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Academic Journal

Resistance mechanisms and approach to chronic lymphocytic leukemia after BTK inhibitor therapy.

  • Authors : Gruessner C; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Wiestner A

Subjects: Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors ; Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/genetics ; Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/metabolism

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2025 Jul; Vol. 66 (7), pp. 1176-1188. Date of Electronic Publication: 2025 Feb 19.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pro-Apoptotic Activity of 1-(4,5,6,7-Tetrabromo-1 H -benzimidazol-1-yl)propan-2-one, an Intracellular Inhibitor of PIM-1 Kinase in Acute Lymphoblastic Leukemia and Breast Cancer Cells.

  • Authors : Wińska P; Faculty of Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664 Warsaw, Poland.; Wielechowska M

Subjects: Proto-Oncogene Proteins c-pim-1*/Proto-Oncogene Proteins c-pim-1*/Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors ; Proto-Oncogene Proteins c-pim-1*/Proto-Oncogene Proteins c-pim-1*/Proto-Oncogene Proteins c-pim-1*/metabolism ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 19; Vol. 26 (12). Date of Electronic Publication: 2025 Jun 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cytotoxic activity of Ganoderma weberianum-sichuanese isolated from the Lower Volta River Basin of Ghana against human prostate carcinoma (PC-3), leukemic T cell (Jurkat), and plasmacytoid dendritic cell (pDC)-derived acute leukemia (PMDC05) cell lines.

  • Authors : Adotey G; Science Laboratory Department, Accra Technical University, Accra, Ghana.; Alolga RN

Subjects: Ganoderma*/Ganoderma*/Ganoderma*/chemistry ; Ganoderma*/Ganoderma*/Ganoderma*/isolation & purification ; Ganoderma*/Ganoderma*/Ganoderma*/genetics

  • Source: PloS one [PLoS One] 2025 Jul 11; Vol. 20 (7), pp. e0327087. Date of Electronic Publication: 2025 Jul 11 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Feeder Cell Detachment in Drug Response Profiling of Leukemia Cell Coculture Can Be Prevented by Conditioned Medium.

  • Authors : Vonkova I; CZ-OPENSCREEN, National Infrastructure for Chemical Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Martinkova O

Subjects: Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/cytology ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/drug effects

  • Source: Cancer medicine [Cancer Med] 2025 Jul; Vol. 14 (14), pp. e71070.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines.

  • Authors : Kalkan FN; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Yildiz MS

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Scientific reports [Sci Rep] 2025 Jun 03; Vol. 15 (1), pp. 19431. Date of Electronic Publication: 2025 Jun 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Comparative Analysis of Cardiovascular Events Associated With Acalabrutinib Versus Ibrutinib in Chronic Lymphocytic Leukemia: Insights From a Global Federated Network.

  • Authors : Majrashi A; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, UK.; Department of Emergency Medical Services, College of Nursing & Health Sciences, Jazan University, Jazan, Saudi Arabia.

Subjects: Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy ; Benzamides*/Benzamides*/Benzamides*/adverse effects ; Benzamides*/Benzamides*/Benzamides*/administration & dosage

  • Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2025 Jun; Vol. 13 (3), pp. e70113.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Academic Journal

ML385, a selective inhibitor of Nrf2, demonstrates efficacy in the treatment of adult T-cell leukemia.

  • Authors : Ishikawa C; Department of Microbiology and Oncology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan.; Division of Health Sciences, Transdisciplinary Research Organization for Subtropics and Island Studies, University of the Ryukyus, Nishihara, Okinawa, Japan.

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/antagonists & inhibitors ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/genetics

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2025 Apr; Vol. 66 (4), pp. 721-732. Date of Electronic Publication: 2024 Dec 17.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and Biological Evaluation of Quercetagetin Derivatives as the Inhibitors of Mcl-1 and Bcl-2 Against Leukemia.

  • Authors : Li K; Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.; Chinese Medicinal Materials Breeding Innovation Center of Yuelushan Laboratory, Changsha 410128, China.

Subjects: Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/antagonists & inhibitors ; Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/metabolism ; Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/Myeloid Cell Leukemia Sequence 1 Protein*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Mar 18; Vol. 26 (6). Date of Electronic Publication: 2025 Mar 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells.

  • Authors : Wu T; Department of Chemistry, Fudan University, Shanghai 200433, China.; Chen Y

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2025 May 27; Vol. 30 (11). Date of Electronic Publication: 2025 May 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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