نتائج البحث

Progranulin Plays a Protective Role in Pneumococcal Meningitis by Inhibiting Pyroptosis.

• Authors : Wang, Jingyao^1,2,3 (AUTHOR); Kang, Lihua^1,2,4 (AUTHOR); Xu, Wenlong² (AUTHOR)

• Source: Immunity, Inflammation & Disease. Feb2025, Vol. 13 Issue 2, p1-10. 10p.

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Elevated plasma progranulin levels in the acute phase are correlated with recovery of left ventricular function in the chronic phase in patients with acute myocardial infarction.

• Authors : Minatoguchi, Shingo¹ (AUTHOR); Satake, Atsushi² (AUTHOR); Murase, Hirotaka² (AUTHOR)

Subjects: *Coronary artery stenosis; *Myocardial infarction; *Enzyme-linked immunosorbent assay

• Source: PLoS ONE. 11/8/2024, Vol. 19 Issue 11, p1-12. 12p.

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Progranulin, sICAM-1, and sVCAM-1 May Predict an Increased Risk for Ventricular Arrhythmias in Patients with Systemic Sclerosis.

• Authors : Sebestyén, Veronika^1,2 (AUTHOR) ; Ratku, Balázs^1,3 (AUTHOR) ; Ujvárosy, Dóra¹ (AUTHOR)

Subjects: *Ventricular arrhythmia; *Systemic scleroderma; *Progranulin

• Source: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 13, p7380. 13p.

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sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models

• Authors : Cha Yang; Huan Du; Gwang Bin Lee

Subjects: Progranulin; Inflammation; Lysosome

• Source: Molecular Neurodegeneration, Vol 20, Iss 1, Pp 1-25 (2025)

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Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.

• Authors : Clelland, Claire Dudley^1,2 (AUTHOR) ; Fan, Li³ (AUTHOR); Saloner, Rowan² (AUTHOR)

• Source: Communications Biology. 7/1/2025, Vol. 8 Issue 1, p1-14. 14p.

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Circulating Progranulin: A Promising Novel Diagnostic and Prognostic Biomarker in Canine Oncology.

• Authors : Kim, Keon^1,2,3 (AUTHOR); Kim, Yeong Jun^2,3,4 (AUTHOR); Choi, Chang Hyeon^1,2,3 (AUTHOR)

• Source: Animals (2076-2615). Jun2025, Vol. 15 Issue 11, p1605. 15p.

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Microglial progranulin differently regulates hypothalamic lysosomal function in lean and obese conditions via cleavage-dependent mechanisms

• Authors : Chae Beom Park; Chan Hee Lee; Gil Myoung Kang

Subjects: Progranulin; Granulin; Hypothalamus

• Source: Journal of Neuroinflammation, Vol 22, Iss 1, Pp 1-14 (2025)

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Investigation on the effectiveness of progranulin as a novel predictive biomarker for allergic disorders

• Authors : Nisreen Waleed Mustafa; Zaid Nabeel Elia; Abeer Mansour Abdel Rasool

Subjects: biomarkers; progranulin; respiratory allergy

• Source: Journal of Advanced Biotechnology and Experimental Therapeutics, Vol 8, Iss 1, Pp 116-124 (2025)

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Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) (PROCLAIM)

• Authors : Eli Lilly and Company

• Source: A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of LY3884963 in Patients With Fronto-Temporal Dementia With

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A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors.

• Authors : Swift, Imogen J.^1,2 (AUTHOR); Rademakers, Rosa^3,4,5 (AUTHOR); Finch, NiCole³ (AUTHOR)

• Source: Alzheimer's Research & Therapy. 3/28/2024, Vol. 16 Issue 1, p1-13. 13p.

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