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Academic Journal

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway.

Authors : Tung NTC; Department of Trauma and Orthopaedic Surgery, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam. .; Department of Orthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan. .

Subjects: Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/metabolism ; Cell Differentiation* ; Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/metabolism

Source: Scientific reports [Sci Rep] 2025 Jul 15; Vol. 15 (1), pp. 25505. Date of Electronic Publication: 2025 Jul 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibitory Potential of the Drimane Sesquiterpenoids Isotadeonal and Polygodial in the NF-kB Pathway.

Authors : Marín V; Laboratory of Natural Products & Drug Discovery, Center CEBIM, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco 4780000, Chile.; Villegas C

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/antagonists & inhibitors ; Sesquiterpenes*/Sesquiterpenes*/Sesquiterpenes*/pharmacology

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Mar 31; Vol. 30 (7). Date of Electronic Publication: 2025 Mar 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy.

Authors : Xia B; School of Forensic Medicine, Guizhou Medical University, Guiyang, 550004, Guizhou, China. .; Liang J

Subjects: Autophagy* ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Lactoferrin*/Lactoferrin*/Lactoferrin*/metabolism

Source: Scientific reports [Sci Rep] 2025 Mar 27; Vol. 15 (1), pp. 10585. Date of Electronic Publication: 2025 Mar 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways.

Authors : Mianesaz H; Department of Human Genetics, Faculty of Medicine, University of Debrecen, Debrecen H-4032, Hungary.; Göczi L

Subjects: Receptors, Calcitriol*/Receptors, Calcitriol*/Receptors, Calcitriol*/metabolism ; Receptors, Calcitriol*/Receptors, Calcitriol*/Receptors, Calcitriol*/genetics ; Receptors, Calcitriol*/Receptors, Calcitriol*/Receptors, Calcitriol*/agonists

Source: Nucleic acids research [Nucleic Acids Res] 2025 Mar 20; Vol. 53 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The Organogermanium Compound 3-(trihydroxygermyl)propanoic Acid Exerts Anti-Inflammatory Effects via Adenosine-NR4A2 Signaling.

Authors : Azumi J; Research Division, Asai Germanium Research Institute Co., Ltd., Suzuranoka 3-131, Hakodate 042-0958, Hokkaido, Japan.; Takeda T

Subjects: Adenosine*/Adenosine*/Adenosine*/metabolism ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Mar 09; Vol. 26 (6). Date of Electronic Publication: 2025 Mar 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling.

Authors : Fischer TD; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. .; Bunker EN

Subjects: Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/genetics ; Signal Transduction*

Source: The EMBO journal [EMBO J] 2025 Jan; Vol. 44 (1), pp. 141-165. Date of Electronic Publication: 2024 Nov 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nuclear Factor-κB Signaling Regulates the Nociceptin Receptor but Not Nociceptin Itself.

Authors : Zhang L; Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.; Department for BioMedical Research, University of Bern, 3008 Bern, Switzerland.

Subjects: Nociceptin Receptor* ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Nociceptin*

Source: Cells [Cells] 2024 Dec 20; Vol. 13 (24). Date of Electronic Publication: 2024 Dec 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Prolonged Extracorporeal Circulation Leads to Inflammation and Higher Expression of Mediators of Vascular Permeability Through Activation of STAT3 Signaling Pathway in Macrophages.

Authors : Luecht J; Department of Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum der Charité, 13353 Berlin, Germany.; Pauli C

Subjects: STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; Signal Transduction* ; Macrophages*/Macrophages*/Macrophages*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 19; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Effects of the oxLDL/β2GPI/anti-β2GPI Complex on Macrophage Autophagy and its Mechanism.

Authors : Wu Q; Department of Transfusion Medicine, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.; Zhang G

Subjects: Lipoproteins, LDL*/Lipoproteins, LDL*/Lipoproteins, LDL*/metabolism ; Autophagy*/Autophagy*/Autophagy*/immunology ; beta 2-Glycoprotein I*/beta 2-Glycoprotein I*/beta 2-Glycoprotein I*/immunology

Source: Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Nov; Vol. 12 (11), pp. e70058.Publisher: John Wiley and Sons Ltd Country of Publication: England NLM ID: 101635460 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Spinster homolog 2/S1P signaling ameliorates macrophage inflammatory response to bacterial infections by balancing PGE 2 production.

Authors : Fang C; Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.; Ren P

Subjects: Signal Transduction* ; Dinoprostone*/Dinoprostone*/Dinoprostone*/metabolism ; Sphingosine*/Sphingosine*/Sphingosine*/analogs & derivatives

Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 30; Vol. 22 (1), pp. 463. Date of Electronic Publication: 2024 Sep 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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نتائج البحث

فلترة النتائج

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway.

Inhibitory Potential of the Drimane Sesquiterpenoids Isotadeonal and Polygodial in the NF-kB Pathway.

Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy.

Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways.

The Organogermanium Compound 3-(trihydroxygermyl)propanoic Acid Exerts Anti-Inflammatory Effects via Adenosine-NR4A2 Signaling.

STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling.

Nuclear Factor-κB Signaling Regulates the Nociceptin Receptor but Not Nociceptin Itself.

Prolonged Extracorporeal Circulation Leads to Inflammation and Higher Expression of Mediators of Vascular Permeability Through Activation of STAT3 Signaling Pathway in Macrophages.

The Effects of the oxLDL/β2GPI/anti-β2GPI Complex on Macrophage Autophagy and its Mechanism.

Spinster homolog 2/S1P signaling ameliorates macrophage inflammatory response to bacterial infections by balancing PGE 2 production.

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