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Academic Journal

[Lorlatinib primary hospital patient health management expert consensus (2025 edition)].

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy

  • Source: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2025 Jun 23; Vol. 47 (6), pp. 443-455.Publisher: Chinese Medical Association Country of Publication: China NLM ID: 7910681 Publication Model: Print Cited Medium: Print ISSN: 0253-3766

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Academic Journal

Efficacy and safety analysis of lorlatinib for ALK-positive advanced NSCLC: a multicentre real-world study in China.

  • Authors : Chen Z; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Army Medical University (Third Military Medical University), Chongqing, China.; Tang C

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics

  • Source: BMC cancer [BMC Cancer] 2025 Jul 25; Vol. 25 (1), pp. 1216. Date of Electronic Publication: 2025 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

A plug-and-play system for polycyclic tetramate macrolactam production and functionalization.

  • Authors : Glöckle A; Chair of Technical Biochemistry, Technische Universität Dresden, Bergstraße 66, 01069, Dresden, Germany.; Schuler S

Subjects: Streptomyces*/Streptomyces*/Streptomyces*/metabolism ; Streptomyces*/Streptomyces*/Streptomyces*/genetics ; Lactams, Macrocyclic*/Lactams, Macrocyclic*/Lactams, Macrocyclic*/metabolism

  • Source: Microbial cell factories [Microb Cell Fact] 2025 Jan 10; Vol. 24 (1), pp. 13. Date of Electronic Publication: 2025 Jan 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101139812 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2859

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Academic Journal

Successful intracranial response of lorlatinib after resistance with alectinib and brigatinib in patients with ALK-positive lung adenocarcinoma: Implications of CNS penetration rate of brigatinib.

  • Authors : Sato Y; Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.; Sato Y

Subjects: Organophosphorus Compounds*/Organophosphorus Compounds*/Organophosphorus Compounds*/therapeutic use ; Organophosphorus Compounds*/Organophosphorus Compounds*/Organophosphorus Compounds*/pharmacology ; Organophosphorus Compounds*/Organophosphorus Compounds*/Organophosphorus Compounds*/administration & dosage

  • Source: Thoracic cancer [Thorac Cancer] 2024 Aug; Vol. 15 (23), pp. 1772-1775. Date of Electronic Publication: 2024 Jun 24.Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Geldanamycins: Potent Hsp90 Inhibitors with Significant Potential in Cancer Therapy.

  • Authors : Abdullah O; College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.; Omran Z

Subjects: Benzoquinones*/Benzoquinones*/Benzoquinones*/chemistry ; Benzoquinones*/Benzoquinones*/Benzoquinones*/pharmacology ; Benzoquinones*/Benzoquinones*/Benzoquinones*/therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 20; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Enhanced Efficacy of Gastric Cancer Treatment through Targeted Exosome Delivery of 17-DMAG Anticancer Agent.

  • Authors : Park JH; Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.; Kim SJ

Subjects: Exosomes*/Exosomes*/Exosomes*/metabolism ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/drug therapy ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 12; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Structural Characterization of Heat Shock Protein 90β and Molecular Interactions with Geldanamycin and Ritonavir: A Computational Study.

  • Authors : Lima CR; Laboratory of Biological System Modeling, Centro de Desenvolvimento Tecnológico em Saúde (CDTS), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, Brazil.; Antunes D

Subjects: Lactams, Macrocyclic*/Lactams, Macrocyclic*/Lactams, Macrocyclic*/pharmacology ; Lactams, Macrocyclic*/Lactams, Macrocyclic*/Lactams, Macrocyclic*/chemistry ; Ritonavir*/Ritonavir*/Ritonavir*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 12; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Comparative efficacy and safety of Sofosbuvir/Velpatasvir and Danoprevir for the treatment of chronic hepatitis C: the real-world data in China.

  • Authors : Zhou Y; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.; Liang M

Subjects: Benzimidazoles* ; Benzopyrans* ; Carbamates*

  • Source: BMC gastroenterology [BMC Gastroenterol] 2024 Feb 14; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2024 Feb 14.Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X

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Academic Journal

Efficacy and safety of glecaprevir and pibrentasvir in Saudi patients with chronic hepatitis C virus infection at a major tertiary hospital.

  • Authors : Ruwayni AA; From the Department of Pharmaceutical Care (Ruwayni), Armed Forces Hospital, Jazan, and from the Department of Pharmaceutical Care (Ruwayni, AlObary, Alyahya), Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia.; AlObary EE

Subjects: Hepatitis C, Chronic*/Hepatitis C, Chronic*/Hepatitis C, Chronic*/drug therapy ; Sulfonamides* ; Aminoisobutyric Acids*

  • Source: Saudi medical journal [Saudi Med J] 2024 Jan; Vol. 45 (1), pp. 34-39.Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441

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Academic Journal

The Odd Couple(s): An Overview of Beta-Lactam Antibiotics Bearing More Than One Pharmacophoric Group.

  • Authors : De Rosa M; Department of Chemistry and Biology 'A. Zambelli', University of Salerno, 84084 Fisciano (SA), Italy.; Verdino A

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*chemistry ; Azetidines/Azetidines/Azetidines/*chemistry ; Lactams, Macrocyclic/Lactams, Macrocyclic/Lactams, Macrocyclic/*chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 09; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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