نتائج البحث

Polystyrene nanoplastics trigger pyroptosis in dopaminergic neurons through TSC2/TFEB-mediated disruption of autophagosome-lysosome fusion in Parkinson's disease.

• Authors : Liang, Xiaomei^1,2 (AUTHOR); Zeng, Yaqi³ (AUTHOR); Zhang, Piao^1,2 (AUTHOR)

• Source: Journal of Translational Medicine. 6/5/2025, Vol. 23 Issue 1, p1-25. 25p.

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Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation.

• Authors : Kim, Dohyun¹ (AUTHOR); Yang, Gyeongseok¹ (AUTHOR); Lim, Chaelyeong¹ (AUTHOR)

• Source: Advanced Science. 7/10/2025, Vol. 12 Issue 26, p1-13. 13p.

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Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury

• Authors : Peng-Fei Dong; Tian-Bin Liu; Kai Chen

Subjects: Cadmium; transcription factor EB; Acute kidney injury

• Source: Journal of Advanced Research, Vol 72, Iss , Pp 653-669 (2025)

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First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy–lysosome pathway

• Authors : Ye Zhong; Jing Xu; Huiying Cao

Subjects: Protein degradation; Hydrophobic tags; ATG101

• Source: Acta Pharmaceutica Sinica B, Vol 15, Iss 5, Pp 2612-2624 (2025)

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Mitochondria-Lysosome Contact Sites: Emerging Players in Cellular Homeostasis and Disease.

• Authors : Rizzollo, Francesca^1,2 (AUTHOR); Agostinis, Patrizia^1,2 (AUTHOR)

• Source: Contact (25152564). 3/18/2025, p1-9. 9p.

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Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms

• Authors : Kaur, Namrita; Carlsson, Sven R.; Lystad, Alf Håkon

Subjects: Atg8; atg8ylation; autophagy

• Source: Frontiers in Cell and Developmental Biology. 13

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Application and Suggestions of Morpholine Ring as a Lysosome Targeting Group.

• Authors : Liu, Xuelian¹ (AUTHOR); Zhang, Ximeng¹ (AUTHOR); Han, Yinghong¹ (AUTHOR)

• Source: Chemistry (2624-8549). Jun2025, Vol. 7 Issue 3, p82. 27p.

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Multi-omics analysis reveals lysosome-associated molecular subtype characterization and prognostic modeling system in lung adenocarcinoma.

• Authors : Zhanmei Wang¹; Yan Wang²; Jinxiang Wang³

• Source: Journal of Cancer. 2025, Vol. 16 Issue 6, p1794-1813. 20p.

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V‐ATPase Disassembly at the Yeast Lysosome‐Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging.

• Authors : Hashmi, Fiza¹ (AUTHOR); Kane, Patricia M.¹ (AUTHOR)

• Source: Aging Cell. May2025, Vol. 24 Issue 5, p1-13. 13p.

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The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion

• Authors : Jing Yang; Zhunan Li; Aicong Li

Subjects: Mycobacterium tuberculosis; bovine Coronin-1A; WD repeat domain

• Source: Veterinary Research, Vol 56, Iss 1, Pp 1-14 (2025)

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