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Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health; Journal Article

  • Source: Carter, Bing Z; Mak, Po Yee; Tao, Wenjing; Ayoub, Edward; Ostermann, Lauren B; Huang, Xuelin; Loghavi, Sanam; Boettcher, Steffen; Nishida, Yuki; Ruvolo, Vivian; Hughes, Paul E; Morrow, Phuong K;

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Academic Journal

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health

  • Source: Carter, Bing Z; Mak, Po Yee; Tao, Wenjing; Ayoub, Edward; Ostermann, Lauren B; Huang, Xuelin; Loghavi, Sanam; Boettcher, Steffen; Nishida, Yuki; Ruvolo, Vivian; Hughes, Paul E; Morrow, Phuong K;

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Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

  • Source: Scientific reports [Sci Rep] 2019 Mar 12; Vol. 9 (1), pp. 4672. Date of Electronic Publication: 2019 Mar 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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  • 1-10 ل  94 نتائج ل ""combined inhibition""