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Academic Journal

Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3.

  • Authors : Ghosh SK; Molecular Mycopathology Lab, Cancer Research Unit, PG Department of Botany, Ramakrishna Mission Vivekananda Centenary College (Autonomous), Rahara, Kolkata, West Bengal, 700118, India. .; Pandey K

Subjects: Antioxidants*/Antioxidants*/Antioxidants*/pharmacology ; Antioxidants*/Antioxidants*/Antioxidants*/chemistry ; Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Feb 05; Vol. 15 (1), pp. 4313. Date of Electronic Publication: 2025 Feb 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Salidroside ameliorates diabetic amyotrophy by targeting Caspase-3 to inhibit apoptosis.

  • Authors : Wang H; Department of Public Health and Preventive Medicine, Changzhi Medical College, Changzhi, 046000, Shanxi, People's Republic of China.; Shanxi Higher Education Institutions of Science and Technology Innovation Plan Platform, Laboratory of Environmental Factors and Population Health, Changzhi, 046000, China.

Subjects: Glucosides*/Glucosides*/Glucosides*/pharmacology ; Glucosides*/Glucosides*/Glucosides*/chemistry ; Glucosides*/Glucosides*/Glucosides*/therapeutic use

  • Source: Scientific reports [Sci Rep] 2025 Jul 26; Vol. 15 (1), pp. 27294. Date of Electronic Publication: 2025 Jul 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Caerin 1.1 and 1.9 peptides induce acute caspase 3/GSDME-mediated pyroptosis in epithelial cancer cells.

  • Authors : Luo Y; Medical College of Guizhou University, Guiyang, 550025, Guizhou, China.; Li J

Subjects: Pyroptosis*/Pyroptosis*/Pyroptosis*/drug effects ; Caspase 3*/Caspase 3*/Caspase 3*/metabolism ; Peptides*/Peptides*/Peptides*/pharmacology

  • Source: Scientific reports [Sci Rep] 2025 Apr 18; Vol. 15 (1), pp. 13377. Date of Electronic Publication: 2025 Apr 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Memantine abrogates testicular dysfunction induced by risperidone in rats with a potential role of ERK1/2-Nrf2-caspase-3 signaling pathway.

  • Authors : Mohyeldin RH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Deraya University, Minia, 61111, Egypt.; Sharata EE

Subjects: Risperidone*/Risperidone*/Risperidone*/adverse effects ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; Caspase 3*/Caspase 3*/Caspase 3*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Apr 15; Vol. 15 (1), pp. 12914. Date of Electronic Publication: 2025 Apr 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploring cell death mechanisms in spheroid cultures using a novel application of the RIP3-caspase3-assay.

  • Authors : Philippi CI; Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Hagens J

Subjects: Receptor-Interacting Protein Serine-Threonine Kinases*/Receptor-Interacting Protein Serine-Threonine Kinases*/Receptor-Interacting Protein Serine-Threonine Kinases*/metabolism ; Spheroids, Cellular*/Spheroids, Cellular*/Spheroids, Cellular*/metabolism ; Spheroids, Cellular*/Spheroids, Cellular*/Spheroids, Cellular*/drug effects

  • Source: Scientific reports [Sci Rep] 2024 Jul 11; Vol. 14 (1), pp. 16032. Date of Electronic Publication: 2024 Jul 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

PPARγ regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.

  • Authors : Yuan H; Graduate School of Bengbu Medical College, Bengbu, China.; Department of Orthopedics, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China.

Subjects: Apoptosis* ; Caspase 3*/Caspase 3*/Caspase 3*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 May 16; Vol. 14 (1), pp. 11237. Date of Electronic Publication: 2024 May 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The new preservative-free ophthalmic formulation of bilastine 0.6% preserves the ocular surface epithelial integrity in a comparative in vitro study.

  • Authors : Arana E; Research, Development and Innovation Department (R&D+I Department), Faes Farma, Av. Autonomía 10, 48940, Leioa, Bizkaia, Spain.; Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country, Leioa, Spain.

Subjects: Ophthalmic Solutions*/Ophthalmic Solutions*/Ophthalmic Solutions*/pharmacology ; Preservatives, Pharmaceutical*/Preservatives, Pharmaceutical*/Preservatives, Pharmaceutical*/pharmacology ; Cell Survival*/Cell Survival*/Cell Survival*/drug effects

  • Source: Scientific reports [Sci Rep] 2024 Apr 26; Vol. 14 (1), pp. 9598. Date of Electronic Publication: 2024 Apr 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation.

  • Authors : Abdel-Aziz N; Radiation Biology Research Department, National Center for Radiation Research & Technology, Egyptian Atomic Energy Authority, P.O. Box 29, Nasr City, Cairo, Egypt. .; Algeda FR

Subjects: Cytidine Diphosphate Choline*/Cytidine Diphosphate Choline*/Cytidine Diphosphate Choline*/pharmacology ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jul 15; Vol. 15 (1), pp. 25658. Date of Electronic Publication: 2025 Jul 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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