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Academic Journal

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway.

Authors : Tung NTC; Department of Trauma and Orthopaedic Surgery, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam. .; Department of Orthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan. .

Subjects: Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/metabolism ; Cell Differentiation* ; Myofibroblasts*/Myofibroblasts*/Myofibroblasts*/metabolism

Source: Scientific reports [Sci Rep] 2025 Jul 15; Vol. 15 (1), pp. 25505. Date of Electronic Publication: 2025 Jul 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Downregulation of DNA methylation enhances differentiation of THP-1 cells and induces M1 polarization of differentiated macrophages.

Authors : Park J; Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, 06974, Republic of Korea.; Luo Y

Subjects: DNA Methylation* ; DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/genetics ; DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/metabolism

Source: Scientific reports [Sci Rep] 2023 Aug 12; Vol. 13 (1), pp. 13132. Date of Electronic Publication: 2023 Aug 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

DUSP1 mediates BCG induced apoptosis and inflammatory response in THP-1 cells via MAPKs/NF-κB signaling pathway.

Authors : Liu Z; Key Lab of Ministry of Education for Protection and Utilization of Special Biological Resources in Western China, Yinchuan, 750021, Ningxia, China.; School of Life Sciences, Ningxia University, 539 W. Helanshan Road, Yinchuan, 750021, Ningxia, China.

Subjects: Mycobacterium bovis* ; Tuberculosis*/Tuberculosis*/Tuberculosis*/metabolism; Humans

Source: Scientific reports [Sci Rep] 2023 Feb 14; Vol. 13 (1), pp. 2606. Date of Electronic Publication: 2023 Feb 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells.

Authors : Sakamaki I; Department of Infectious Diseases, Faculty of Medical Sciences, University of Fukui, 23-3, Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan. .; Fukushi M

Subjects: ADAM17 Protein/ADAM17 Protein/ADAM17 Protein/*metabolism ; Fluoroquinolones/Fluoroquinolones/Fluoroquinolones/*pharmacology ; Lipopolysaccharides/Lipopolysaccharides/Lipopolysaccharides/*toxicity

Source: Scientific reports [Sci Rep] 2021 Dec 17; Vol. 11 (1), pp. 24154. Date of Electronic Publication: 2021 Dec 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

P 2 Y 12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells.

Authors : Siegel PM; Department of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.

Subjects: Acute Coronary Syndrome/Acute Coronary Syndrome/Acute Coronary Syndrome/*pathology ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Coronary Artery Disease/Coronary Artery Disease/Coronary Artery Disease/*pathology

Source: Scientific reports [Sci Rep] 2021 Aug 31; Vol. 11 (1), pp. 17459. Date of Electronic Publication: 2021 Aug 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Studying dynamic stress effects on the behaviour of THP-1 cells by microfluidic channels.

Authors : Birol SZ; Department of Nanoscience and Nanoengineering, Istanbul Technical University, 34469, Istanbul, Turkey. .; Nanotechnology Research and Application Center-ITUnano, Istanbul Technical University, 34469, Istanbul, Turkey. .

Subjects: Lab-On-A-Chip Devices* ; Microfluidics*; Plaque, Atherosclerotic/Plaque, Atherosclerotic/Plaque, Atherosclerotic/*physiopathology

Source: Scientific reports [Sci Rep] 2021 Jul 13; Vol. 11 (1), pp. 14379. Date of Electronic Publication: 2021 Jul 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells.

Authors : Lindner B; Department of Drug Discovery Science, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorferstr. 65, 88397, Biberach an der Riss, Germany. .; Martin E

Subjects: CRISPR-Cas Systems* ; Genome-Wide Association Study*/Genome-Wide Association Study*/Genome-Wide Association Study*/methods; Monocytes/Monocytes/Monocytes/*immunology

Source: Scientific reports [Sci Rep] 2021 Jun 21; Vol. 11 (1), pp. 12973. Date of Electronic Publication: 2021 Jun 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Exploring circulating cell-free DNA as a biomarker and as an inducer of AIM2-inflammasome-mediated inflammation in patients with abdominal aortic aneurysm.

Authors : Dihlmann S; Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany. .; Kaduk C

Subjects: Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/blood ; Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/pathology ; Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/Aortic Aneurysm, Abdominal*/genetics

Source: Scientific reports [Sci Rep] 2025 Jun 20; Vol. 15 (1), pp. 20196. Date of Electronic Publication: 2025 Jun 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

HSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells.

Authors : Venuti A; Department of Chemical Biological Pharmaceutical and Environmental Sciences, University of Messina, Viale F, Stagno d'Alcontres, 31, Messina, 98166, Italy. .; Infections and Cancer Biology Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon, France. .

Subjects: Herpesvirus 1, Human/Herpesvirus 1, Human/Herpesvirus 1, Human/*physiology ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism ; Monocytes/Monocytes/Monocytes/*metabolism

Source: Scientific reports [Sci Rep] 2019 Mar 26; Vol. 9 (1), pp. 5157. Date of Electronic Publication: 2019 Mar 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Vitamin D and lipopolysaccharide jointly induce a distinct epigenetic and transcriptional program in human monocytes.

Authors : Jankowski M; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, Olsztyn, 10-683, Poland.; Hämäläinen E

Subjects: Monocytes*/Monocytes*/Monocytes*/drug effects ; Monocytes*/Monocytes*/Monocytes*/metabolism ; Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/pharmacology

Source: Scientific reports [Sci Rep] 2025 Jul 28; Vol. 15 (1), pp. 27480. Date of Electronic Publication: 2025 Jul 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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نتائج البحث

فلترة النتائج

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway.

Downregulation of DNA methylation enhances differentiation of THP-1 cells and induces M1 polarization of differentiated macrophages.

DUSP1 mediates BCG induced apoptosis and inflammatory response in THP-1 cells via MAPKs/NF-κB signaling pathway.

Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells.

P 2 Y 12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells.

Studying dynamic stress effects on the behaviour of THP-1 cells by microfluidic channels.

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells.

Exploring circulating cell-free DNA as a biomarker and as an inducer of AIM2-inflammasome-mediated inflammation in patients with abdominal aortic aneurysm.

HSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells.

Vitamin D and lipopolysaccharide jointly induce a distinct epigenetic and transcriptional program in human monocytes.

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