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Academic Journal

Distinct late-stage osteoarthritis profiles identified through NF-κB, TNF-α, and TGF-β-driven synovial inflammation and pain.

  • Authors : Semenistaja S; Department of Doctoral Studies, Rīga Stradiņš University, Dzirciema St. 16, Riga, LV-1007, Latvia.; Sokolovska L

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/Tumor Necrosis Factor-alpha*/metabolism ; Transforming Growth Factor beta*/Transforming Growth Factor beta*/Transforming Growth Factor beta*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Aug 19; Vol. 15 (1), pp. 30288. Date of Electronic Publication: 2025 Aug 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dual Roles of Prostaglandin E2 (PGE2) in Bone Remodeling and Pain Management: Bridging the Gap in Osteoarthritis Research.

  • Authors : Zhang Y; School of Stomatology, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China.; Wu W

Subjects: Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/drug therapy ; Bone Remodeling*/Bone Remodeling*/Bone Remodeling*/physiology

  • Source: Mediators of inflammation [Mediators Inflamm] 2025 Jul 26; Vol. 2025, pp. 8882429. Date of Electronic Publication: 2025 Jul 26 (Print Publication: 2025).Publisher: Wiley Country of Publication: United States NLM ID: 9209001 Publication Model: eCollection Cited Medium: Internet ISSN: 1466-1861

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Academic Journal

Comparative Pain Expression and Its Association to Intestinal Microbiota Through the MI-RAT© Osteoarthritis Model Induced in LOU/C/Jall and Sprague-Dawley Aged Rats.

  • Authors : Frézier M; Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Université de Montréal, St.-Hyacinthe, QC J2S 2M2, Canada.; Otis C

Subjects: Gastrointestinal Microbiome* ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/microbiology ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 08; Vol. 26 (16). Date of Electronic Publication: 2025 Aug 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation.

  • Authors : Alad M; Department of Surgical and Interventional Sciences, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H3T 1E2, Canada.; Orthopaedic Research Laboratory, Lady Davis Institute for Medical Research, McGill University, Montreal, QC H3T 1E2, Canada.

Subjects: Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/therapy ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/pathology

  • Source: Biomolecules [Biomolecules] 2025 Jun 16; Vol. 15 (6). Date of Electronic Publication: 2025 Jun 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease.

  • Authors : Lee KM; Faculty of Medicine Dentistry and Health Sciences, Department of Medicine, Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia.; Lupancu T

Subjects: Obesity*/Obesity*/Obesity*/complications ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/drug therapy ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/etiology

  • Source: PloS one [PLoS One] 2025 Jan 16; Vol. 20 (1), pp. e0317399. Date of Electronic Publication: 2025 Jan 16 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Interconnected Pathways: Exploring Inflammation, Pain, and Cognitive Decline in Osteoarthritis.

  • Authors : Tarasovs M; Department of Internal Diseases, Riga Stradins University, Hipokrata Str. 2, LV-1038 Riga, Latvia.; Autoimmunity Center, Riga East University Hospital, Clinic Gailezers, Hipokrata Str. 2, LV-1038 Riga, Latvia.

Subjects: Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/complications ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/urine ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 06; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Association between clinical and MRI-detected imaging findings for people with midfoot pain, a cross-sectional study.

  • Authors : Halstead J; Leeds Community Healthcare NHS Trust, Leeds, UK.; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Subjects: Magnetic Resonance Imaging*/Magnetic Resonance Imaging*/Magnetic Resonance Imaging*/methods ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/diagnostic imaging ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/complications

  • Source: Journal of foot and ankle research [J Foot Ankle Res] 2025 Mar; Vol. 18 (1), pp. e70019.Publisher: Wiley Country of Publication: United States NLM ID: 101471610 Publication Model: Print Cited Medium: Internet ISSN: 1757-1146

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Academic Journal

Barriers and facilitators to using a clinical decision support tool for the management of osteoarthritis pain in patients undergoing hemodialysis: a qualitative study.

  • Authors : Mohsen M; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.; Department of Nephrology, Toronto General Hospital - University Health Network, Toronto, ON, Canada.

Subjects: Renal Dialysis*/Renal Dialysis*/Renal Dialysis*/adverse effects ; Qualitative Research* ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/therapy

  • Source: BMC primary care [BMC Prim Care] 2024 Aug 19; Vol. 25 (1), pp. 308. Date of Electronic Publication: 2024 Aug 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9918300889006676 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibitory Effects of Reynoutria japonica Houtt. on Pain and Cartilage Breakdown in Osteoarthritis Based on Its Multifaceted Anti-Inflammatory Activity: An In Vivo and In Vitro Approach.

  • Authors : Jo HG; Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam-si 13120, Republic of Korea.; Naturalis Inc., 6 Daewangpangyo-ro, Bundang-gu, Seongnam-si 13549, Republic of Korea.

Subjects: Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/drug therapy ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/pathology ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 03; Vol. 25 (19). Date of Electronic Publication: 2024 Oct 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Time reduction with a mini power saw blade in first carpometacarpal Ensemble arthroplasty: a case report.

  • Authors : Garvey J; Advanced Hand and Plastic Surgery Center, 4710 N Habana Ave STE 100, Tampa, FL, 33614, USA. .; Lutz, FL, 33548, USA. .

Subjects: Carpometacarpal Joints*/Carpometacarpal Joints*/Carpometacarpal Joints*/surgery ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/surgery ; Arthroplasty*/Arthroplasty*/Arthroplasty*/methods

  • Source: Journal of medical case reports [J Med Case Rep] 2025 Jun 18; Vol. 19 (1), pp. 281. Date of Electronic Publication: 2025 Jun 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947

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