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  • 1-10 ل  1,323 نتائج ل ""Protein-tyrosine kinases""

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Subject : mutation
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Academic Journal

The Association Between Thromboembolic Events and ALK, ROS1, RET Rearrangements or EGFR Mutations in Patients With Advanced Lung Adenocarcinoma: A Retrospective Cohort Study.

  • Authors : Qian X; Department of Respiratory Disease, Thoracic Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Subjects: Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/genetics ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/genetics ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/pathology

  • Source: Thoracic cancer [Thorac Cancer] 2025 Aug; Vol. 16 (15), pp. e70141.Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Association between PD-L1 expression with EGFR , ALK , and ROS1 driver oncogene mutations in non-small cell lung cancer.

  • Authors : Onur D; Department of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.; Department of Pathology, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; B7-H1 Antigen*/B7-H1 Antigen*/B7-H1 Antigen*/genetics

  • Source: Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2025 Jan 01; Vol. 68 (1), pp. 36-41. Date of Electronic Publication: 2024 Jun 20.Publisher: Medknow Country of Publication: India NLM ID: 7605904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-5130

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Academic Journal

Exploring the mutational spectrum of key kinase genes PIK3CA, BRAF, EGFR, ALK and ROS1 in oral squamous cell carcinoma.

  • Authors : Nawab F; Institute of Basic Medical Sciences, Khyber Medical University, Phase V, Peshawar, 25000, Pakistan.; Naeem W

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/chemistry ; Mutation*

  • Source: BMC cancer [BMC Cancer] 2025 Aug 18; Vol. 25 (1), pp. 1333. Date of Electronic Publication: 2025 Aug 18.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis.

  • Authors : Yamaguchi T; Department of Thoracic Oncology, Aichi Cancer Center Hospital, 1-1, Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan. .; Shimizu J

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/mortality

  • Source: BMC cancer [BMC Cancer] 2024 Jul 15; Vol. 24 (1), pp. 842. Date of Electronic Publication: 2024 Jul 15.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Comparison of diagnostic performance between Oncomine Dx target test and AmoyDx panel for detecting actionable mutations in lung cancer.

  • Authors : Nagakubo Y; Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan.; Hirotsu Y

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/diagnosis ; Mutation*

  • Source: Scientific reports [Sci Rep] 2024 May 30; Vol. 14 (1), pp. 12480. Date of Electronic Publication: 2024 May 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Report

The association of ROS1 mutation with cancer immunity and its impact on the efficacy of pan-cancer immunotherapy.

  • Authors : Li Y; Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.; Second Affiliated Hospital, Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.

Subjects: Immunotherapy* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/immunology

  • Source: Journal of translational medicine [J Transl Med] 2024 Apr 30; Vol. 22 (1), pp. 403. Date of Electronic Publication: 2024 Apr 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay.

  • Authors : Lee KS; Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, 217 Gajeong-ro, Gajeong-dong, Yuseong-gu, Daejeon, 34113, Republic of Korea.

Subjects: Heterozygote* ; Mutation*; Developmental Disabilities/Developmental Disabilities/Developmental Disabilities/*enzymology

  • Source: Scientific reports [Sci Rep] 2020 Jun 17; Vol. 10 (1), pp. 9849. Date of Electronic Publication: 2020 Jun 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper.

  • Authors : Soverini S; Hematology/Oncology 'L. e A. Seràgnoli', Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, S. Orsola-Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy. .; Abruzzese E

Subjects: Mutation*; DNA Mutational Analysis/DNA Mutational Analysis/DNA Mutational Analysis/*methods ; Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/*genetics

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2019 Dec 05; Vol. 12 (1), pp. 131. Date of Electronic Publication: 2019 Dec 05.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

Axl is a novel target of celastrol that inhibits cell proliferation and migration, and increases the cytotoxicity of gefitinib in EGFR mutant non‑small cell lung cancer cells.

  • Authors : Lee YJ; Department of Pharmacology, College of Medicine, Catholic University of Daegu, Daegu 42472, Republic of Korea.; Kim SY

Subjects: Mutation*; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*genetics ; Gefitinib/Gefitinib/Gefitinib/*pharmacology

  • Source: Molecular medicine reports [Mol Med Rep] 2019 Apr; Vol. 19 (4), pp. 3230-3236. Date of Electronic Publication: 2019 Feb 14.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin.

  • Authors : Huang KY; Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei 11490, Taiwan.; Wang TH

Subjects: ErbB Receptors/ErbB Receptors/ErbB Receptors/*genetics ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*genetics ; Mutation/Mutation/Mutation/*genetics

  • Source: Biomolecules [Biomolecules] 2021 Aug 25; Vol. 11 (9). Date of Electronic Publication: 2021 Aug 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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  • 1-10 ل  1,323 نتائج ل ""Protein-tyrosine kinases""