نتائج البحث

Assessing data size requirements for training generalizable sequence-based TCR specificity models via pan-allelic MHC-I point-mutation ligandome evaluation.

• Authors : Delaunay A; InstaDeep Ltd, 5 Merchant Sq, London, UK. .; McGibbon M

Subjects: Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/genetics ; Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/metabolism ; Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/Receptors, Antigen, T-Cell*/immunology

• Source: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42384. Date of Electronic Publication: 2025 Nov 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

CTCF Point Mutation at R567 Disrupts Mouse Heart Development via 3D Genome Rearrangement and Transcription Dysregulation.

• Authors : Ren H; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China.; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

Subjects: CCCTC-Binding Factor*/CCCTC-Binding Factor*/CCCTC-Binding Factor*/genetics ; CCCTC-Binding Factor*/CCCTC-Binding Factor*/CCCTC-Binding Factor*/metabolism ; Heart*/Heart*/Heart*/embryology

• Source: Cell proliferation [Cell Prolif] 2025 Apr; Vol. 58 (4), pp. e13783. Date of Electronic Publication: 2024 Dec 16.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

تفاصيل العنوان

IMPI: An Interface for Low-Frequency Point Mutation Identification Exemplified on Resistance Mutations in Chronic Myeloid Leukemia.

• Authors : Vetter, Julia^1,2 ; Burghofer, Jonathan³; Malli, Theodora³

• Source: BioMedInformatics. Jun2024, Vol. 4 Issue 2, p1289-1307. 19p.

تفاصيل العنوان

A semidominant point mutation of Mediator tail subunit MED5b in Arabidopsis leads to altered enrichment of H3K27me3 and reduced expression of targets of MYC2.

• Authors : Long J; Department of Biochemistry, Purdue University, West Lafayette, IN 47906, USA.; Sliger S

Subjects: Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/metabolism ; Arabidopsis Proteins*/Arabidopsis Proteins*/Arabidopsis Proteins*/genetics

• Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2025 Mar 18; Vol. 15 (3).Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN:

تفاصيل العنوان

Mis-splicing drives loss of function of p53E224D point mutation.

• Authors : Lock IC; Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America.; Leisenring NH

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Point Mutation*

• Source: PloS one [PLoS One] 2025 Mar 05; Vol. 20 (3), pp. e0318856. Date of Electronic Publication: 2025 Mar 05 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Tepotinib for the Treatment of Lung Adenocarcinoma Harboring MET Y1003N Point Mutation: A Case Report.

• Authors : Umeda Y; Department of Respiratory Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan.; Kimura S

Subjects: Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/drug therapy ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/genetics ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/pathology

• Source: Thoracic cancer [Thorac Cancer] 2025 Jan; Vol. 16 (2), pp. e15508. Date of Electronic Publication: 2024 Dec 15.Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print-Electronic Cited Medium: Internet

تفاصيل العنوان

Improvement of thermal stability of oyster (Crassostrea gigas) ferritin by point mutation

• Authors : Li, Han; Tan, Xiaoyi; Xia, Xiaoyu

Subjects: Ferritin; Point mutation; Structure

• Source: Food Chemistry. 346

تفاصيل العنوان

15q13.2q13.3 microdeletion syndrome with congenital stationary night blindness due to compound deletion and a missense point mutation in TRPM1 gene

• Authors : Justyna Pietrasik; Marlena Młynek; Agata Wiśniewska

Subjects: 15q13.3 microdeletion syndrome; trpm1 gene; congenital stationary night blindness.

• Source: Pediatria Polska, Vol 100, Iss 4, Pp 394-397 (2025)

تفاصيل العنوان

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models.

• Authors : Ong, Jun Kai^1,2 (AUTHOR); Bhunia, Sayari^1,3,4 (AUTHOR); Hilbert, Beate¹ (AUTHOR)

• Source: Scientific Reports. 2/20/2026, Vol. 16 Issue 1, p1-19. 19p.

تفاصيل العنوان

Assessing the reliability of point mutation as data augmentation for deep learning with genomic data.

• Authors : Lee H; Korea University, Seoul, South Korea.; Ozbulak U

Subjects: Genomics*/Genomics*/Genomics*/methods ; Deep Learning* ; Point Mutation*

• Source: BMC bioinformatics [BMC Bioinformatics] 2024 Apr 30; Vol. 25 (1), pp. 170. Date of Electronic Publication: 2024 Apr 30.Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105

تفاصيل العنوان