نتائج البحث

Novel Azaborine-Based Inhibitors of Histone Deacetylases (HDACs).

• Authors : Behringer M; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Haardtring 100, 64295 Darmstadt, Germany.; Schweipert M

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemical synthesis

• Source: Molecules (Basel, Switzerland) [Molecules] 2025 Oct 08; Vol. 30 (19). Date of Electronic Publication: 2025 Oct 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells.

• Authors : Lewis CA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America.; University of North Carolina HIV Cure Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America.

Subjects: CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/virology ; CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/metabolism ; HIV-1*/HIV-1*/HIV-1*/physiology

• Source: PLoS pathogens [PLoS Pathog] 2025 Sep 03; Vol. 21 (9), pp. e1013073. Date of Electronic Publication: 2025 Sep 03 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Epigenomics Nutritional Insights of Crocus sativus L.: Computational Analysis of Bioactive Molecules Targeting DNA Methyltransferases and Histone Deacetylases.

• Authors : Piergentili A; Institute for Neuroscience and Medicine (INM-9), Forschungszentrum Jülich, Wilhelm-Johnen-Straße, 52428 Jülich, Germany.; Department of Neurology, University Hospital Aachen, RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.

Subjects: Crocus*/Crocus*/Crocus*/chemistry ; Epigenomics*/Epigenomics*/Epigenomics*/methods ; DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/antagonists & inhibitors

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 05; Vol. 26 (15). Date of Electronic Publication: 2025 Aug 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Inhibition of histone deacetylases 3 attenuates imiquimod-induced psoriatic dermatitis via targeting cGAS-STING signaling in keratinocytes.

• Authors : Zeng C; Department of Microbiology and Immunology, School of Medicine, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, 510630, China. .; Wen X

Subjects: Imiquimod*/Imiquimod*/Imiquimod*/adverse effects ; Psoriasis*/Psoriasis*/Psoriasis*/pathology ; Psoriasis*/Psoriasis*/Psoriasis*/drug therapy

• Source: Journal of translational medicine [J Transl Med] 2025 Jun 02; Vol. 23 (1), pp. 609. Date of Electronic Publication: 2025 Jun 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Integrative Analysis of Histone Deacetylases Reveals the Potential Role and Prognostic Value of HDAC7 in Hepatocellular Carcinoma

• Authors : Changjiang Yang; Zhenze Yu; Ranran Wang

• Source: Journal of Cancer. 16:3389-3402

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A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

• Authors : Eunice K. Poon; Ligong Liu; Kai‐Chen Wu

Subjects: Histone Deacetylase Inhibitors; Male; Lipopolysaccharides

• Source: British Journal of Pharmacology. 181:4804-4821

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Histone acetylation regulated by histone deacetylases during spermatogenesis.

• Authors : Ou X; Department of Occupational Health and Toxicology, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang, P. R. China.; Yang J

Subjects: Spermatogenesis*/Spermatogenesis*/Spermatogenesis*/physiology ; Histone Deacetylases*/Histone Deacetylases*/Histone Deacetylases*/metabolism ; Histones*/Histones*/Histones*/metabolism

• Source: Andrology [Andrology] 2025 May; Vol. 13 (4), pp. 706-717. Date of Electronic Publication: 2024 Aug 12.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Synthesis and biological evaluation of ortho -phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases.

• Authors : Hsu KC; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemical synthesis ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2406025. Date of Electronic Publication: 2024 Sep 24.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The study of Histone Deacetylases Immunoexpression in relation to Regulating Vascular Endothelial Growth Factor (VEGF) Implicated in Malignant Progression of Colorectal cancer

• Authors : Yasir B. Qaddoori; Ahmed S.K. AL‑Khafaji; Basim M. Khashman

• Source: Iraqi Journal of Science. :1861-1875

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Histone Deacetylases in Neurodegenerative Diseases and Their Potential Role as Therapeutic Targets: Shedding Light on Astrocytes.

• Authors : Pinheiro, Pedro de Sena Murteira¹ (AUTHOR); Diniz, Luan Pereira² (AUTHOR); Franco, Lucas S.^1,3 (AUTHOR)

• Source: Pharmaceuticals (14248247). Oct2025, Vol. 18 Issue 10, p1471. 25p.

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