نتائج البحث

The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir.

• Authors : Huang SW; Division of Infectious Diseases, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, Colorado, United States of America.; Briganti L

Subjects: Anti-HIV Agents*/Anti-HIV Agents*/Anti-HIV Agents*/pharmacology ; HIV-1*/HIV-1*/HIV-1*/drug effects ; HIV-1*/HIV-1*/HIV-1*/physiology

• Source: PLoS pathogens [PLoS Pathog] 2025 Jan 27; Vol. 21 (1), pp. e1012862. Date of Electronic Publication: 2025 Jan 27 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection

تفاصيل العنوان

Vorolanib, sunitinib, and axitinib: A comparative study of vascular endothelial growth factor receptor inhibitors and their anti-angiogenic effects.

• Authors : Bakri SJ; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America.; Lynch J

Subjects: Axitinib*/Axitinib*/Axitinib*/pharmacology ; Sunitinib*/Sunitinib*/Sunitinib*/pharmacology ; Angiogenesis Inhibitors*/Angiogenesis Inhibitors*/Angiogenesis Inhibitors*/pharmacology

• Source: PloS one [PLoS One] 2024 Jun 04; Vol. 19 (6), pp. e0304782. Date of Electronic Publication: 2024 Jun 04 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

Evaluation of the antiproliferative effects of the HASPIN inhibitor CHR-6494 in breast cancer cell lines.

• Authors : Nishida-Fukuda H; Department of Genome Editing, Institute of Biomedical Science, Kansai Medical University, Hirakata City, Osaka, Japan.; Tokuhiro K

Subjects: Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Indazoles/Indazoles/Indazoles/*pharmacology ; Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/*antagonists & inhibitors

• Source: PloS one [PLoS One] 2021 Apr 14; Vol. 16 (4), pp. e0249912. Date of Electronic Publication: 2021 Apr 14 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.

• Authors : Lauwaet T; Department of Pathology, University of California, San Diego, La Jolla, California, United States of America.; Miyamoto Y

Subjects: Antiparasitic Agents/Antiparasitic Agents/Antiparasitic Agents/*pharmacology ; Click Chemistry/Click Chemistry/Click Chemistry/*methods ; Drug Discovery/Drug Discovery/Drug Discovery/*methods

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Apr 17; Vol. 14 (4), pp. e0008224. Date of Electronic Publication: 2020 Apr 17 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection

تفاصيل العنوان

A SONAR report on Nirmatrelvir/ritonavir-associated rebound COVID-19: Using new databases for evaluating new diseases.

• Authors : Bennett CL; Department of Southern Network on Adverse Reactions (SONAR), University of South Carolina, Columbia, South Carolina, United States of America.; Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina, Columbia, South Carolina, United States of America.

Subjects: Ritonavir*/Ritonavir*/Ritonavir*/therapeutic use ; Ritonavir*/Ritonavir*/Ritonavir*/adverse effects ; COVID-19 Drug Treatment*

• Source: PloS one [PLoS One] 2024 Sep 25; Vol. 19 (9), pp. e0308205. Date of Electronic Publication: 2024 Sep 25 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo.

• Authors : Ihn HJ; Department of Oral Pathology and Regenerative Medicine, School of Dentistry, IHBR, Kyungpook National University, Daegu, Republic of Korea.; Lee T

Subjects: Alveolar Bone Loss/Alveolar Bone Loss/Alveolar Bone Loss/*drug therapy ; Bone Resorption/Bone Resorption/Bone Resorption/*drug therapy ; Indazoles/Indazoles/Indazoles/*pharmacology

• Source: PloS one [PLoS One] 2017 Jan 13; Vol. 12 (1), pp. e0170159. Date of Electronic Publication: 2017 Jan 13 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

Spectrophotometric and molecular modelling studies on in vitro interaction of tyrosine kinase inhibitor linifanib with bovine serum albumin.

• Authors : Wani TA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Bakheit AH

Subjects: Indazoles/Indazoles/Indazoles/*metabolism ; Phenylurea Compounds/Phenylurea Compounds/Phenylurea Compounds/*metabolism ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*metabolism

• Source: PloS one [PLoS One] 2017 Apr 18; Vol. 12 (4), pp. e0176015. Date of Electronic Publication: 2017 Apr 18 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

Correction: Suprafenacine, an Indazole-Hydrazide Agent, Targets Cancer Cells Through Microtubule Destabilization.

• Authors : Choi, Bo-Hwa; Chattopadhaya, Souvik; Thanh, Le Nguyen

• Source: PLoS ONE. 7/18/2018, Vol. 13 Issue 7, p1-3. 3p.

تفاصيل العنوان

Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455.

• Authors : Wu D; Laboratory of Structural Biology, Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, XiangYa Hospital, Central South University, Changsha, Hunan 410008, China.; Guo M

Subjects: Indazoles/Indazoles/Indazoles/*metabolism ; Receptor, Fibroblast Growth Factor, Type 4/Receptor, Fibroblast Growth Factor, Type 4/Receptor, Fibroblast Growth Factor, Type 4/*metabolism; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/metabolism

• Source: PloS one [PLoS One] 2016 Sep 12; Vol. 11 (9), pp. e0162491. Date of Electronic Publication: 2016 Sep 12 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان

Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization.

• Authors : Choi BH; Division of Structural Biology and Biochemistry, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; Chattopadhaya S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Hydrazines/Hydrazines/Hydrazines/*pharmacology ; Indazoles/Indazoles/Indazoles/*pharmacology

• Source: PloS one [PLoS One] 2014 Oct 29; Vol. 9 (10), pp. e110955. Date of Electronic Publication: 2014 Oct 29 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

تفاصيل العنوان