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النتائج لكل صفحة: 10

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Academic Journal

A Bayesian Approach to Compare Accumulating Survival Data From Clinical Practice With RCT Data: A Case Study in Non‐Small Cell Lung Cancer Patients: A Case Study in Non-Small Cell Lung Cancer Patients

Authors : Marjon V. Verschueren; Daniel V. Verschueren; Ewoudt M. W. van de Garde

Subjects: Science & Technology; Lung Neoplasms; Research

Source: CPT Pharmacometrics Syst Pharmacol

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Academic Journal

Predicting Systemic and Liver Bosentan Exposure Using Physiologically‐Based Pharmacokinetic Modeling

Authors : Miao‐Chan Huang; Julia Macente; Sofie Heylen

Subjects: Male; Adult; RECEPTOR ANTAGONIST BOSENTAN

Source: CPT Pharmacometrics Syst Pharmacol

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Academic Journal

Predicting Drug Transfer Into Human Milk With the Simcyp Simulator: A Contribution From the ConcePTION Project: A Contribution From the ConcePTION Project

Authors : Julia Macente; Nina Nauwelaerts; Justine Marine Badée

Subjects: perinatal pharmacology; PHARMACOKINETICS; breastfeeding

Source: CPT Pharmacometrics Syst Pharmacol

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Academic Journal

A Multiple Imputation Workflow for Handling Missing Covariate Data in Pharmacometrics Modeling

Authors : Vuong, My-Luong; Verbeke, Geert; Dreesen, Erwin

Subjects: Male; bias; 3214 Pharmacology and pharmaceutical sciences

Source: CPT Pharmacometrics Syst PharmacolCPT: Pharmacometrics & Systems Pharmacology, Vol 14, Iss 6, Pp 991-1005 (2025)

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Academic Journal

Harnessing Open‐Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference

Authors : André Dallmann; Denise Feick; Pavel Balazki

Subjects: Pharmacology; Science & Technology; Systems Biology

Source: CPT Pharmacometrics Syst PharmacolCPT: Pharmacometrics & Systems Pharmacology, Vol 14, Iss 5, Pp 822-827 (2025)

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Academic Journal

The Lipidomic Profile Discriminates Between MASLD and MetALD

Authors : Schneider, Kai Markus; Cao, Feng; Huang, Helen Ye Rim

Subjects: Magnetic Resonance Imaging (mesh); Male; Alcohol Use and Health (rcdc)

Source: Aliment Pharmacol TherAlimentary pharmacology and therapeuticsAlimentary Pharmacology & Therapeutics, vol 61, iss 8

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Academic Journal

Insight into structural properties of viral G protein‐coupled receptors and their role in the viral infection: IUPHAR Review 41

Authors : Tsutsumi, Naotaka; Kildedal, Dagmar Faester; Hansen, Olivia Kramer

Subjects: NF-KAPPA-B; INHIBITION; 3214 Pharmacology and pharmaceutical sciences

Source: Tsutsumi, N, Kildedal, D F, Hansen, O K, Kong, Q, Schols, D, Van Loy, T & Rosenkilde, M M 2025, ' Insight into structural properties of viral G protein-coupled receptors and their role in the viral

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Academic Journal

PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism?

Authors : Justine Henriot; André Dallmann; François Dupuis

Subjects: PROTEIN EXPRESSION; IMPACT; Midazolam

Source: CPT Pharmacometrics Syst PharmacolCPT: Pharmacometrics & Systems Pharmacology, Vol 14, Iss 1, Pp 130-141 (2025)

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Academic Journal

Long‐term safety and efficacy of filgotinib for the treatment of moderately to severely active ulcerative colitis: Interim analysis from up to 4 years of follow‐up in the SELECTION open‐label long‐term extension study

Authors : Feagan, Brian G.; Matsuoka, Katsuyoshi; Rogler, Gerhard ...

Subjects: Male; Adult; Pyridines

Source: Alimentary Pharmacology & Therapeutics. 60:563-584

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Academic Journal

Efficacy and safety of risankizumab by baseline corticosteroid use and achievement of corticosteroid‐free clinical and endoscopic outcomes in patients with moderately to severely active Crohn's disease

Authors : Stefan Schreiber; Raymond K. Cross; Remo Panaccione

Subjects: Male; Adult; Prednisone/therapeutic use/administration & dosage

Source: Alimentary Pharmacology & Therapeutics. 60:897-906

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