نتائج البحث

E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence.

• Authors : Avenhaus A; German Cancer Research Center (DKFZ), Molecular Therapy of Virus-Associated Cancers, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/physiology ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics

• Source: PLoS pathogens [PLoS Pathog] 2025 Feb 07; Vol. 21 (2), pp. e1012914. Date of Electronic Publication: 2025 Feb 07 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure.

• Authors : Li H; Beijing Institute of Biotechnology, Beijing, China.; College of Basic Medical Sciences, School of Medicine, Zhejiang University, Hangzhou, China.

Subjects: Heart Failure*/Heart Failure*/Heart Failure*/metabolism ; Heart Failure*/Heart Failure*/Heart Failure*/virology ; SARS-CoV-2*

• Source: PLoS pathogens [PLoS Pathog] 2024 Aug 05; Vol. 20 (8), pp. e1012291. Date of Electronic Publication: 2024 Aug 05 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.

• Authors : Zhi H; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Yang L

Subjects: Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/*physiology ; Cellular Senescence/Cellular Senescence/Cellular Senescence/*genetics ; Gene Products, tax/Gene Products, tax/Gene Products, tax/*physiology

• Source: PLoS pathogens [PLoS Pathog] 2011 Apr; Vol. 7 (4), pp. e1002025. Date of Electronic Publication: 2011 Apr 28.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ.

• Authors : Akkouche A; Department of Internal Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.; Department of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Beirut, Lebanon.

Subjects: Cellular Senescence* ; Gene Expression Regulation, Viral*; Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/Basic-Leucine Zipper Transcription Factors/*metabolism

• Source: PLoS pathogens [PLoS Pathog] 2021 Jan 20; Vol. 17 (1), pp. e1009219. Date of Electronic Publication: 2021 Jan 20 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells.

• Authors : DiMaio TA; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.; Vogt DT

Subjects: Cellular Senescence*; Cyclins/Cyclins/Cyclins/*metabolism ; Endothelial Cells/Endothelial Cells/Endothelial Cells/*metabolism

• Source: PLoS pathogens [PLoS Pathog] 2020 Jun 18; Vol. 16 (6), pp. e1008634. Date of Electronic Publication: 2020 Jun 18 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia

• Authors : Schnell, Gretja; Spudich, Serena; Harrington, Patrick

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Immunology

• Source: PLOS Pathogens. 5(4)

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Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype.

• Authors : Trapp-Fragnet L; INRAE, UMR1282 ISP, Equipe Biologie des Virus Aviaires, Nouzilly, France.; Schermuly J

Subjects: Marek Disease*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*virology; Animals

• Source: PLoS pathogens [PLoS Pathog] 2021 Oct 21; Vol. 17 (10), pp. e1010006. Date of Electronic Publication: 2021 Oct 21 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Microglia and macrophages alterations in the CNS during acute SIV infection: A single-cell analysis in rhesus macaques.

• Authors : Xu, Xiaoke¹ (AUTHOR); Niu, Meng¹ (AUTHOR); Lamberty, Benjamin G.¹ (AUTHOR)

• Source: PLoS Pathogens. 9/16/2024, Vol. 20 Issue 9, p1-33. 33p.

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Pseudomonas aeruginosa Transmigrates at Epithelial Cell-Cell Junctions, Exploiting Sites of Cell Division and Senescent Cell Extrusion.

• Authors : Golovkine G; University Grenoble Alpes, Grenoble, France.; CNRS, ERL5261, Grenoble, France.

Subjects: Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*virology ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*pathogenicity

• Source: PLoS pathogens [PLoS Pathog] 2016 Jan 04; Vol. 12 (1), pp. e1005377. Date of Electronic Publication: 2016 Jan 04 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells.

• Authors : Honegger A; Molecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Schilling D

Subjects: DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*biosynthesis ; Oncogene Proteins, Viral/Oncogene Proteins, Viral/Oncogene Proteins, Viral/*metabolism

• Source: PLoS pathogens [PLoS Pathog] 2015 Mar 11; Vol. 11 (3), pp. e1004712. Date of Electronic Publication: 2015 Mar 11 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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