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Academic Journal

Redefining the Phenotype of Heat Shock Protein 90 (Hsp90) Inhibitors.

Authors : Wang Y; Department of Medicine, University of New South Wales, Australia.; Koay YC

Subjects: Benzoquinones/Benzoquinones/Benzoquinones/*chemistry ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors ; Isoxazoles/Isoxazoles/Isoxazoles/*chemistry

Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2017 Feb 10; Vol. 23 (9), pp. 2010-2013. Date of Electronic Publication: 2017 Jan 20.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765

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Academic Journal

Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.

Authors : Huyan T; a Key Laboratory for Space Bioscience and Space Biotechnology, School of Life Sciences, Northwestern Polytechnical University , Xi'an, Shaanxi , People's Republic of China.; Li Q

Subjects: Adenine/Adenine/Adenine/*analogs & derivatives ; Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors

Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2016; Vol. 38 (2), pp. 77-86. Date of Electronic Publication: 2015 Dec 08.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional characterization of heat-shock protein 90 from Oryza sativa and crystal structure of its N-terminal domain.

Authors : Raman S; Molecular Biophysics Unit, Indian institute of Science, Bangalore, India 560 012, India.; Suguna K

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*analogs & derivatives ; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*chemistry ; Benzoquinones/Benzoquinones/Benzoquinones/*chemistry

Source: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2015 Jun; Vol. 71 (Pt 6), pp. 688-96. Date of Electronic Publication: Publisher: John Wiley & Sons Inc Country of Publication: United States NLM ID: 101620319 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses.

Authors : Tukaj S; Department of Dermatology, University of Lübeck, Lübeck, Germany.; Tiburzy B

Subjects: B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*drug effects ; Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors

Source: Experimental dermatology [Exp Dermatol] 2014 Aug; Vol. 23 (8), pp. 585-90.Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9301549 Publication Model: Print Cited Medium: Internet ISSN: 1600-0625

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Academic Journal

Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB.

Authors : Trojandt S; Reske-Kunz AB; Bros M

Subjects: Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; Dendritic Cells/Dendritic Cells/Dendritic Cells/*drug effects ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors

Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2014 Feb 13; Vol. 33, pp. 16. Date of Electronic Publication: 2014 Feb 13.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

Heat shock protein 90: role in enterovirus 71 entry and assembly and potential target for therapy.

Authors : Tsou YL; Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli, County, Taiwan ; Graduate Program of Biotechnology in Medicine, Institute of Molecular and Cellular Biology, National Tsing Hua University, Hsinchu, Taiwan.

Subjects: Molecular Targeted Therapy*; Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; Enterovirus A, Human/Enterovirus A, Human/Enterovirus A, Human/*drug effects

Source: PloS one [PLoS One] 2013 Oct 02; Vol. 8 (10), pp. e77133. Date of Electronic Publication: 2013 Oct 02 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma.

Authors : Murata T; Division of Virology, Aichi Cancer Center Research Institute, Nagoya, Aichi, Japan.; Iwata S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; Epstein-Barr Virus Infections/Epstein-Barr Virus Infections/Epstein-Barr Virus Infections/*drug therapy

Source: PloS one [PLoS One] 2013 May 03; Vol. 8 (5), pp. e63566. Date of Electronic Publication: 2013 May 03 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet

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Academic Journal

Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.

Authors : Giubellino A; Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, Maryland, United States of America. ; Sourbier C

Subjects: Molecular Targeted Therapy*; Adrenal Gland Neoplasms/Adrenal Gland Neoplasms/Adrenal Gland Neoplasms/*drug therapy ; Benzoquinones/Benzoquinones/Benzoquinones/*therapeutic use

Source: PloS one [PLoS One] 2013; Vol. 8 (2), pp. e56083. Date of Electronic Publication: 2013 Feb 14.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.

Authors : Hackl C; Department of Surgery, University of Regensburg Medical Center, Franz-Josef Strauß Allee 11, 93042 Regensburg, Germany.; Lang SA

Subjects: Activating Transcription Factor 3/Activating Transcription Factor 3/Activating Transcription Factor 3/*metabolism ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology

Source: BMC cancer [BMC Cancer] 2010 Dec 03; Vol. 10, pp. 668. Date of Electronic Publication: 2010 Dec 03.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia.

Authors : Lancet JE; H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. ; Gojo I

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Benzoquinones/Benzoquinones/Benzoquinones/*administration & dosage ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors

Source: Leukemia [Leukemia] 2010 Apr; Vol. 24 (4), pp. 699-705. Date of Electronic Publication: 2010 Jan 28.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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فلترة النتائج

Redefining the Phenotype of Heat Shock Protein 90 (Hsp90) Inhibitors.

Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.

Functional characterization of heat-shock protein 90 from Oryza sativa and crystal structure of its N-terminal domain.

Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses.

Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB.

Heat shock protein 90: role in enterovirus 71 entry and assembly and potential target for therapy.

Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma.

Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.

Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia.

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