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Comparative proteomic analysis of metronidazole-sensitive and resistant Trichomonas vaginalis suggests a novel mode of metronidazole action and resistance

• Authors : Anna-Lena Mayr; Ana Paunkov; Karin Hummel

Subjects: Trichomonas Vaginalis Drug Effects; Trichomonas Vaginalis Genetics; Metronidazole Pharmacology

• Source: International Journal for Parasitology - Drugs and Drug Resistance ; issn:2211-3207

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Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1

• Authors : Tulloch, Lindsay B; Tinti, Michele; Wall, Richard J

Subjects: NADPH-ferrihemoprotein Reductase - metabolism - genetics; Drug resistance; Amphotericin B - pharmacology

• Source: Tulloch , L B , Tinti , M , Wall , R J , Weidt , S K , Corpas-Lopez , V , Dey , G , Smith , T K , Fairlamb , A H , Barrett , M P & Wyllie , S 2024 , ' Sterol 14-alpha demethylase (CYP51) activity in

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The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni

• Authors : Gouveia, M; Brindley, P; Azevedo, C ...

Subjects: Anthelmintic; Biomolecules; N-acetylcysteine

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Development of an automated image analysis protocol for quantification of intracellular forms of Leishmania spp

• Authors : Gomes-Alves, AG; Maia, AF; Cruz, T ...

Subjects: Amphotericin B / pharmacology; Animals; Antiprotozoal Agents / pharmacology

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In Silico Discovery of a Substituted 6-Methoxy-quinalidine with Leishmanicidal Activity in Leishmania infantum

• Authors : Stevanovic, S; Perdih, A; Sencanski, M ...

Subjects: Antiprotozoal Agents / chemistry; Antiprotozoal Agents / pharmacology; Catalytic Domain / drug effects

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Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

• Authors : Faria, J; Loureiro, I; Santarém, N ...

Subjects: Aldose-Ketose Isomerases/genetics; Aldose-Ketose Isomerases/metabolism; Amino Acid Sequence

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Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.

• Authors : Brettmann, E.A.; Shaik, J.S.; Zangger, H.

Subjects: Animals; Antiprotozoal Agents/chemistry; Antiprotozoal Agents/metabolism

• Source: Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 43, pp. 11998-12005

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Naegleria gruberi metabolism.

• Authors : Opperdoes, Fred R; De Jonckheere, Johan; Tielens, Aloysius G M ...

Subjects: Antiprotozoal Agents - pharmacology; Humans; Naegleria - drug effects

• Source: International Journal for Parasitology, Vol. 41, no. 9, p. 915-24 (2011)

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Determinacion in vitro de la susceptibilidad a la nitazoxanida de cuatro aislados de giardia duodenalis obtenidos de diferentes huespedes.

• Authors : MARTHA PONCE MACOTELA; JOSEFINA GÓMEZ GARDUÑO; ANGELICA GONZALEZ MACIEL

Subjects: info:eu-repo/classification/cti/3; Antiprotozoarios - Farmacología; Parásitos intestinales - Veterinaria

• Source: Rev Invest Clin 53(1):41-45

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Development of a semi-automated image-based high-throughput drug screening system.

• Authors : Eren, R.O.; Kopelyanskiy, D.; Moreau, D.

Subjects: Animals; Antiprotozoal Agents/pharmacology; Automation

• Source: Frontiers in bioscience, vol. 10, pp. 242-253

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