نتائج البحث

Crosstalk between the DNA damage response and cellular senescence drives aging and age-related diseases.

• Authors : Ahmad A; Department of Ophthalmology, College of Medicine, King Saud University Riyadh, Riyadh, Saudi Arabia.; Braden A

Subjects: Cellular Senescence* ; DNA Damage* ; Aging*/Aging*/Aging*/metabolism

• Source: Seminars in immunopathology [Semin Immunopathol] 2024 Aug 02; Vol. 46 (3-4), pp. 10. Date of Electronic Publication: 2024 Aug 02.Publisher: Springer Country of Publication: Germany NLM ID: 101308769 Publication Model: Electronic Cited Medium: Internet ISSN: 1863-2300

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Replication stress as a driver of cellular senescence and aging.

• Authors : Herr LM; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.; Schaffer ED

Subjects: Cellular Senescence* ; DNA Replication* ; Aging*

• Source: Communications biology [Commun Biol] 2024 May 22; Vol. 7 (1), pp. 616. Date of Electronic Publication: 2024 May 22.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells.

• Authors : Qin L; NHC Key Laboratory of Radiobiology (Jilin University), School of Public Health, Jilin University, Changchun, 130021, Jilin, People's Republic of China.; Tang G

Subjects: X-linked Nuclear Protein*/X-linked Nuclear Protein*/X-linked Nuclear Protein*/genetics ; X-linked Nuclear Protein*/X-linked Nuclear Protein*/X-linked Nuclear Protein*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Jan 04; Vol. 15 (1), pp. 793. Date of Electronic Publication: 2025 Jan 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence.

• Authors : Kang T; Buck Institute for Research on Aging, Novato, CA 94945, USA.; Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/genetics ; DNA Damage*; Animals

• Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 Jul 05; Vol. 13 (7).Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN:

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USP14 inhibition promotes DNA damage repair and represses ovarian granulosa cell senescence in premature ovarian insufficiency.

• Authors : Ma LZ; Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Northern Road, Guangzhou, Guangdong, 510515, China.; Wang A

Subjects: Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/pathology ; Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/metabolism ; Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/Primary Ovarian Insufficiency*/genetics

• Source: Journal of translational medicine [J Transl Med] 2024 Sep 11; Vol. 22 (1), pp. 834. Date of Electronic Publication: 2024 Sep 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Residual Foci of DNA Damage Response Proteins in Relation to Cellular Senescence and Autophagy in X-Ray Irradiated Fibroblasts.

• Authors : Osipov A; N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russia.; Chigasova A

Subjects: Histones*/Histones*/Histones*/metabolism ; DNA Damage*; X-Rays

• Source: Cells [Cells] 2023 Apr 21; Vol. 12 (8). Date of Electronic Publication: 2023 Apr 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Studies on the role of moderate doses of ionizing radiation-induced cellular senescence in mouse lung tissue

• Authors : Lingyu Zhang; Lina Cai; Yashi Cai

Subjects: Mice, Inbred C57BL; Male; Mice

• Source: International Journal of Radiation Biology. 100:1650-1664

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Mechanisms and Regulation of Cellular Senescence.

• Authors : Roger L; Structure and Instability of Genomes Laboratory, Muséum National d'Histoire Naturelle (MNHN), CNRS-UMR 7196/INSERM U1154, 43 Rue Cuvier, 75005 Paris, France.; Tomas F

Subjects: Aging* ; Cellular Senescence* ; DNA Damage*

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 06; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Role of C-Terminal Phosphorylation of Lamin A in DNA Damage and Cellular Senescence.

• Authors : Ao Y; Guangdong Key Laboratory for Genome Stability & Human Disease Prevention, Carson International Cancer Center, Department of Biochemistry & Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518055, China.; Shenzhen Key Laboratory for Systemic Aging and Intervention, National Engineering Research Center for Biotechnology (Shenzhen), Shenzhen University, Shenzhen 518055, China.

Subjects: DNA Damage* ; Lamin Type A*/Lamin Type A*/Lamin Type A*/metabolism; Cellular Senescence/Cellular Senescence/Cellular Senescence/genetics

• Source: Cells [Cells] 2023 Feb 16; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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PRDM16 Reduces Cellular Senescence by Upregulating GSTM1.

• Authors : Yuan, Qian¹ (AUTHOR); Zhu, Yuting¹ (AUTHOR); Tang, Ben¹ (AUTHOR)

• Source: Advanced Science. Sep2025, p1. 19p. 9 Illustrations.

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