نتائج البحث

The cellular prion protein does not affect tau seeding and spreading of sarkosyl-insoluble fractions from Alzheimer's disease.

• Authors : Sala-Jarque J; Molecular and Cellular Neurobiotechnology, Institute for Bioengineering of Catalonia (IBEC), Parc Científic de Barcelona, Baldiri and Reixac 15-21, 08028, Barcelona, Spain.; Department of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain.

Subjects: tau Proteins*/tau Proteins*/tau Proteins*/metabolism ; tau Proteins*/tau Proteins*/tau Proteins*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

• Source: Scientific reports [Sci Rep] 2024 Sep 16; Vol. 14 (1), pp. 21622. Date of Electronic Publication: 2024 Sep 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer's Disease Brains.

• Authors : Soto-Rojas LO; Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, México City 54090, Mexico.; Campa-Córdoba BB

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Astrocytes/Astrocytes/Astrocytes/*pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain.

• Authors : Schlegel K; Neuroscience Discovery, AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061, Ludwigshafen, Germany.; Awwad K

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Brain/Brain/Brain/*metabolism ; Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*metabolism

• Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Nov 13; Vol. 7 (1), pp. 177. Date of Electronic Publication: 2019 Nov 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Amphiphilic Distyrylbenzene Derivatives as Potential Therapeutic and Imaging Agents for Soluble and Insoluble Amyloid β Aggregates in Alzheimer’s Disease

• Authors : Soumyo Sen; Nilantha Bandara; Buck E. Rogers

Subjects: 0301 basic medicine; Amyloid; Chemical Sciences not elsewhere classified

• Source: Journal of the American Chemical Society. 143:10462-10476

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Oxidative balance in Alzheimer's disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β.

• Authors : Tayler H; Dementia Research Group, Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK.; Fraser T

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*genetics

• Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2010; Vol. 22 (4), pp. 1363-73.Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print Cited Medium: Internet ISSN:

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Solving the insoluble.

• Authors : Perry G; Institute of Pathology, Case Western Reserve University, Cleveland, OH, USA.

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*physiopathology ; Brain/Brain/Brain/*pathology

• Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2006; Vol. 9 (3 Suppl), pp. 301-4.Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print Cited Medium: Print ISSN: 1387-2877

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The interaction of insoluble Amyloid‐β with soluble Amyloid‐β dimers decreases Amyloid‐β plaque numbers

• Authors : Else F. van Gerresheim; Arne Herring; Lothar Gremer

Subjects: Amyloid beta-Peptides; Medizin; Brain

• Source: Neuropathology & applied neurobiology 47(5), 603-610 (2021). doi:10.1111/nan.12685

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Insoluble problem?

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*therapy ; Alzheimer Vaccines/Alzheimer Vaccines/Alzheimer Vaccines/*adverse effects ; Alzheimer Vaccines/Alzheimer Vaccines/Alzheimer Vaccines/*therapeutic use

• Source: Nature medicine [Nat Med] 2002 Mar; Vol. 8 (3), pp. 191.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Print ISSN:

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Dissecting Detergent-Insoluble Proteome in Alzheimer's Disease by TMTc-Corrected Quantitative Mass Spectrometry

• Authors : Masihuz Zaman; Yingxue Fu; Ping-Chung Chen

Subjects: Proteomics; Proteome; Alzheimer Disease

• Source: Mol Cell Proteomics

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Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer’s disease

• Authors : David J. Koss; Marina Dubini; Heather Buchanan ...

Subjects: Male; Detergents; tau Proteins

• Source: Brain Research. 1699:121-134

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