نتائج البحث

Personalised regional modelling predicts tau progression in the human brain.

• Authors : Pavanjit Chaggar; Jacob W Vogel; Alexa Pichet Binette

Subjects: Biology (General); QH301-705.5

• Source: PLoS Biology, Vol 23, Iss 7, p e3003241 (2025)

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Structural exposure of different microtubule binding domains determines the propagation and toxicity of pathogenic tau conformers in Alzheimer's disease.

• Authors : Lenka Hromadkova; Chae Kim; Tracy Haldiman

Subjects: Immunologic diseases. Allergy; RC581-607; Biology (General)

• Source: PLoS Pathogens, Vol 21, Iss 6, p e1012926 (2025)

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Klotho null mutation leads to retinal degeneration characterized by functional impairment, gliosis, and deposition of amyloid-beta and hyperphosphorylated tau proteins

• Authors : Zhi-Jia Chen; Chun-Yen Wu; Fang-Yan Hsiao

Subjects: Male; Amyloid beta-Peptides; Science

• Source: PLoS OnePLoS ONE, Vol 20, Iss 5, p e0323633 (2025)

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The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons

• Authors : Policarpo, Rafaela; Wolfs, Leen; Martinez-Montero, Saul

Subjects: Science & Technology; Multidisciplinary Sciences; Science & Technology - Other Topics

• Source: ISSN:1932-6203 ; Plos One, vol. 20 (1), Art.No. ARTN e0314973.

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Structural exposure of different microtubule binding domains determines the propagation and toxicity of pathogenic tau conformers in Alzheimer’s disease

• Authors : Hromadkova, Lenka; Kim, Chae; Haldiman, Tracy ...

• Source: PLoS Pathogens , 21 (6) , Article e1012926. (2025)

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SARS-CoV-2 propagation to the TPH2-positive neurons in the ventral tegmental area induces cell death via GSK3β-dependent accumulation of phosphorylated tau

• Authors : Motoki Imai; Fumitaka Kawakami; Takayuki Uematsu

Subjects: Neurons; Male; Glycogen Synthase Kinase 3 beta

• Source: PLoS OnePLoS ONE, Vol 19, Iss 10, p e0312834 (2024)

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Tau protein aggregation associated with SARS-CoV-2 main protease

• Authors : Raphael Josef Eberle; Mônika Aparecida Coronado; Ian Gering

Subjects: SARS-CoV-2; Science; COVID-19

• Source: PLoS OnePLoS ONE, Vol 18, Iss 8 (2023)PLoS ONE, Vol 18, Iss 8, p e0288138 (2023)PLOS ONE 18(8), e0288138-(2023). doi:10.1371/journal.pone.0288138

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Clostridium butyricum improves cognitive dysfunction in ICV-STZ-induced Alzheimer’s disease mice via suppressing TLR4 signaling pathway through the gut-brain axis

• Authors : Yunfang Su; Dahui Wang; Ningning Liu

Subjects: Science; NF-kappa B; tau Proteins

• Source: PLoS OnePLoS ONE, Vol 18, Iss 6, p e0286086 (2023)

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Development of a cell-free screening assay for the identification of direct PERK activators

• Authors : Márcia F. D. Costa; Günter U. Höglinger; Thomas W. Rösler

Subjects: genetics [eIF-2 Kinase]; Science; Eukaryotic Initiation Factor-2

• Source: PLoS OnePLoS ONE, Vol 18, Iss 5, p e0283943 (2023)PLOS ONE 18(5), e0283943 (2023). doi:10.1371/journal.pone.0283943

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A seeding-based neuronal model of tau aggregation for use in drug discovery

• Authors : Amorim, Ines; Challal, Sylvie; Cistarelli, Laetitia ...

Subjects: Neurons; [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology; [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology

• Source: PLoS OnePLoS ONE, Vol 18, Iss 4, p e0283941 (2023)

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