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Academic Journal

Suppressor protein plasma levels and inflammatory indices in colorectal cancer patients.

Authors : Chigvinadze N; Department of Genetics, Ivane Javakhishvili Tbilisi State University, Tbilisi, 0186, Georgia.; Vl. Bakhutashvili Institute of Medical Biotechnology, Tbilisi State Medical University, Tbilisi, 0159, Georgia.

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/blood ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

Source: BMC cancer [BMC Cancer] 2025 Apr 25; Vol. 25 (1), pp. 774. Date of Electronic Publication: 2025 Apr 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Combined KRAS and TP53 mutation in patients with colorectal cancer enhance chemoresistance to promote postoperative recurrence and metastasis.

Authors : Tang Y; Department of General Surgery, The Third Hospital of MianYang, Sichuan Mental Health Center, MianYang, 621000, China.; Fan Y

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

Source: BMC cancer [BMC Cancer] 2024 Sep 17; Vol. 24 (1), pp. 1155. Date of Electronic Publication: 2024 Sep 17.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Effects of KRAS, STK11, KEAP1, and TP53 mutations on the clinical outcomes of immune checkpoint inhibitors among patients with lung adenocarcinoma.

Authors : Liang Y; Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Aichi, Japan.; Maeda O

Subjects: Kelch-Like ECH-Associated Protein 1*/Kelch-Like ECH-Associated Protein 1*/Kelch-Like ECH-Associated Protein 1*/genetics ; AMP-Activated Protein Kinase Kinases* ; Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/genetics

Source: PloS one [PLoS One] 2024 Jul 22; Vol. 19 (7), pp. e0307580. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A Rare Case of Primary Hepatic Undifferentiated Pleomorphic Sarcoma: Exploring Cancer-related Gene Mutations.

Authors : Suzuki H; Division of Gastroenterology, Department of Medicine, Kurume University, School of Medicine, Japan.; Fukuda M

Subjects: Mutation*/Mutation*/Mutation*/genetics ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/genetics ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/diagnosis

Source: Internal medicine (Tokyo, Japan) [Intern Med] 2025 Jun 01; Vol. 64 (11), pp. 1653-1658. Date of Electronic Publication: 2024 Nov 08.Publisher: Japanese Society of Internal Medicine Country of Publication: Japan NLM ID: 9204241 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Impact of Oncogenic Changes in p53 and KRAS on Macropinocytosis and Ferroptosis in Colon Cancer Cells and Anticancer Efficacy of Niclosamide with Differential Effects on These Two Processes.

Authors : Nguyen NT; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Sennoune SR

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Pinocytosis*/Pinocytosis*/Pinocytosis*/drug effects

Source: Cells [Cells] 2024 May 30; Vol. 13 (11). Date of Electronic Publication: 2024 May 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Gene Therapy Targeting p53 and KRAS for Colorectal Cancer Treatment: A Myth or the Way Forward?

Authors : Hasbullah HH; Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.; Musa M

Subjects: Mutation*; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*therapy ; Genetic Therapy/Genetic Therapy/Genetic Therapy/*methods

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 03; Vol. 22 (21). Date of Electronic Publication: 2021 Nov 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

YTHDF1 Promotes Cyclin B1 Translation through m 6 A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation.

Authors : Lou X; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, State Key Laboratory of Molecular Oncology, Department of Clinical Laboratory, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.; Ning J

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*genetics ; Adenosine/Adenosine/Adenosine/*analogs & derivatives ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*genetics

Source: Cells [Cells] 2021 Jul 02; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation.

Authors : Schwartz M; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

Subjects: CCCTC-Binding Factor/CCCTC-Binding Factor/CCCTC-Binding Factor/*metabolism ; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*metabolism ; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*metabolism

Source: Communications biology [Commun Biol] 2020 Nov 25; Vol. 3 (1), pp. 696. Date of Electronic Publication: 2020 Nov 25.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy.

Authors : Hendricks A; Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. .; Present Address: Department of General Surgery, University Medicine Rostock, Schillingallee 35, 18507, Rostock, Germany. .

Subjects: Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/*blood ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*blood IFL protocol

Source: BMC medical genetics [BMC Med Genet] 2020 Jan 03; Vol. 21 (1), pp. 3. Date of Electronic Publication: 2020 Jan 03.Publisher: BioMed Central Country of Publication: England NLM ID: 100968552 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2350

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Academic Journal

Co-mutations of TP53 and KRAS serve as potential biomarkers for immune checkpoint blockade in squamous-cell non-small cell lung cancer: a case report.

Authors : Fang C; Departments of Oncology, the Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.; Zhang C

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*diagnosis ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*diagnosis ; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*genetics

Source: BMC medical genomics [BMC Med Genomics] 2019 Oct 16; Vol. 12 (1), pp. 136. Date of Electronic Publication: 2019 Oct 16.Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794

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نتائج البحث

فلترة النتائج

Suppressor protein plasma levels and inflammatory indices in colorectal cancer patients.

Combined KRAS and TP53 mutation in patients with colorectal cancer enhance chemoresistance to promote postoperative recurrence and metastasis.

Effects of KRAS, STK11, KEAP1, and TP53 mutations on the clinical outcomes of immune checkpoint inhibitors among patients with lung adenocarcinoma.

A Rare Case of Primary Hepatic Undifferentiated Pleomorphic Sarcoma: Exploring Cancer-related Gene Mutations.

Impact of Oncogenic Changes in p53 and KRAS on Macropinocytosis and Ferroptosis in Colon Cancer Cells and Anticancer Efficacy of Niclosamide with Differential Effects on These Two Processes.

Gene Therapy Targeting p53 and KRAS for Colorectal Cancer Treatment: A Myth or the Way Forward?

YTHDF1 Promotes Cyclin B1 Translation through m 6 A Modulation and Contributes to the Poor Prognosis of Lung Adenocarcinoma with KRAS/TP53 Co-Mutation.

Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation.

Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy.

Co-mutations of TP53 and KRAS serve as potential biomarkers for immune checkpoint blockade in squamous-cell non-small cell lung cancer: a case report.

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