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Academic Journal

Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90.

Authors : Turnbull, Emma L.¹; Martin, Ina V.^1,2; Fantes, Peter A.¹

Source: FEBS Journal. Aug2005, Vol. 272 Issue 16, p4129-4140. 12p.

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Heat shock protein 90 (Hsp90) chaperone complex inhibitor, Radicicol, potentiated radiation-induced cell killing in a hormone-sensitive prostate cancer cell line through degradation of the androgen receptor.

Authors : Harashima, K.¹; Akimoto, T.¹ ; Nonaka, T.¹

Source: International Journal of Radiation Biology. Jan2005, Vol. 81 Issue 1, p63-76. 14p.

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.

Authors : Waza, Masahiro¹; Adachi, Hiroaki¹; Katsuno, Masahisa¹

Source: Nature Medicine. Oct2005, Vol. 11 Issue 10, p1088-1095. 8p.

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Human leukemias with mutated FLT3 kinase are synergistically sensitive to FLT3 and Hsp90 inhibitors: the key role of the STAT5 signal transduction pathway.

Authors : Yao, Q.¹; Nishiuchi, R.^1,2; Kitamura, T.³

Source: Leukemia (08876924). Sep2005, Vol. 19 Issue 9, p1605-1612. 8p.

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Academic Journal

Anti-Tumor Antibodies in Ovarian Cancer.

Authors : Luborsky, Judith L.^1,2 ; Barua, Animesh¹; Shatavi, Seerin V.¹

Source: American Journal of Reproductive Immunology. Aug2005, Vol. 54 Issue 2, p55-62. 8p. 1 Chart.

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Synergistic activity of imatinib and 17-AAG in imatinib-resistant CML cells overexpressing BCR-ABL – Inhibition of P-glycoprotein function by 17-AAG.

Authors : Radujkovic, A.¹; Schad, M.¹; Topaly, J.²

Source: Leukemia (08876924). Jul2005, Vol. 19 Issue 7, p1198-1206. 9p.

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Reciprocal changes in endothelium-derived hyperpolarizing factor- and nitric oxide-system in the mesenteric artery of adult female rats following ovariectomy.

Authors : Nawate, Satoshi^1,2; Fukao, Mitsuhiro²; Sakuma, Ichiro¹

Source: British Journal of Pharmacology. Jan2005, Vol. 144 Issue 2, p178-189. 12p.

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Academic Journal

Escort service for cross-priming.

Authors : Melief, Cornelis J. M.¹

Source: Nature Immunology. Jun2005, Vol. 6 Issue 6, p543-544. 2p.

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Academic Journal

A helping hand.

Authors : Owens, Joanna

Source: Nature Reviews Genetics. Nov2005, Vol. 6 Issue 11, p801-801. 1p. 1 Color Photograph.

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Academic Journal

Mycograb®: Human recombinant antibody to HSP90.

Authors : Garg, A.¹ ; Rataholi, P. V.¹

Source: Indian Journal of Pharmacology. Feb2005, Vol. 37 Issue 1, p47-47. 1p.

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فلترة النتائج

Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90.

Heat shock protein 90 (Hsp90) chaperone complex inhibitor, Radicicol, potentiated radiation-induced cell killing in a hormone-sensitive prostate cancer cell line through degradation of the androgen receptor.

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.

Human leukemias with mutated FLT3 kinase are synergistically sensitive to FLT3 and Hsp90 inhibitors: the key role of the STAT5 signal transduction pathway.

Anti-Tumor Antibodies in Ovarian Cancer.

Synergistic activity of imatinib and 17-AAG in imatinib-resistant CML cells overexpressing BCR-ABL – Inhibition of P-glycoprotein function by 17-AAG.

Reciprocal changes in endothelium-derived hyperpolarizing factor- and nitric oxide-system in the mesenteric artery of adult female rats following ovariectomy.

Escort service for cross-priming.

A helping hand.

Mycograb®: Human recombinant antibody to HSP90.

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