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A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) (CheckMate 8HW)

• Authors : Ono Pharmaceutical Co. Ltd

• Source: A Phase 3 Randomized Clinical Trial of Nivolumab Alone, Nivolumab in Combination With Ipilimumab, or Investigator's Choice Chemotherapy in Participants With

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Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

• Source: An Open-label, Multi-center Phase I/Ib Dose Finding and Expansion Study of HRO761 as Single Agent and in Combinations in Patients With Microsatellite

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Safety and Efficacy of Canagliflozin in Patients With Metastatic High Microsatellite Instability (MSI-H) Colorectal Cancer

• Authors : Xuelei Ma MD, Deputy Director (Medical) of the Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University; Associate Director of the Stem Cell Research and Translational Research Laboratory; PhD Supervisor

• Source: Safety and Efficacy of Canagliflozin in Patients With Metastatic High Microsatellite Instability (MSI-H) Colorectal Cancer: a Phase I

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Primary cutaneous lymphoma is a microsatellite stable tumor: An analysis of microsatellite instability.

• Authors : Maeda-Otsuka S; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Mijiddorj MT

Subjects: Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/genetics ; Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/pathology ; Microsatellite Instability* Subcutaneous panniculitis-like T-cell lymphoma

• Source: Drug discoveries & therapeutics [Drug Discov Ther] 2025 Jul 04; Vol. 19 (3), pp. 212-213. Date of Electronic Publication: 2025 Jun 25.Publisher: Shandong University China-Japan Cooperation Center for Drug Discovery & Screen Country of Publication: Japan NLM ID: 101493809 Publication Model:

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Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

• Source: A Phase 2, Multicenter, Multi Arm, Study to Evaluate MK-1308A (Co-formulated Quavonlimab (MK-1308)/Pembrolizumab) Versus Other Treatments in Participants With

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Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

• Authors : Yugui Lian, The First Affiliated Hospital of Zhengzhou University

• Source: Eight Vs Four Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced

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Deficient Mismatch Repair and Microsatellite Instability in Solid Tumors.

• Authors : Awosika JA; Gastrointestinal Malignancies Section, Thoracic & GI Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Gulley JL

Subjects: Microsatellite Instability* ; DNA Mismatch Repair*/DNA Mismatch Repair*/DNA Mismatch Repair*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 06; Vol. 26 (9). Date of Electronic Publication: 2025 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Microsatellite instability in colorectal cancer.

• Authors : Chen XY; Department of Pathology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.; Li HX

Subjects: Microsatellite Instability* ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

• Source: Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2025 Apr 01; Vol. 68 (2), pp. 255-260. Date of Electronic Publication: 2024 Jun 20.Publisher: Medknow Country of Publication: India NLM ID: 7605904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-5130

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Microsatellite Instability Status and Programmed Death Cell Ligand 1 Expression in Serous Ovarian Tumors.

• Authors : TEOMAN, Gizem¹ (AUTHOR); ERCİN, Mustafa Emre² (AUTHOR)

• Source: Bezmialem Science. 2025, Vol. 13 Issue 3, p1-5. 5p.

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The effect of Entamoeba histolytica lectin antigen and microRNA-643 on the development of microsatellite instability (MSI) in colorectal adenocarcinoma.

• Authors : Haghighi L; Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box: 14115-131, Tehran, Iran.; Dalimi A

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Microsatellite Instability*

• Source: BMC cancer [BMC Cancer] 2025 Apr 10; Vol. 25 (1), pp. 663. Date of Electronic Publication: 2025 Apr 10.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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