نتائج البحث

E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models.

• Authors : Garcia-Rodríguez L; Programa Gens i Malaltia, Centre de Regulació Genòmica, Parc de Recerca Biomèdica de Barcelona, UPF, Barcelona, Spain.; Abate-Daga D

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Cadherins/Cadherins/Cadherins/*genetics ; Ganciclovir/Ganciclovir/Ganciclovir/*administration & dosage

• Source: Gene therapy [Gene Ther] 2011 Jan; Vol. 18 (1), pp. 73-81. Date of Electronic Publication: 2010 Aug 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A 'Dual' Cell-Level Systems PK-PD Model to Characterize the Bystander Effect of ADC

• Authors : Dhaval K. Shah; Aman P. Singh

Subjects: Immunoconjugates; Antibodies, Monoclonal; Antineoplastic Agents

• Source: Journal of Pharmaceutical Sciences. 108:2465-2475

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An Intratumor Pharmacokinetic/Pharmacodynamic Model for the Hypoxia-Activated Prodrug Evofosfamide (TH-302): Monotherapy Activity is Not Dependent on a Bystander Effect

• Authors : Kevin O. Hicks; Cho R. Hong; William R. Wilson

Subjects: 0301 basic medicine; Original article; Cell Culture Techniques

• Source: NeoplasiaNeoplasia: An International Journal for Oncology Research, Vol 21, Iss 2, Pp 159-171 (2019)

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Adenoviral-mediated interferon alpha overcomes resistance to the interferon protein in various cancer types and has marked bystander effects.

• Authors : Zhang X; Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Yang Z

Subjects: Bystander Effect*; Adenoviridae/Adenoviridae/Adenoviridae/*genetics ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

• Source: Cancer gene therapy [Cancer Gene Ther] 2007 Mar; Vol. 14 (3), pp. 241-50. Date of Electronic Publication: 2006 Nov 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.

• Authors : Helsby NA; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.; Ferry DM

Subjects: Bystander Effect* ; Genetic Therapy*; Aniline Mustard/Aniline Mustard/Aniline Mustard/*analogs & derivatives

• Source: British journal of cancer [Br J Cancer] 2004 Mar 08; Vol. 90 (5), pp. 1084-92.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print Cited Medium:

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Quantitative characterization of in vitro bystander effect of antibody-drug conjugates

• Authors : Aman P. Singh; Dhaval K. Shah; Sharad Sharma

Subjects: Immunoconjugates; Time Factors; Cell Survival

• Source: Journal of Pharmacokinetics and Pharmacodynamics. 43:567-582

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Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase.

• Authors : Evrard A; Laboratoire de Toxicologie du Médicament, Faculté de Pharmacie, Montpellier, France.; Cuq P

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Cell Survival/Cell Survival/Cell Survival/*drug effects ; Floxuridine/Floxuridine/Floxuridine/*toxicity

• Source: British journal of cancer [Br J Cancer] 1999 Aug; Vol. 80 (11), pp. 1726-33.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print Cited Medium:

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Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells

• Authors : Yunhui Liu; Haoqiang Ying; Peixin Sun

Subjects: 0301 basic medicine; Cell Survival; Gossypol

• Source: Oncology Reports. 28:969-976

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A chemotherapy-associated senescence bystander effect in breast cancer cells

• Authors : Lynne W. Elmore; Shawn E. Holt; Xu Di

Subjects: Cyclin-Dependent Kinase Inhibitor p21; 0303 health sciences; Antineoplastic Agents

• Source: Cancer Biology & Therapy. 7:864-872

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ADME and DMPK considerations for the discovery and development of antibody drug conjugates (ADCs).

• Authors : Beaumont, Kevin¹ (AUTHOR); Pike, Andy¹ (AUTHOR); Davies, Michael¹ (AUTHOR)

• Source: Xenobiotica. Aug2022, Vol. 52 Issue 8, p770-785. 16p.

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