Authors : Kim J; Department of Biological Sciences, Seoul National University, Seoul, 08826, Republic of Korea.; Division of Biological Science and Technology, Yonsei University, Wonju, 26493, Republic of Korea.

Subjects: Receptors, Complement*/Receptors, Complement*/Receptors, Complement*/chemistry ; Receptors, Complement*/Receptors, Complement*/Receptors, Complement*/metabolism ; Receptors, Complement*/Receptors, Complement*/Receptors, Complement*/agonists

Source: The EMBO journal [EMBO J] 2025 May; Vol. 44 (10), pp. 2803-2826. Date of Electronic Publication: 2025 Apr 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway.

Authors : Turner NA; Department of Bioengineering, Rice University, Houston, TX, USA. .; Moake JL

Subjects: Complement Factor H*/Complement Factor H*/Complement Factor H*/metabolism ; Complement Pathway, Alternative* ; Complement Factor I*/Complement Factor I*/Complement Factor I*/metabolism

Source: Scientific reports [Sci Rep] 2025 Mar 29; Vol. 15 (1), pp. 10883. Date of Electronic Publication: 2025 Mar 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Inhibition of the complement component C5 and the Toll-like receptor molecule CD14 prevents systemic and local kidney inflammation in mice experiencing brain death.

Authors : Mollnes TE; Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway. .; Research Laboratory, Nordland Hospital Trust, Bodø, Norway. .

Subjects: Lipopolysaccharide Receptors*/Lipopolysaccharide Receptors*/Lipopolysaccharide Receptors*/antagonists & inhibitors ; Lipopolysaccharide Receptors*/Lipopolysaccharide Receptors*/Lipopolysaccharide Receptors*/metabolism ; Complement C5*/Complement C5*/Complement C5*/antagonists & inhibitors

Source: Scientific reports [Sci Rep] 2025 Jul 25; Vol. 15 (1), pp. 27018. Date of Electronic Publication: 2025 Jul 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Genetic susceptibility to cerebral palsy involves complement system-mediated neuronal development and plasticity pathway.

Authors : Kun H; Department of Neurology, The First People's Hospital of Fuzhou, Fuzhou, Jiangxi, China.; Zhou Q

Subjects: Cerebral Palsy*/Cerebral Palsy*/Cerebral Palsy*/genetics ; Genetic Predisposition to Disease* ; Neuronal Plasticity*/Neuronal Plasticity*/Neuronal Plasticity*/genetics

Source: Scientific reports [Sci Rep] 2025 Jul 02; Vol. 15 (1), pp. 23088. Date of Electronic Publication: 2025 Jul 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation.

Authors : Banda NK; Moreland LW ...

Subjects: Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/genetics ; Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/metabolism ; Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/pathology

Source: Scientific reports [Sci Rep] 2025 Jun 04; Vol. 15 (1), pp. 19633. Date of Electronic Publication: 2025 Jun 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies.

Authors : Yang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No.1 East Jianshe Road, Erqi District, Zhengzhou, 450052, China.; Zhang Y

Subjects: Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/metabolism ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/pathology ; Proteomics*/Proteomics*/Proteomics*/methods

Source: Scientific reports [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 495. Date of Electronic Publication: 2025 Jan 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation.

Authors : Azamor T; Infection Biology Program, Global Center for Pathogen Research and Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; Familiar-Macedo D

Subjects: Complement C1q*/Complement C1q*/Complement C1q*/metabolism ; Complement C1q*/Complement C1q*/Complement C1q*/genetics ; COVID-19*/COVID-19*/COVID-19*/virology

Source: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (22), pp. 5494-5529. Date of Electronic Publication: 2024 Oct 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Academic Journal

Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases.

Authors : Xiao M; Institute of Nephrology and Blood Purification, The First Affiliated Hospital of Jinan University, Guangzhou, China.; Chi X

Subjects: Complement Activation* ; Proteomics*/Proteomics*/Proteomics*/methods ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

Source: Scientific reports [Sci Rep] 2024 Aug 20; Vol. 14 (1), pp. 19311. Date of Electronic Publication: 2024 Aug 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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Academic Journal

A bipartite bacterial virulence factor targets the complement system and neutrophil activation.

Authors : Kurniyati K; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA.; Clark ND

Subjects: Virulence Factors*/Virulence Factors*/Virulence Factors*/metabolism ; Virulence Factors*/Virulence Factors*/Virulence Factors*/genetics ; Virulence Factors*/Virulence Factors*/Virulence Factors*/immunology

Source: The EMBO journal [EMBO J] 2025 Feb; Vol. 44 (4), pp. 1154-1184. Date of Electronic Publication: 2025 Jan 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited

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Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study.

Authors : Pinzon-Hoyos N; Department of Biological Sciences, Dedman College of Humanities & Science, Southern Methodist University, 6501 Airline Rd, Dallas, TX, 75205, USA.; Li Y

Subjects: Cytokines*/Cytokines*/Cytokines*/blood ; Drug Resistant Epilepsy*/Drug Resistant Epilepsy*/Drug Resistant Epilepsy*/blood ; Drug Resistant Epilepsy*/Drug Resistant Epilepsy*/Drug Resistant Epilepsy*/immunology

Source: Scientific reports [Sci Rep] 2025 Feb 11; Vol. 15 (1), pp. 5096. Date of Electronic Publication: 2025 Feb 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited

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نتائج البحث

فلترة النتائج

Structural insights into small-molecule agonist recognition and activation of complement receptor C3aR.

The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway.

Inhibition of the complement component C5 and the Toll-like receptor molecule CD14 prevents systemic and local kidney inflammation in mice experiencing brain death.

Genetic susceptibility to cerebral palsy involves complement system-mediated neuronal development and plasticity pathway.

Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation.

Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies.

Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation.

Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases.

A bipartite bacterial virulence factor targets the complement system and neutrophil activation.

Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study.

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