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  • 1-10 ل  958 نتائج ل ""Progranulins""

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Academic Journal

Macrophage-Specific Progranulin Deficiency Prevents Diet-Induced Obesity through the Inhibition of Hypothalamic and Adipose Tissue Inflammation.

  • Authors : Lee CH; Department of Biomedical Science, Hallym University, Chuncheon, Korea.; Park CB

Subjects: Progranulins*/Progranulins*/Progranulins*/genetics ; Progranulins*/Progranulins*/Progranulins*/deficiency ; Obesity*/Obesity*/Obesity*/metabolism

  • Source: Diabetes & metabolism journal [Diabetes Metab J] 2025 Jul; Vol. 49 (4), pp. 784-797. Date of Electronic Publication: 2025 Mar 11.Publisher: Korean Diabetes Association Country of Publication: Korea (South) NLM ID: 101556588 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Development of AL101 (GSK4527226), a progranulin-elevating monoclonal antibody, as a potential treatment for Alzheimer's disease.

  • Authors : Budda B; Alector, Inc, 131 Oyster Point Blvd, #600, South San Francisco, CA, 94080, USA. .; Mitra A

Subjects: Progranulins*/Progranulins*/Progranulins*/metabolism ; Progranulins*/Progranulins*/Progranulins*/blood ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 Jul 25; Vol. 17 (1), pp. 174. Date of Electronic Publication: 2025 Jul 25.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency.

  • Authors : Nader WO; Killion Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.; Brown KS

Subjects: Progranulins*/Progranulins*/Progranulins*/genetics ; Progranulins*/Progranulins*/Progranulins*/deficiency ; Progranulins*/Progranulins*/Progranulins*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jul 19; Vol. 15 (1), pp. 26217. Date of Electronic Publication: 2025 Jul 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.

  • Authors : Clelland CD; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA. .; Memory & Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA. .

Subjects: c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/genetics ; c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/metabolism ; Progranulins*/Progranulins*/Progranulins*/genetics

  • Source: Communications biology [Commun Biol] 2025 Jul 01; Vol. 8 (1), pp. 971. Date of Electronic Publication: 2025 Jul 01.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The role of endolysosomal progranulin and TMEM106B in neurodegenerative diseases.

  • Authors : Takahashi H; Cellular Neuroscience, Neurodegeneration, Repair, Departments of Neurology and of Neuroscience, Yale University School of Medicine, New Haven, CT, 06536, USA.; Strittmatter SM

Subjects: Progranulins*/Progranulins*/Progranulins*/metabolism ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Jul 26; Vol. 20 (1), pp. 86. Date of Electronic Publication: 2025 Jul 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Academic Journal

Amniotic and cervical fluids progranulin levels in pregnancies complicated by spontaneous preterm delivery with respect to intra-amniotic complications-a retrospective cohort study.

  • Authors : Soucek O; Department of Clinical Immunology and Allergology University Hospital Hradec Kralove, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.; Kacerovsky M

Subjects: Amniotic Fluid*/Amniotic Fluid*/Amniotic Fluid*/metabolism ; Progranulins*/Progranulins*/Progranulins*/metabolism ; Fetal Membranes, Premature Rupture*/Fetal Membranes, Premature Rupture*/Fetal Membranes, Premature Rupture*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jul 11; Vol. 15 (1), pp. 25054. Date of Electronic Publication: 2025 Jul 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models.

  • Authors : Yang C; Department of Molecular Biology and Genetics, 345 Weill Hall, Ithaca, NY, 14853, USA.; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, 14853, USA.

Subjects: Progranulins*/Progranulins*/Progranulins*/deficiency ; Progranulins*/Progranulins*/Progranulins*/genetics ; Progranulins*/Progranulins*/Progranulins*/metabolism

  • Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Jun 17; Vol. 20 (1), pp. 72. Date of Electronic Publication: 2025 Jun 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Academic Journal

PGRN as an emerging regulator of lipid metabolism in neurodegenerative diseases.

  • Authors : Shi Y; School of Basic Medical Sciences, Fudan University, Shanghai, China.; Hou W

Subjects: Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/metabolism ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/genetics ; Progranulins*/Progranulins*/Progranulins*/metabolism

  • Source: Communications biology [Commun Biol] 2025 Jun 02; Vol. 8 (1), pp. 844. Date of Electronic Publication: 2025 Jun 02.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The antioxidant stress effect of granulin precursor in vitiligo.

  • Authors : Guo H; Department of Dermatology, Third Xiangya Hospital, Central South University, No.138 Tongzipo Road, Yuelu, Changsha, 410013, China.; Chen J

Subjects: Vitiligo*/Vitiligo*/Vitiligo*/metabolism ; Vitiligo*/Vitiligo*/Vitiligo*/pathology ; Vitiligo*/Vitiligo*/Vitiligo*/genetics

  • Source: Scientific reports [Sci Rep] 2025 May 25; Vol. 15 (1), pp. 18189. Date of Electronic Publication: 2025 May 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Progranulin's Protective Mechanisms and Therapeutic Potential in Cardiovascular Disease.

  • Authors : Qiao G; Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China.; Nucleic Acid Medicine of Luzhou Key Laboratory, Central Nervous System Drug Key Laboratory of Sichuan Province, Southwest Medical University, Luzhou 646000, China.

Subjects: Progranulins*/Progranulins*/Progranulins*/metabolism ; Progranulins*/Progranulins*/Progranulins*/therapeutic use ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/metabolism

  • Source: Cells [Cells] 2025 May 22; Vol. 14 (11). Date of Electronic Publication: 2025 May 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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  • 1-10 ل  958 نتائج ل ""Progranulins""