Subjects: circCwc27; Alzheimer’s disease; Type 2 diabetes mellitus

• Source: Brain Informatics, Vol 12, Iss 1, Pp 1-13 (2025)

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Obstructive sleep apnea exacerbates cognitive impairment after stroke and the diagnostic value of serum BDNF and Tau protein

• Authors : ZHAO Dongmei, CAO Feihu, WANG Libo, HUANG Jun, DU Yuxin, LIU Qian

Subjects: obstructive sleep apnea; stroke; cognitive impairment

• Source: Jichu yixue yu linchuang, Vol 45, Iss 9, Pp 1195-1199 (2025)

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Geometry based prediction of tau protein sites and motifs associated with misfolding and aggregation

• Authors : Sugiyama, Masumi; Kosik, Kenneth S; Panagiotou, Eleni

Subjects: Biochemistry and Cell Biology; Biological Sciences; Neurodegenerative

• Source: Scientific Reports. 15(1)

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Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life

• Authors : Latina, Valentina; De Introna, Margherita; Malerba, Francesca

Subjects: Preclinical animal model; Research; Tau protein

• Source: Acta Neuropathol CommunActa Neuropathologica Communications, Vol 13, Iss 1, Pp 1-31 (2025)

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Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Promote Its Binding with Stable Microtubules

• Authors : Sosuke Yagishita; Megumi Shibata; Akiko Furuno

Subjects: 0301 basic medicine; 0303 health sciences; phosphorylation

• Source: Neurol IntNeurology International, Vol 16, Iss 3, Pp 653-662 (2024)

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Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study

• Authors : Schoonhoven, Deborah N.; Coomans, Emma M.; Millán, Ana P. ...

Subjects: Medical and Health Sciences; Basic Medicine; Neurosciences

• Source: Brain. 146(10):4040-4054

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Neurons ensheathed by perineuronal nets are prone to hyperphosphorylation of tau protein in the hibernating Syrian hamster brain.

• Authors : Berrouschot, Valerie¹ (AUTHOR); Sonntag, Mandy^1,2 (AUTHOR); Reimann, Katja¹ (AUTHOR)

• Source: Scientific Reports. 9/1/2025, Vol. 15 Issue 1, p1-18. 18p.

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Study on the role of N6-methyl adenosine in arsenic induced tau protein phosphorylation.

• Authors : LONG Ke-yan¹; XIONG Wen-xiao¹; ZHENG Qun-hui¹

• Source: Modern Preventive Medicine. 2025, Vol. 52 Issue 3, p533-540. 8p.

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Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions

• Authors : Paul PS; Rathnam M; Khalili A

Subjects: tau protein; plga nanoparticles; tau pathology

• Source: International Journal of Nanomedicine, Vol 20, Pp 1999-2019 (2025)

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Relationship of C-reactive protein and Tau protein serum levels during ischemic stroke

• Authors : Joanna Bielewicz; Beata Daniluk; Michał J. Sekuła

Subjects: c-reactive protein; tau protein; ischemic stroke

• Source: Studia Medyczne, Vol 41, Iss 2, Pp 103-109 (2025)

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Picomolar Detection of Tau Protein Using 1D Photonic Crystal Biochips for Alzheimer's Disease Diagnosis

• Authors : Alberto Sinibaldi; Francesco Chiavaioli; Agostino Occhicone

Subjects: 1D photonic crystals; Alzheimer's disease; biophotonic platform

• Source: Advanced Sensor Research, Vol 4, Iss 5, Pp n/a-n/a (2025)

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GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial

• Authors : Humaloja, Jaana; Lähde, Marika; Ashton, Nicholas J. ...

Subjects: Medical and Health Sciences; Clinical Medicine; Anesthesiology and Intensive Care

• Source: Resuscitation. 170:141-149

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Effect of temperature changes on the expression of cancer stem cell protein CD-44 and TAU protein in AMGM-5 cancer cell line: An immunocytochemistry study

• Authors : Zaynab Saad Abdulghany

• Source: International Journal of Medical Biochemistry. :21-26

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Effects of CREB and miR-132-3p on aluminum-induced abnormal phosphorylation of tau protein in rat hippocampus

• Authors : Wenjie XIAO; Xu XU; Minmin LEI

Subjects: aluminum; mir-132-3p; cyclic amp response element binding protein

• Source: 环境与职业医学, Vol 41, Iss 11, Pp 1270-1276 (2024)

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Evaluation of Tau Protein in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants

• Source: Phase 0 Exploratory Study of [18F]MNI-1020 (Also Known as [18F]JNJ-64326067) as an Imaging Marker for Tau Protein in the Brain of Subjects

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High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease

• Authors : Arastoo, Mohammad; Penny, Lewis Kirk; Lofthouse, Richard Andrew ...

Subjects: Monoclonal antibody; Supplementary Information; Neurosciences. Biological psychiatry. Neuropsychiatry

• Source: Alzheimers Res TherAlzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)

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Overview of the Molecular Modalities and Signaling Pathways Intersecting with β-Amyloid and Tau Protein in Alzheimer’s Disease

• Authors : Ahmed M. Elshazly; Melanie M. Sinanian; Diaaeldin M. Elimam

Subjects: 0301 basic medicine; 0303 health sciences; 03 medical and health sciences

• Source: Neuroglia, Vol 4, Iss 3, Pp 191-208 (2023)

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Tau Protein Binding Modes in Alzheimer's Disease for Cationic Luminescent Ligands

• Authors : Todarwal, Y; Gustafsson, C; Minh, NNT

• Source: JOURNAL OF PHYSICAL CHEMISTRY B. 125(42):11628-11636

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Exploring tau protein and amyloid-beta propagation: a sensitivity analysis of mathematical models based on biological data

• Authors : Corti, Mattia

Subjects: Mathematics - Numerical Analysis; Quantitative Biology - Quantitative Methods

• Source: Brain Multiphysics 431. 100098 (2024)

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Effects of subchronic benzo [a] pyrene toxicity on tau protein phosphorylation and mild cognitive dysfunction in HAPOE4 genotype mice.

• Authors : GAO Xu-tao¹; SHI Jing-ya¹; WANG Si-yu¹

• Source: Modern Preventive Medicine. 2025, Vol. 52 Issue 6, p1118-1124. 7p.

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Inflammatory cytokines, oxidative stress, and tau protein impairment in cognitive functioning in patients with diabetes mellitus

• Authors : Harpreet Kour; Sanjay Mishra; Aishwarya Hattiholi

Subjects: cognitive impairment; diabetes mellitus; inflammatory cytokines

• Source: Muller Journal of Medical Sciences and Research, Vol 15, Iss 1, Pp 40-47 (2024)

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Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice

• Authors : Alejandro Martín-Ávila; Swananda R. Modak; Hameetha B. Rajamohamedsait

Subjects: CP: Neuroscience; CP: Cell biology; Biology (General)

• Source: Cell Reports, Vol 44, Iss 10, Pp 116291- (2025)

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Advances in blood‐based phosphorylated tau protein biomarkers and their detection technology for Alzheimer's disease

• Authors : Shiyuan Fu; Qiaoping Zheng; Beihui Xu

Subjects: Alzheimer's disease; biomarker; blood

• Source: View, Vol 6, Iss 4, Pp n/a-n/a (2025)

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Tau Protein Biosensors in the Diagnosis of Neurodegenerative Diseases

• Authors : Jafar Sadeghzadeh; Parviz Shahabi; Mehdi Farhoudi

Subjects: 0301 basic medicine; 0303 health sciences; 03 medical and health sciences

• Source: Adv Pharm BullAdvanced Pharmaceutical Bulletin, Vol 13, Iss 3, Pp 502-511 (2023)

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The novel role of Kallistatin in linking metabolic syndromes and cognitive memory deterioration by inducing amyloid-β plaques accumulation and tau protein hyperphosphorylation

• Authors : Weiwei Qi; Yanlan Long; Ziming Li

Subjects: Alzheimer's disease; Kallistatin; Aβ42

• Source: eLife, Vol 13 (2025)

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Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau protein

• Authors : E. M. Kondaurova; A. A. Komarova; T. V. Ilchibaeva

Subjects: alzheimer’s disease; tau protein; amisulpride

• Source: Вавиловский журнал генетики и селекции, Vol 28, Iss 4, Pp 398-406 (2024)

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Tau protein mediates the association between frailty and postoperative delirium: a machine learning model incorporating cerebrospinal fluid biomarkers

• Authors : Yizhi Liang; Chuanlin Mu; Wenjie Kong

Subjects: machine learning; postoperative delirium; cerebrospinal fluid

• Source: Frontiers in Neurology, Vol 16 (2025)

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Corrigendum to 'Electrochemical modulation of tau protein phosphorylation levels with biomimetic polyaniline membranes' [Sensing and Bio-Sensing Research, Volume 48, June 2025, 100805]

• Authors : Shang-Chi Chien; Chia-Hsuan Chang; Hung-Ju Wang

Subjects: Engineering (General). Civil engineering (General); TA1-2040

• Source: Sensing and Bio-Sensing Research, Vol 49, Iss , Pp 100832- (2025)

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A single-domain antibody for the detection of pathological Tau protein in the early stages of oligomerization

• Authors : de Leiris, Nicolas; Perret, Pascale; Lombardi, Charlotte ...

Subjects: 0301 basic medicine; [SDV.BIO]Life Sciences [q-bio]/Biotechnology; SdAb

• Source: J Transl MedJournal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

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Electrochemical modulation of tau protein phosphorylation levels with biomimetic polyaniline membranes

• Authors : Shang-Chi Chien; Chia-Hsuan Chang; Hung-Ju Wang

Subjects: Phosphorylated tau; Electrochemistry; Dephosphorylation

• Source: Sensing and Bio-Sensing Research, Vol 48, Iss , Pp 100805- (2025)

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Study on the Molecular Mechanism of Baicalin Phosphorylation of Tau Protein Content in a Cell Model of Intervention Cognitive Impairment

• Authors : Li J; Zhao C; Guan D

Subjects: baicalein; mild cognitive impairment ; sh-sy5y; pi3k-akt signaling pathway; Neurosciences. Biological psychiatry. Neuropsychiatry; RC321-571

• Source: Neuropsychiatric Disease and Treatment, Vol 21, Pp 309-322 (2025)

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Clinical Study of [18F] PM-PBB3 PET Imaging of Tau Protein in Neurodegenerative Diseases

• Source: Clinical Study of [18F] PM-PBB3 PET Imaging of Tau Protein in Neurodegenerative Diseases

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[125I]INFT: Synthesis and Evaluation of a New Imaging Agent for Tau Protein in Post-Mortem Human Alzheimer’s Disease Brain

• Authors : Limpengco, Roz R; Liang, Christopher; Sandhu, Yasmin K

Subjects: Dementia; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Brain Disorders

• Source: Molecules. 28(15)

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The Discovery of Putative Small Molecules via Ligand-based Pharmacophore Modelling Targeting Human Tau Protein for an Effective Treatment of Parkinson’s Disease

• Authors : Yahaya Sani Najib; Yusuf Oloruntoyin Ayipo; Waleed Abdullah Ahmad Alananzeh

Subjects: 0301 basic medicine; 0303 health sciences; 03 medical and health sciences

• Source: Malaysian Journal of Medicine and Health Sciences. 19:83-94

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Mutations in Tau Protein Promote Aggregation by Favoring Extended Conformations.

• Authors : Pounot, Kevin; Piersson, Clara; Goring, Andrew

• Source: JACS Au. 4(1)

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The Role of Traditional Chinese Medicine Natural Products in β-Amyloid Deposition and Tau Protein Hyperphosphorylation in Alzheimer’s Disease

• Authors : Yan H; Feng L; Li M

Subjects: alzheimer's disease; β-amyloid deposition; tau-protein hyperphosphorylation

• Source: Drug Design, Development and Therapy, Vol 17, Pp 3295-3323 (2023)

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Substance Abuse and Cognitive Decline: The Critical Role of Tau Protein as a Potential Biomarker.

• Authors : Rebolledo-Pérez L; Departamento de Biología Molecular y Genética, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44100, Mexico.; Hernández-Bello J

Subjects: tau Proteins*/tau Proteins*/tau Proteins*/metabolism ; Substance-Related Disorders*/Substance-Related Disorders*/Substance-Related Disorders*/metabolism ; Substance-Related Disorders*/Substance-Related Disorders*/Substance-Related Disorders*/complications

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 07; Vol. 26 (15). Date of Electronic Publication: 2025 Aug 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Structures of Oligomeric States of Tau Protein, Amyloid-β, α-Synuclein and Prion Protein Implicated in Alzheimer's Disease, Parkinson's Disease and Prionopathies.

• Authors : Cehlar, Ondrej¹ (AUTHOR) ; Njemoga, Stefana¹ (AUTHOR); Horvath, Marian¹ (AUTHOR)

• Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p13049. 31p.

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Tau Protein and β-Amyloid Associated with Neurodegeneration in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis (EAE), a Mouse Model of Multiple Sclerosis

• Authors : Grażyna Pyka-Fościak; Ewa Jasek-Gajda; Bożena Wójcik

Subjects: tau protein; p-tau protein; β-amyloid

• Source: Biomedicines, Vol 12, Iss 12, p 2770 (2024)

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Trans- and cis-phosphorylated tau protein: new pieces of the puzzle in the development of neurofibrillary tangles in post-ischemic brain neurodegeneration of the Alzheimer’s disease-like type

• Source: International Journal of Molecular Sciences. 25(6):1-12

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Tau Protein Accumulation Trajectory-Based Brain Age Prediction in the Alzheimer's Disease Continuum.

• Authors : Wang, Min¹ (AUTHOR); Wei, Min² (AUTHOR); Wang, Luyao¹ (AUTHOR)

• Source: Brain Sciences (2076-3425). Jun2024, Vol. 14 Issue 6, p575. 11p.

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The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts

• Authors : Fan Yong; Yang Yongkai; Lin Kunzhe

Subjects: cerebral microinfarcts; aqp4; tau protein

• Source: Open Medicine, Vol 18, Iss 1, Pp 1569-79 (2023)

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Serum tau protein elevation in migraine: a cross-sectional case–control study

• Authors : Lucas Hendrik Overeem; Bianca Raffaelli; Robert Fleischmann

Subjects: Headache; CSF; Trigeminal Nerve

• Source: The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-11 (2023)

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Investigation of Bax and Phospho-Tau Protein Expression in Preeclampsia Placenta

• Authors : Seval KAYA; Fırat AŞIR; Hayat AYAZ

Subjects: apoptosis; bax; phospho-tau

• Source: Volume: 20, Issue: 3 477-484Journal of Harran University Medical FacultyHarran Üniversitesi Tıp Fakültesi Dergisi

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Enhanced fluorescence detection of tau protein using photonic crystal-based biochips: a novel tool for Alzheimer's disease diagnostics

• Authors : Sinibaldi, Alberto; Chiavaioli, Francesco; Occhicone, Agostino ...

Subjects: Alzheimer; tau protein; biosensor

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Neuron-specific enolase and Tau protein as biomarkers for sepsis-associated delirium: a cross-sectional pilot study

• Authors : Agnes Araújo Sardinha Pinto; Maira Mello de Carvalho; Juliana Bahia Santos

Subjects: Biomarkers; Delirium; Emergency medicine

• Source: Einstein (São Paulo), Vol 23 (2025)

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Study on the Molecular Mechanism of Baicalin Phosphorylation of Tau Protein Content in a Cell Model of Intervention Cognitive Impairment

• Authors : Li,Juncheng; Zhao,Canbin; Guan,Donghui

Subjects: Neuropsychiatric Disease and Treatment; Original Research; info:eu-repo/semantics/article

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Investigating the impact of sorghum on tau protein phosphorylation and mitochondrial dysfunction modulation in Alzheimer’s disease: An in vitro study

• Authors : Rezaee, Nasim; Hone, Eugene; Sohrabi, Hamid

Subjects: Alzheimer’s disease; amyloid beta protein; human tau

• Source: Research outputs 2022 to 2026

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Role of Tau Protein in Neurodegenerative Diseases and Development of Its Targeted Drugs: A Literature Review.

• Authors : Yang, Jiakai^1,2 (AUTHOR) ; Zhi, Weijia² (AUTHOR) ; Wang, Lifeng^1,2 (AUTHOR)

• Source: Molecules. Jun2024, Vol. 29 Issue 12, p2812. 23p.

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