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Academic Journal

Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management.

  • Authors : Chehadi AC; Department of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, Brazil.; Pereira de Lima E

Subjects: Tryptophan*/Tryptophan*/Tryptophan*/metabolism ; Tryptophan*/Tryptophan*/Tryptophan*/therapeutic use ; Major Depressive Disorder*/Major Depressive Disorder*/Major Depressive Disorder*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jan 01; Vol. 27 (1). Date of Electronic Publication: 2026 Jan 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Melatonin Ameliorates Depressive-Like Behaviors in Ovariectomized Mice by Improving Tryptophan Metabolism via Inhibition of Gut Microbe Alistipes Inops.

  • Authors : Zheng KY; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Gao B

Subjects: Melatonin*/Melatonin*/Melatonin*/pharmacology ; Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/drug effects ; Tryptophan*/Tryptophan*/Tryptophan*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (34), pp. e2309473. Date of Electronic Publication: 2024 Jul 08.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Effects of phototherapy on biopterin, neopterin, tryptophan, and behavioral neuroinflammatory reaction in patients with post-stroke depression.

  • Authors : Liu L; Department of Mental Health, The First Hospital of Hebei Medical University, No.89 Donggang Road, Shijiazhuang, 050031, Hebei, China.; Hebei Institute of Mental Health, Shijiazhuang, Hebei, China.

Subjects: Neopterin*/Neopterin*/Neopterin*/blood ; Tryptophan*/Tryptophan*/Tryptophan*/blood ; Tryptophan*/Tryptophan*/Tryptophan*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 07; Vol. 14 (1), pp. 18368. Date of Electronic Publication: 2024 Aug 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

HTR1A, TPH2, and 5-HTTLPR Polymorphisms and Their Impact on the Severity of Depressive Symptoms and on the Concentration of Tryptophan Catabolites during Hepatitis C Treatment with Pegylated Interferon-α2a and Oral Ribavirin (PEG-IFN-α2a/RBV).

  • Authors : Pawlowski T; Department of Psychiatry, Wrocław Medical University, 50-367 Wrocław, Poland.; Malyszczak K

Subjects: Depression*/Depression*/Depression*/genetics ; Depression*/Depression*/Depression*/metabolism ; Hepatitis C, Chronic*/Hepatitis C, Chronic*/Hepatitis C, Chronic*/complications

  • Source: Cells [Cells] 2023 Mar 22; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

A Peripheral Mechanism of Depression: Disturbed Intestinal Epithelial Per2 Gene Expression Causes Depressive Behaviors in Mice with Circadian Rhythm Disruption via Gut Barrier Damage and Microbiota Dysbiosis.

  • Authors : Zhang H; Department of Pathophysiology, Key Laboratory of Ministry of Education/Hubei province for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.; Qin X

Subjects: Period Circadian Proteins*/Period Circadian Proteins*/Period Circadian Proteins*/genetics ; Period Circadian Proteins*/Period Circadian Proteins*/Period Circadian Proteins*/metabolism ; Depression*/Depression*/Depression*/genetics

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (43), pp. e01818. Date of Electronic Publication: 2025 Aug 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Inhibition of Indoleamine 2,3-Dioxygenase Exerts Antidepressant-like Effects through Distinct Pathways in Prelimbic and Infralimbic Cortices in Rats under Intracerebroventricular Injection with Streptozotocin.

  • Authors : Qin Y; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.; Hu X

Subjects: Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism ; Streptozocin*/Streptozocin*/Streptozocin*/toxicity ; Kynurenine*/Kynurenine*/Kynurenine*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 08; Vol. 25 (13). Date of Electronic Publication: 2024 Jul 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state.

  • Authors : Bruzzone SEP; Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Subjects: DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/Serotonin Plasma Membrane Transport Proteins*/genetics ; Tryptophan Hydroxylase*/Tryptophan Hydroxylase*/Tryptophan Hydroxylase*/genetics

  • Source: Clinical epigenetics [Clin Epigenetics] 2024 May 27; Vol. 16 (1), pp. 71. Date of Electronic Publication: 2024 May 27.Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083

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Academic Journal

Investigation of the Effect of Tai Chi Training on Depressive Symptoms in Perimenopausal Women on the Basis of Serum Kynurenine Metabolites.

  • Authors : Liu J; Department of Physical Education, Lyuliang University, Lv Liang, Shan, China.; Si J

Subjects: Kynurenine*/Kynurenine*/Kynurenine*/blood ; Perimenopause*/Perimenopause*/Perimenopause*/psychology ; Perimenopause*/Perimenopause*/Perimenopause*/blood

  • Source: Experimental aging research [Exp Aging Res] 2025 May-Jun; Vol. 51 (3), pp. 331-349. Date of Electronic Publication: 2024 Jul 18.Publisher: Routledge Country of Publication: United States NLM ID: 7603335 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease.

  • Authors : Chen LM; Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No.110 Ganhe Road, Shanghai, 200437, China.; Key Laboratory of Acupuncture and Immunological Effects, Shanghai University of Traditional Chinese Medicine, No. 650 South Wanping Road, Shanghai, 200030, China.

Subjects: Brain-Gut Axis*/Brain-Gut Axis*/Brain-Gut Axis*/physiology; Depression/Depression/Depression/*complications ; Depression/Depression/Depression/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jun 14; Vol. 18 (1), pp. 135. Date of Electronic Publication: 2021 Jun 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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