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Academic Journal

Initiation of the alternative pathway of complement and the history of "tickover".

  • Authors : Pangburn MK; Center for Biomedical Research, University of Texas Health Science Center, Tyler, Texas, USA.

Subjects: Complement C3*/Complement C3*/Complement C3*/metabolism ; Complement C3b*/Complement C3b*/Complement C3b*/metabolism; Humans

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 64-70. Date of Electronic Publication: 2022 Sep 11.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

Low-molecular weight inhibitors of the alternative complement pathway.

  • Authors : Schubart A; Novartis Institutes for BioMedical Research, Basel, Switzerland.; Flohr S

Subjects: Complement Pathway, Alternative* ; Atypical Hemolytic Uremic Syndrome*/Atypical Hemolytic Uremic Syndrome*/Atypical Hemolytic Uremic Syndrome*/metabolism; Humans

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 339-357. Date of Electronic Publication: 2022 Oct 11.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

The Factor H protein family: The switchers of the complement alternative pathway.

  • Authors : Lucientes-Continente L; Department of Immunology, Ophthalmology and ENT, School of Medicine, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.; Márquez-Tirado B

Subjects: Complement Factor H*/Complement Factor H*/Complement Factor H*/metabolism ; Complement System Proteins*/Complement System Proteins*/Complement System Proteins*/metabolism; Humans

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 25-45. Date of Electronic Publication: 2022 Nov 16.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

C3-dependent effector functions of complement.

  • Authors : Zarantonello A; Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France.; Revel M

Subjects: Complement C3*/Complement C3*/Complement C3*/analysis ; Complement C3*/Complement C3*/Complement C3*/metabolism ; Complement C3b*/Complement C3b*/Complement C3b*/metabolism

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 120-138. Date of Electronic Publication: 2022 Oct 22.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway.

Subjects: Complement System Proteins*/Complement System Proteins*/Complement System Proteins*/genetics ; Complement System Proteins*/Complement System Proteins*/Complement System Proteins*/metabolism ; Hemoglobinuria, Paroxysmal*/Hemoglobinuria, Paroxysmal*/Hemoglobinuria, Paroxysmal*/drug therapy

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 402-419. Date of Electronic Publication: 2022 Nov 12.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

Genetic variability shapes the alternative pathway complement activity and predisposition to complement-related diseases.

  • Authors : Rodríguez de Córdoba S; Centro de Investigaciones Biológicas Margarita Salas and Ciber de Enfermedades Raras, Madrid, Spain.

Subjects: Genetic Predisposition to Disease* ; Complement System Proteins*/Complement System Proteins*/Complement System Proteins*/genetics; Humans

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 71-90. Date of Electronic Publication: 2022 Sep 11.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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Academic Journal

The complement alternative pathway in health and disease-activation or amplification?

Subjects: Complement Activation* ; Complement Pathway, Alternative*; Humans

  • Source: Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 6-14. Date of Electronic Publication: 2022 Nov 24.Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X

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