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A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS).

• Authors : Ostermann, Marlies¹ (AUTHOR); Corteville, David C.² (AUTHOR); Doi, Kent³ (AUTHOR)

• Source: Trials. 5/30/2025, Vol. 26 Issue 1, p1-11. 11p.

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CompLement C5 Antibodies for decreasing brain injury after aneurysmal Subarachnoid Haemorrhage (CLASH): study protocol for a randomised controlled phase II clinical trial.

• Authors : Koopman I; Rinkel GJE ...

Subjects: Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/drug therapy; Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*therapeutic use ; Brain Ischemia/Brain Ischemia/Brain Ischemia/*prevention & control

• Source: Trials [Trials] 2020 Nov 25; Vol. 21 (1), pp. 969. Date of Electronic Publication: 2020 Nov 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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Efficacy of mistletoe extract as a complement to standard treatment in advanced pancreatic cancer: study protocol for a multicentre, parallel group, double-blind, randomised, placebo-controlled clinical trial (MISTRAL)

• Authors : Kathrin Wode; Johanna Hök Nordberg; Gunver S. Kienle

Subjects: Neoplasms; Pancreatic neoplasms; Mistletoe

• Source: Trials, Vol 21, Iss 1, Pp 1-17 (2020)

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A double-blind randomised controlled investigation into the efficacy of Mirococept (APT070) for preventing ischaemia reperfusion injury in the kidney allograft (EMPIRIKAL): study protocol for a randomised controlled trial.

• Authors : Kassimatis, Theodoros¹; Qasem, Anass¹; Douiri, Abdel²

• Source: Trials. 6/6/2017, Vol. 18, p1-11. 11p. 3 Diagrams, 1 Chart.

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Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19).

• Authors : Urwyler P; Division of Internal Medicine, University Hospital Basel, Basel, Switzerland.; Charitos P

Subjects: COVID-19 Drug Treatment*; Complement C1 Inhibitor Protein/Complement C1 Inhibitor Protein/Complement C1 Inhibitor Protein/*administration & dosage ; SARS-CoV-2/SARS-CoV-2/SARS-CoV-2/*isolation & purification

• Source: Trials [Trials] 2021 Jan 04; Vol. 22 (1), pp. 1. Date of Electronic Publication: 2021 Jan 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial.

• Authors : Smith K; Medical Writing, Alexion Pharmaceuticals, Boston, MA, USA.; Pace A

Subjects: Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*administration & dosage ; Antiviral Agents/Antiviral Agents/Antiviral Agents/*administration & dosage ; Betacoronavirus/Betacoronavirus/Betacoronavirus/*drug effects

• Source: Trials [Trials] 2020 Jul 13; Vol. 21 (1), pp. 639. Date of Electronic Publication: 2020 Jul 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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Evaluation of the efficacy and safety of icatibant and C1 esterase/kallikrein inhibitor in severe COVID-19: study protocol for a three-armed randomized controlled trial.

• Authors : Mansour E; Department of Internal Medicine, School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.; Bueno FF

Subjects: COVID-19 Drug Treatment*; Bradykinin/Bradykinin/Bradykinin/*analogs & derivatives ; Complement C1 Inhibitor Protein/Complement C1 Inhibitor Protein/Complement C1 Inhibitor Protein/*administration & dosage

• Source: Trials [Trials] 2021 Jan 20; Vol. 22 (1), pp. 71. Date of Electronic Publication: 2021 Jan 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial.

• Authors : van Erp, Inge A. M.¹ (AUTHOR) ; van Essen, Thomas A.¹ (AUTHOR); Fluiter, Kees² (AUTHOR)

• Source: Trials. 12/4/2021, Vol. 22 Issue 1, p1-11. 11p. 2 Diagrams, 1 Chart.

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DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial

• Authors : Nginache Nampota-Nkomba; Osward M. Nyirenda; Jane Mallewa

Subjects: Adult; Medicine (General); Alternative medicine

• Source: TrialsTrials, Vol 25, Iss 1, Pp 1-17 (2024)

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Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial

• Authors : Jozefien Declercq; Cedric Bosteels; Karel Van Damme

Subjects: COVID-19; Randomised controlled trial; protocol

• Source: Trials, Vol 21, Iss 1, Pp 1-3 (2020)

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