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Complement Factor B Deficiency Is Dispensable for Female Fertility but Affects Microbiome Diversity and Complement Activity.

• Authors : Sunamoto M; Laboratory of Regulatory Biology, Department of Life Sciences, School of Agriculture, Meiji University, 1-1-1 Higashimita, Kawasaki 214-8571, Japan.; Morohoshi K

Subjects: Complement Factor B*/Complement Factor B*/Complement Factor B*/genetics ; Complement Factor B*/Complement Factor B*/Complement Factor B*/metabolism ; Complement Factor B*/Complement Factor B*/Complement Factor B*/deficiency

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Feb 06; Vol. 26 (3). Date of Electronic Publication: 2025 Feb 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The Crosstalk Between NETs and the Complement Cascade: An Overview in Nephrological Autoimmune Disease.

• Authors : Kajana, Xhuliana¹ (AUTHOR); Caridi, Gianluca¹ (AUTHOR); Bruschi, Maurizio¹ (AUTHOR)

Subjects: *COMPLEMENT activation; *HUMORAL immunity; *COMPLEMENT (Immunology)

• Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2789. 14p.

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Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study.

• Authors : Pinzon-Hoyos, Nicole¹ (AUTHOR); Li, Yibo¹ (AUTHOR); McGee, Monnie² (AUTHOR)

• Source: Scientific Reports. 2/11/2025, Vol. 15 Issue 1, p1-13. 13p.

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The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway.

• Authors : Turner NA; Department of Bioengineering, Rice University, Houston, TX, USA. .; Moake JL

Subjects: Complement Factor H*/Complement Factor H*/Complement Factor H*/metabolism ; Complement Pathway, Alternative* ; Complement Factor I*/Complement Factor I*/Complement Factor I*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Mar 29; Vol. 15 (1), pp. 10883. Date of Electronic Publication: 2025 Mar 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Complement C3a promotes the formation of osteoclasts by inhibiting Sirt1 to activate the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma.

• Authors : Jiang, Fengjuan^1,2,3 (AUTHOR); Zhang, Yunhe^1,2,3 (AUTHOR); Peng, Fengping^1,2,3 (AUTHOR)

• Source: Journal of Translational Medicine. 3/16/2025, Vol. 23 Issue 1, p1-20. 20p.

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A bipartite bacterial virulence factor targets the complement system and neutrophil activation.

• Authors : Kurniyati, Kurni¹ (AUTHOR); Clark, Nicholas D² (AUTHOR); Wang, Hongxia¹ (AUTHOR)

Subjects: *MEDICAL sciences; *CLINICAL immunology; *COMPLEMENT activation

• Source: EMBO Journal. Feb2025, Vol. 44 Issue 4, p1154-1184. 31p.

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Targeted Complement Treatments in Glomerulopathies: A Comprehensive Review.

• Authors : Gentile, Micaela¹ (AUTHOR) ; Manenti, Lucio² (AUTHOR)

• Source: Journal of Clinical Medicine. Feb2025, Vol. 14 Issue 3, p702. 17p.

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Evidence of a Lytic Pathway in an Invertebrate Complement System: Identification of a Terminal Complement Complex Gene in a Colonial Tunicate and Its Evolutionary Implications.

• Authors : Ballarin, Loriano¹ (AUTHOR) ; Peronato, Anna¹ (AUTHOR); Malagoli, Davide^2,3 (AUTHOR)

Subjects: *COMPLEMENT activation; *COMPLEMENT (Immunology); *COLONIAL animals (Marine invertebrates)

• Source: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p11995. 20p.

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Complement activity and autophagy are dysregulated in the lungs of patients with nonresolvable COVID-19 requiring lung transplantation.

• Authors : Shivshankar, Pooja^1,2,3 (AUTHOR) ; Mueller-Ortiz, Stacey L.² (AUTHOR); Domozhirov, Aleksey Y.² (AUTHOR)

• Source: Respiratory Research. 2/27/2025, Vol. 26 Issue 1, p1-18. 18p.

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Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC.

• Authors : Magda, Michal¹ (AUTHOR); Boschloo, Wendy¹ (AUTHOR); Bettoni, Serena¹ (AUTHOR)

• Source: Journal of Innate Immunity. Jan2025, Vol. 17 Issue 1, p112-125. 14p. 5 Illustrations.

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