نتائج البحث

The "DDVF" motif used by viral and bacterial proteins to hijack RSK kinases mimics a short linear motif (SLiM) found in proteins related to the RAS-ERK MAP kinase pathway.

• Authors : Veinstein, Martin¹ (AUTHOR); Stroobant, Vincent² (AUTHOR); Wavreil, Fanny¹ (AUTHOR)

• Source: PLoS Pathogens. 3/28/2025, Vol. 21 Issue 3, p1-20. 20p.

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Surface protein glycosylation conserved in the human pathogen Mycoplasma genitalium and retained in the synthetic organism JCVI-Syn3A.

• Authors : Sanford JW; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Mobley J

Subjects: Mycoplasma genitalium*/Mycoplasma genitalium*/Mycoplasma genitalium*/metabolism ; Mycoplasma genitalium*/Mycoplasma genitalium*/Mycoplasma genitalium*/genetics ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/metabolism

• Source: PloS one [PLoS One] 2025 Sep 22; Vol. 20 (9), pp. e0329506. Date of Electronic Publication: 2025 Sep 22 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Identification and 3D modeling of bioactive peptides from Lactobacillus brevis RAMULAB49 protein hydrolysate with in silico ERK1 phosphorylation inhibition activity targeting diabetic nephropathy.

• Authors : Martiz RM; Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education & Research, Mysore, Karnataka, India.; Department of Microbiology, JSS Academy of Higher Education & Research, Mysore, Karnataka, India.

Subjects: Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/drug therapy ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/metabolism ; Levilactobacillus brevis*/Levilactobacillus brevis*/Levilactobacillus brevis*/metabolism

• Source: PloS one [PLoS One] 2025 Sep 22; Vol. 20 (9), pp. e0331192. Date of Electronic Publication: 2025 Sep 22 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Regulation of host immunity by a novel Legionella pneumophila E3 ubiquitin ligase.

• Authors : Liu S; Department of Respiratory Medicine, Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, The First Hospital of Jilin University, Changchun, China.; He C

Subjects: Legionella pneumophila*/Legionella pneumophila*/Legionella pneumophila*/immunology ; Legionella pneumophila*/Legionella pneumophila*/Legionella pneumophila*/enzymology ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism

• Source: PLoS pathogens [PLoS Pathog] 2025 Sep 15; Vol. 21 (9), pp. e1013522. Date of Electronic Publication: 2025 Sep 15 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection

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Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase.

• Authors : Trebino MA; Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, United States of America.; Kitts G

Subjects: Biofilms*/Biofilms*/Biofilms*/growth & development ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/analogs & derivatives ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism

• Source: PLoS genetics [PLoS Genet] 2025 Sep 15; Vol. 21 (9), pp. e1011870. Date of Electronic Publication: 2025 Sep 15 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection

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Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis.

• Authors : Gardiner S; Department of Physics and Astronomy, Brigham Young University, Provo, Utah, United States of America.; Dollinger P

Subjects: Lipase*/Lipase*/Lipase*/chemistry ; Lipase*/Lipase*/Lipase*/genetics ; Lipase*/Lipase*/Lipase*/metabolism

• Source: PloS one [PLoS One] 2025 Sep 12; Vol. 20 (9), pp. e0332409. Date of Electronic Publication: 2025 Sep 12 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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The type III secretion system translocases IpaC, SipC, and BipC are partially folded alpha helical proteins lacking in tertiary structures.

• Authors : Kroh JM; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas United States of America.; Chakravarty A

Subjects: Type III Secretion Systems*/Type III Secretion Systems*/Type III Secretion Systems*/chemistry ; Type III Secretion Systems*/Type III Secretion Systems*/Type III Secretion Systems*/metabolism ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/chemistry

• Source: PloS one [PLoS One] 2025 Sep 12; Vol. 20 (9), pp. e0331455. Date of Electronic Publication: 2025 Sep 12 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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The Salmonella phage shock protein system is required for defense against host antimicrobial peptides.

• Authors : Massicotte MA; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.

Subjects: Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/immunology ; Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/genetics ; Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/metabolism

• Source: PLoS pathogens [PLoS Pathog] 2025 Sep 09; Vol. 21 (9), pp. e1013132. Date of Electronic Publication: 2025 Sep 09 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection

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Cell splitting in Staphylococcus aureus is controlled by an adaptor protein facilitating degradation of a peptidoglycan hydrolase.

• Authors : Barbuti MD; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.; Skjennum EF

Subjects: Staphylococcus aureus*/Staphylococcus aureus*/Staphylococcus aureus*/genetics ; Staphylococcus aureus*/Staphylococcus aureus*/Staphylococcus aureus*/drug effects ; Staphylococcus aureus*/Staphylococcus aureus*/Staphylococcus aureus*/metabolism

• Source: PLoS genetics [PLoS Genet] 2025 Sep 05; Vol. 21 (9), pp. e1011841. Date of Electronic Publication: 2025 Sep 05 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection

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Structure-function studies of Vibrio cholerae quorum-sensing receptor CqsR signal recognition.

• Authors : Guarnaccia AM; Department of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, United States of America.; Steenhaut AD

Subjects: Vibrio cholerae*/Vibrio cholerae*/Vibrio cholerae*/metabolism ; Vibrio cholerae*/Vibrio cholerae*/Vibrio cholerae*/physiology ; Quorum Sensing*/Quorum Sensing*/Quorum Sensing*/physiology

• Source: PLoS pathogens [PLoS Pathog] 2025 Sep 04; Vol. 21 (9), pp. e1013447. Date of Electronic Publication: 2025 Sep 04 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection

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