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Development of novel lysosome-related signatures and their potential target drugs based on bulk RNA-seq and scRNA-seq for diabetic foot ulcers

• Authors : Longhai Tan; Junjun Qu; Junxia Wang

Subjects: Diabetic foot ulcer; Lysosome-related genes; Artificial neural network

• Source: Human Genomics, Vol 18, Iss 1, Pp 1-16 (2024)

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Lipids, lipid-lowering drugs and lateral epicondylitis of the humerus: a drug-targeted Mendelian randomization study

• Authors : Meng-Meng Liu; Xiang Chen; Xiao-Hang Bao

Subjects: lipids; lipid-lowering drugs; lateral epicondylitis

• Source: Frontiers in Genetics, Vol 15 (2024)

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Daily habits, diseases, drugs and knee osteoarthritis: a two-sample Mendelian randomization analysis

• Authors : Yaqiong Zhou; Qi Wang; Liping Chen

Subjects: Mendelian randomization; daily habits; diseases

• Source: Frontiers in Genetics, Vol 15 (2024)

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Lipid-lowering drugs and risk of rapid renal function decline: a mendelian randomization study

• Authors : Zhicheng Zhao; Yu Wan; Han Fu

Subjects: Chronic kidney disease; Mendelian randomization; Drug target

• Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-9 (2024)

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Considerations for the genotoxicity assessment of middle size peptide drugs containing non-canonical amino acid residues

• Authors : Masayuki Mishima; Kei-ichi Sugiyama

Subjects: Peptide drugs; Cyclic peptides; Genotoxicity

• Source: Genes and Environment, Vol 45, Iss 1, Pp 1-6 (2023)

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Identification of key immune-related genes and potential therapeutic drugs in diabetic nephropathy based on machine learning algorithms

• Authors : Chang Guo; Wei Wang; Ying Dong

Subjects: Diabetic nephropathy; Immune-related genes; Machine learning

• Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-16 (2024)

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Association of lipid-lowering drugs with risk of sarcopenia: a drug target mendelian randomization study and meta-analysis

• Authors : Jiaxin Li; Chenyang Zang; Hui Lv

Subjects: HMGCR; PCSK9; NPC1L1

• Source: Human Genomics, Vol 18, Iss 1, Pp 1-12 (2024)

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Drug repurposing based on the DTD-GNN graph neural network: revealing the relationships among drugs, targets and diseases

• Authors : Wenjun Li; Wanjun Ma; Mengyun Yang

Subjects: Drug repurposing; Drug-Target-Disease ternary relationship; DTD-GNN model

• Source: BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)

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Overall survival for oncology drugs approved for genomic indications.

• Authors : Haslam, Alyson; Kim, Myung Sun; Prasad, Vinay

Subjects: Humans; Neoplasms; Antineoplastic Agents

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Using Human 'Personalized' Cybrids to Identify Drugs/Agents That Can Regulate Chronic Lymphoblastic Leukemia Mitochondrial Dysfunction.

• Authors : Singh, Lata; Atilano, Shari; Chwa, Marilyn

Subjects: Mitochondria; Humans; Reactive Oxygen Species

• Source: International journal of molecular sciences. 24(13)

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