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  • 1-10 ل  15,344 نتائج ل ""Nucleus""

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Subject : apoptosis
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Academic Journal

Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells.

  • Authors : Zhang H; Spinal Surgery Department 2, Hebei Medical University Third Hospital, Shijiazhuang, Hebei 050011, P.R. China.; Zhang D

Subjects: Exosomes*/Exosomes*/Exosomes*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/cytology

  • Source: Molecular medicine reports [Mol Med Rep] 2025 May; Vol. 31 (5). Date of Electronic Publication: 2025 Mar 07.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.

  • Authors : Jia Y; Department of Minimally Invasive Spine Surgery, Tianjin Hospital, Tianjin, China.; Graduate School, Tianjin Medical University, Tianjin, China.

Subjects: Omeprazole*/Omeprazole*/Omeprazole*/adverse effects ; Omeprazole*/Omeprazole*/Omeprazole*/toxicity ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 May 03; Vol. 20 (1), pp. 443. Date of Electronic Publication: 2025 May 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

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Academic Journal

MANF overexpression ameliorates oxidative stress-induced apoptosis of human nucleus pulposus cells by facilitating mitophagy through promoting MFN2 expression.

  • Authors : Ma L; Department of Spine Surgery, The First Affiliated Hospital of Xinjiang Medical University, No.137, Liyu Mountain South Road, Urumqi City, 830054, Xinjiang Province, China.; Department of Minimally Invasive Spine Surgery, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Province, China.

Subjects: Mitophagy*/Mitophagy*/Mitophagy*/genetics ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/metabolism ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/pathology

  • Source: Scientific reports [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 476. Date of Electronic Publication: 2025 Jan 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

FSTL1 accelerates nucleus pulposus-derived mesenchymal stem cell apoptosis in intervertebral disc degeneration by activating TGF-β-mediated Smad2/3 phosphorylation.

  • Authors : Yan X; Department of Orthopedics and Spine Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, China.; Laboratory of Spinal and Spinal Cord Injury Regeneration and Repair, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, China.

Subjects: Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/pathology ; Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/metabolism ; Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/genetics

  • Source: Journal of translational medicine [J Transl Med] 2025 Feb 26; Vol. 23 (1), pp. 232. Date of Electronic Publication: 2025 Feb 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

Quercetin Alleviates Hyperglycemic-Generated Endoplasmic Reticulum Stress-Contacted Apoptosis of Rat Nucleus Pulposus Cells.

  • Authors : Yu Z; Department of Articular Orthopaedics, The Third Affiliated Hospital of Soochow University, Changzhou, China.; Wang X

Subjects: Quercetin*/Quercetin*/Quercetin*/pharmacology ; Quercetin*/Quercetin*/Quercetin*/therapeutic use ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Balkan medical journal [Balkan Med J] 2025 Jan 02; Vol. 42 (1), pp. 27-36.Publisher: Galenos Publishing House Country of Publication: Turkey NLM ID: 101571817 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The Role of the Bone Morphogenetic Protein Antagonist Noggin in Nucleus Pulposus Intervertebral Disc Cells.

  • Authors : Chen S; Tissue Engineering for Orthopedics & Mechanobiology (TOM), Bone & Joint Program, Department for BioMedical Research (DBMR), Faculty of Medicine, University of Bern, CH-3008 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, CH-3012 Bern, Switzerland.

Subjects: Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/metabolism ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/pathology ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/cytology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 02; Vol. 25 (21). Date of Electronic Publication: 2024 Nov 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

HDAC/H3K27ac-mediated transcription of NDUFA3 exerts protective effects on high glucose-treated human nucleus pulposus cells through improving mitochondrial function.

  • Authors : Zheng C; Department of Spinal and Spinal Surgery, Henan Key Laboratory for Intelligent Precision Orthopedic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, No.7, Wei Wu Road, Jinshui District, Zhengzhou, 450003, China.; Xinxiang Medical University, 601 Jinsui Avenue, Hongqi District, Xinxiang City, Henan Province, Xinxiang, 453003, China.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Electron Transport Complex I*/Electron Transport Complex I*/Electron Transport Complex I*/metabolism ; Electron Transport Complex I*/Electron Transport Complex I*/Electron Transport Complex I*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Sep 10; Vol. 14 (1), pp. 21165. Date of Electronic Publication: 2024 Sep 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Single-cell RNA-seq analysis reveals the Wnt/Ca 2+ signaling pathway with inflammation, apoptosis in nucleus pulposus degeneration.

  • Authors : Wang P; Guangzhou Red Cross Hospital, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, Guangdong Province, 510220, China.; Guizhou Medical University, Guizhou Medical University, Guiyang, Guizhou Province, 550025, China.

Subjects: Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/metabolism ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/pathology ; Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/metabolism

  • Source: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Apr 23; Vol. 25 (1), pp. 321. Date of Electronic Publication: 2024 Apr 23.Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474

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Academic Journal

The Role of Hydrogen Sulfide in the Localization and Structural-Functional Organization of p53 Following Traumatic Brain Injury: Development of a YOLO Model for Detection and Quantification of Apoptotic Nuclei.

  • Authors : Kirichenko E; Research Laboratory 'Medical Digital Images Based on the Basic Model', Department of Bioengineering, Faculty of Bioengineering and Veterinary Medicine, Don State Technical University, 344000 Rostov-on-Don, Russia.; Bachurin S

Subjects: Hydrogen Sulfide*/Hydrogen Sulfide*/Hydrogen Sulfide*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 24; Vol. 26 (11). Date of Electronic Publication: 2025 May 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Baicalin suppresses interleukin-1β-induced apoptosis, inflammatory response, oxidative stress, and extracellular matrix degradation in human nucleus pulposus cells.

  • Authors : Bai X; The Fifth Department of Orthopedics, Baoding No.1 Central Hospital, Baoding, China.; Yao M

Subjects: Apoptosis* ; Flavonoids*/Flavonoids*/Flavonoids*/pharmacology ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/metabolism

  • Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2023 Dec; Vol. 45 (4), pp. 433-442. Date of Electronic Publication: 2023 Jan 19.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  15,344 نتائج ل ""Nucleus""