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Phylogenetics And Molecular Docking Studies On Glycogen Phosphorylase Inhibitors As Anti-Diabetic Agents.

• Authors : Rushmitha, Samoju¹; Kommoju, Vallayyachari²; Sudhakar, Godi³

• Source: Frontiers in Health Informatics. 2024, Vol. 13 Issue 8, p3810-3820. 11p.

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Synthesis, In Silico and Kinetics Evaluation of N -(β-d-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N -(β-d-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as Glycogen Phosphorylase Inhibitors.

• Authors : Homolya, Levente¹ (AUTHOR) ; Mathomes, Rachel T.² (AUTHOR); Varga, Luca³ (AUTHOR)

Subjects: *Glycogen phosphorylase; *Imidazoles; *Amides

• Source: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 9, p4591. 21p.

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Physicochemical and Spectroscopic Characterization of Glycogen and Glycogen Phosphorylase b Complexes.

• Authors : Karakousi, Pandora¹ (AUTHOR) ; Karayianni, Maria^1,2 (AUTHOR) ; Chrysina, Evangelia D.¹ (AUTHOR)

• Source: Polysaccharides (2673-4176). Sep2024, Vol. 5 Issue 3, p225-240. 16p.

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A Novel 5-Chloro- N -Phenyl-1 H -Indole-2-carboxamide Derivative as a Glycogen Phosphorylase Inhibitor: Evaluating the Long-Term Drug Effects on Muscle Function for the First Time.

• Authors : Zhao, Yifan¹ (AUTHOR) ; Yan, Zhiwei¹ (AUTHOR) ; Li, Shuai¹ (AUTHOR)

Subjects: *Glycogen phosphorylase; *Muscle metabolism; *Myocardial ischemia

• Source: Molecules. Sep2024, Vol. 29 Issue 18, p4448. 8p.

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Brain-Type Glycogen Phosphorylase (PYGB) in the Pathologies of Diseases: A Systematic Review.

• Authors : Yang, Caiting¹ (AUTHOR) ; Wang, Haojun¹ (AUTHOR) ; Shao, Miaomiao² (AUTHOR)

• Source: Cells (2073-4409). Feb2024, Vol. 13 Issue 3, p289. 22p.

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The importance of muscle glycogen phosphorylase in glial cells function.

• Authors : Llavero, Francisco¹ ; Zugaza, José L.^1,2,3

Subjects: *Glycogen phosphorylase; *Neuroglia; *Cell physiology

• Source: Biochemical Society Transactions. Jun2024, Vol. 52 Issue 3, p1266-1274. 9p.

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A single dose of glycogen phosphorylase inhibitor improves cognitive functions of aged mice and affects the concentrations of metabolites in the brain.

• Authors : Pudełko-Malik N; Department of Biochemistry, Molecular Biology and Biotechnology, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, Wroclaw, 50-370, Poland.; Drulis-Fajdasz D

Subjects: Cognition*/Cognition*/Cognition*/drug effects ; Glycogen Phosphorylase*/Glycogen Phosphorylase*/Glycogen Phosphorylase*/metabolism ; Glycogen Phosphorylase*/Glycogen Phosphorylase*/Glycogen Phosphorylase*/antagonists & inhibitors

• Source: Scientific reports [Sci Rep] 2024 Oct 15; Vol. 14 (1), pp. 24123. Date of Electronic Publication: 2024 Oct 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Glycogen phosphorylase inhibition improves cognitive function of aged mice.

• Authors : Drulis‐Fajdasz, Dominika¹ (AUTHOR); Krzystyniak, Adam² (AUTHOR); Puścian, Alicja³ (AUTHOR)

• Source: Aging Cell. Sep2023, Vol. 22 Issue 9, p1-18. 18p.

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Evidence for the Quercetin Binding Site of Glycogen Phosphorylase as a Target for Liver-Isoform-Selective Inhibitors against Glioblastoma: Investigation of Flavanols Epigallocatechin Gallate and Epigallocatechin

• Authors : Alexopoulos, Serafeim; McGawley, Megan; Mathews, Roshini

Subjects: Kinetics; Binding Sites; Liver

• Source: J Agric Food ChemJournal of agricultural and food chemistry 72(43), 24070-24081 (2024). doi:10.1021/acs.jafc.4c06920

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Design and Synthesis of 3-(β-d-Glucopyranosyl)-4-amino/4-guanidino Pyrazole Derivatives and Analysis of Their Glycogen Phosphorylase Inhibitory Potential.

• Authors : Kun, Sándor¹ (AUTHOR); Mathomes, Rachel T.² (AUTHOR); Docsa, Tibor³ (AUTHOR)

Subjects: *Glycogen phosphorylase; *Pyrazole derivatives; *Hydrogen bonding interactions

• Source: Molecules. Apr2023, Vol. 28 Issue 7, p3005. 19p.

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