نتائج البحث

CCDC137 knockdown suppresses bladder cancer progression by downregulating SCD.

• Authors : Zhang H; Shantou University Medical College, Shantou, 515000, China.; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518000, China.

Subjects: Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/pathology ; Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/genetics ; Gene Knockdown Techniques*

• Source: Journal of translational medicine [J Transl Med] 2025 Sep 24; Vol. 23 (1), pp. 1013. Date of Electronic Publication: 2025 Sep 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression.

• Authors : Dai C; Abbisko Therapeutics Co., Ltd, Shanghai, 201203, China.; Shen B

Subjects: Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/pathology ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/drug therapy ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2025 Aug 12; Vol. 23 (1), pp. 900. Date of Electronic Publication: 2025 Aug 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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The CTSZ-TRA2A-IL32 axis defines a targetable macrophage-dependent pathway in metastatic prostate cancer.

• Authors : Chen S; Department of Urology, Southwest Hospital, Army Medical University (Third Military Medical University), GaoTanYan Main Street 30, Chongqing, 400038, China.; Deng B

Subjects: Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/pathology ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/genetics ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2025 Aug 05; Vol. 23 (1), pp. 865. Date of Electronic Publication: 2025 Aug 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Meta-analysis of microarray data to identify potential signature genes and MiRNAs associated with the pathogenesis of asthma.

• Authors : Vafadar A; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.

• Source: Journal of translational medicine [J Transl Med] 2025 Jul 15; Vol. 23 (1), pp. 796. Date of Electronic Publication: 2025 Jul 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.

• Authors : Liu L; School of Basic Medical Sciences, The Second Affiliated Hospital of Shandong First Medical University & Shandong Academy of Medical Science, Taian, 271000, China.; Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Clinical & Basic Medical College, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/blood

• Source: Journal of translational medicine [J Transl Med] 2025 Jul 11; Vol. 23 (1), pp. 781. Date of Electronic Publication: 2025 Jul 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Expression signatures with specificity for type I and II IFN response and relevance for autoimmune diseases and cancer.

• Authors : Aybey B; Clinical Measurement Sciences, Merck Healthcare KGaA, Oncology Data Science, Darmstadt, Germany. .; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany. .

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Interferon Type I*/Interferon Type I*/Interferon Type I*/genetics ; Interferon Type I*/Interferon Type I*/Interferon Type I*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2025 Jul 03; Vol. 23 (1), pp. 740. Date of Electronic Publication: 2025 Jul 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Spatial transcriptomics and multi-omics reveal relapse and resistance mechanisms of EndMT-derived CAFs mediated by TNC and FLNC in glioblastoma.

• Authors : Ji L; Center of Clinical Research, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, 214023, China.; Department of Laboratory Medicine, Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, 214023, China.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics

• Source: Journal of translational medicine [J Transl Med] 2025 Jul 01; Vol. 23 (1), pp. 702. Date of Electronic Publication: 2025 Jul 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Plasma exosomal tsRNA may be used as a marker for differential diagnosis of benign and malignant pulmonary nodules.

• Authors : Zhou N; Shandong University Cancer Center, No. 440, Jiyan Road, Huaiyin District, Jinan, Shandong, 250017, China.; Blood Center of Shandong Province, Blood Group Reference Laboratory, No.22, Shanshi East Road, Lixia District, Jinan, Shandong, 250000, China.

Subjects: Exosomes*/Exosomes*/Exosomes*/metabolism ; Exosomes*/Exosomes*/Exosomes*/ultrastructure ; Biomarkers, Tumor*/Biomarkers, Tumor*/Biomarkers, Tumor*/blood

• Source: Journal of translational medicine [J Transl Med] 2025 Jul 01; Vol. 23 (1), pp. 712. Date of Electronic Publication: 2025 Jul 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients

• Authors : Ao Wang; Xiao-Fei Zhang; Cong-Jian Luo

Subjects: Polycystic ovary syndrome; Granulosa cells; Lysine acetyltransferase 2B

• Source: Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-17 (2025)

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Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer.

• Authors : Han YB; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/immunology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology

• Source: Journal of translational medicine [J Transl Med] 2025 May 23; Vol. 23 (1), pp. 576. Date of Electronic Publication: 2025 May 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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