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Academic Journal

Pro-Inflammatory Activation Promotes Atherogenic Endothelial Phenotype in Male and Female Human Umbilical Endothelial Vein Cells (HUVECs).

Authors : Lorenz M; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany.; Deutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin, CCM, Charitéplatz 1, 10117 Berlin, Germany.

Subjects: Human Umbilical Vein Endothelial Cells*/Human Umbilical Vein Endothelial Cells*/Human Umbilical Vein Endothelial Cells*/metabolism ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2026 Mar 27; Vol. 27 (7). Date of Electronic Publication: 2026 Mar 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro-Inflammatory Phenotype of Senescent Cells.

Authors : Jiang B; School of Pharmacy, Institute of Aging Medicine, Binzhou Medical University, Yantai, Shandong, China.; Zhang H

Subjects: PQQ Cofactor*/PQQ Cofactor*/PQQ Cofactor*/pharmacology ; Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; Senescence-Associated Secretory Phenotype*/Senescence-Associated Secretory Phenotype*/Senescence-Associated Secretory Phenotype*/drug effects

Source: Aging cell [Aging Cell] 2025 Sep; Vol. 24 (9), pp. e70138. Date of Electronic Publication: 2025 Jun 19.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Monocyte clusters suggestive of a chronic inflammatory phenotype are associated with reduced endothelial function in Veterans with respiratory symptoms.

Authors : Pappas G; Airborne Hazards and Burn Pits Center of Excellence, Veterans Affairs New Jersey Health Care System, East Orange, New Jersey, United States of America.; Gardner C

Subjects: Monocytes*/Monocytes*/Monocytes*/immunology ; Monocytes*/Monocytes*/Monocytes*/metabolism ; Monocytes*/Monocytes*/Monocytes*/pathology

Source: PloS one [PLoS One] 2026 Feb 10; Vol. 21 (2), pp. e0338883. Date of Electronic Publication: 2026 Feb 10 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Role of Protein Kinases in the Suppressive Phenotype of Myeloid-Derived Suppressor Cells.

Authors : Kali A; Laboratory of Molecular Immunology and Immunobiotechnology, M.A. Aitkhozhin Institute of Molecular Biology and Biochemistry, Almaty 050012, Kazakhstan.; Abdolla N

Subjects: Protein Kinases*/Protein Kinases*/Protein Kinases*/metabolism ; Myeloid-Derived Suppressor Cells*/Myeloid-Derived Suppressor Cells*/Myeloid-Derived Suppressor Cells*/cytology ; Inflammation*/Inflammation*/Inflammation*/immunology

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 19; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Prominent Pro-Inflammatory Phenotype Is Observed in Replication and Stress-Induced Senescent Mast Cells.

Authors : Ibarra-Sánchez A; Pharmacobiology Department, Center for Research and Advanced Studies (Cinvestav) of the National Polytechnic Institute (IPN), Mexico City, Mexico.; Center for Research in Aging, Cinvestav, Mexico City, Mexico.

Subjects: Mast Cells*/Mast Cells*/Mast Cells*/metabolism ; Mast Cells*/Mast Cells*/Mast Cells*/drug effects ; Mast Cells*/Mast Cells*/Mast Cells*/pathology

Source: Aging cell [Aging Cell] 2025 Oct; Vol. 24 (10), pp. e70186. Date of Electronic Publication: 2025 Aug 28.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pluripotent Cells Expressing APOE4 Exhibit a Pronounced Pro-Apoptotic Phenotype Accompanied by Markers of Hyperinflammation and a Blunted NF-κB Response.

Authors : Schulten W; Department of Cell Biology, University of Bielefeld, 33615 Bielefeld, Germany.; Czaniera NJ

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Apolipoprotein E4*/Apolipoprotein E4*/Apolipoprotein E4*/metabolism ; Apolipoprotein E4*/Apolipoprotein E4*/Apolipoprotein E4*/genetics

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 23; Vol. 26 (19). Date of Electronic Publication: 2025 Sep 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Proteomic Analysis Uncovers Enhanced Inflammatory Phenotype and Distinct Metabolic Changes in IDH1 Mutant Glioma Cells.

Authors : Ravn Berg S; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, 7491 Trondheim, Norway.

Subjects: Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/genetics ; Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/Isocitrate Dehydrogenase*/metabolism ; Glioma*/Glioma*/Glioma*/genetics

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 18; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Methamphetamine Induces Metallothionein 1 Expression and an Inflammatory Phenotype in Primary Human HIV-Infected Macrophages.

Authors : Weiselberg J; Department of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA.; Niu M

Subjects: Metallothionein*/Metallothionein*/Metallothionein*/genetics ; Metallothionein*/Metallothionein*/Metallothionein*/metabolism ; Methamphetamine*/Methamphetamine*/Methamphetamine*/pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 12; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Substrate stiffness and shear stress collectively regulate the inflammatory phenotype in cultured human brain microvascular endothelial cells.

Authors : Yates AK; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/physiology ; Brain*/Brain*/Brain*/blood supply

Source: Fluids and barriers of the CNS [Fluids Barriers CNS] 2025 Jul 15; Vol. 22 (1), pp. 73. Date of Electronic Publication: 2025 Jul 15.Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118

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Academic Journal

Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling.

Authors : Santos L; Laboratory of Metabolic Diseases and Aging, Institut Pasteur de Montevideo, Montevideo, Uruguay.; Fort RS

Subjects: Obesity*/Obesity*/Obesity*/metabolism ; Obesity*/Obesity*/Obesity*/genetics ; Obesity*/Obesity*/Obesity*/pathology

Source: PloS one [PLoS One] 2025 May 02; Vol. 20 (5), pp. e0322732. Date of Electronic Publication: 2025 May 02 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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نتائج البحث

فلترة النتائج

Pro-Inflammatory Activation Promotes Atherogenic Endothelial Phenotype in Male and Female Human Umbilical Endothelial Vein Cells (HUVECs).

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro-Inflammatory Phenotype of Senescent Cells.

Monocyte clusters suggestive of a chronic inflammatory phenotype are associated with reduced endothelial function in Veterans with respiratory symptoms.

The Role of Protein Kinases in the Suppressive Phenotype of Myeloid-Derived Suppressor Cells.

A Prominent Pro-Inflammatory Phenotype Is Observed in Replication and Stress-Induced Senescent Mast Cells.

Pluripotent Cells Expressing APOE4 Exhibit a Pronounced Pro-Apoptotic Phenotype Accompanied by Markers of Hyperinflammation and a Blunted NF-κB Response.

Proteomic Analysis Uncovers Enhanced Inflammatory Phenotype and Distinct Metabolic Changes in IDH1 Mutant Glioma Cells.

Methamphetamine Induces Metallothionein 1 Expression and an Inflammatory Phenotype in Primary Human HIV-Infected Macrophages.

Substrate stiffness and shear stress collectively regulate the inflammatory phenotype in cultured human brain microvascular endothelial cells.

Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling.

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