نتائج البحث

Integration of ATAC-Seq and RNA-Seq reveals FOSL2 drives human liver progenitor-like cell aging by regulating inflammatory factors.

• Authors : Ding M; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.; Department of Interventional Oncology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/genetics ; Chromatin*/Chromatin*/Chromatin*/genetics ; Chromatin Immunoprecipitation Sequencing*

• Source: BMC genomics [BMC Genomics] 2023 May 13; Vol. 24 (1), pp. 260. Date of Electronic Publication: 2023 May 13.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Modelling the onset of senescence at the G1/S cell cycle checkpoint.

• Authors : Mombach JC; Bugs CA; Chaouiya C

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/genetics ; DNA Damage* ; G1 Phase Cell Cycle Checkpoints*/G1 Phase Cell Cycle Checkpoints*/G1 Phase Cell Cycle Checkpoints*/genetics

• Source: BMC genomics [BMC Genomics] 2014; Vol. 15 Suppl 7, pp. S7. Date of Electronic Publication: 2014 Oct 27.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma.

• Authors : Lafferty-Whyte K; Centre for Oncology and Applied Pharmacology, University of Glasgow, Cancer Research UK Beatson Laboratories, Garscube Estate, Switchback Road, Bearsden, Glasgow G611BD, UK.; Bilsland A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Cellular Senescence/Cellular Senescence/Cellular Senescence/*genetics ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*drug effects

• Source: BMC genomics [BMC Genomics] 2010 Oct 01; Vol. 11, pp. 532. Date of Electronic Publication: 2010 Oct 01.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence.

• Authors : Ohori M; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan. .; Nakayama Y

Subjects: Alternative Splicing* ; Gene Regulatory Networks*; Cellular Senescence/Cellular Senescence/Cellular Senescence/genetics

• Source: BMC genomics [BMC Genomics] 2021 Dec 02; Vol. 22 (1), pp. 869. Date of Electronic Publication: 2021 Dec 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Identification and functional analysis of circular RNAs during mitochondrial damage induced by infectious bovine rhinotracheitis virus infection in Madin–Darby bovine kidney cells.

• Authors : Ma, Yingcai^1,2 (AUTHOR) ; Liu, Jiaxin^1,2 (AUTHOR) ; Xu, Lianping³ (AUTHOR)

• Source: BMC Genomics. 10/24/2025, Vol. 26 Issue 1, p1-19. 19p.

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A cmap-enabled gene expression signature-matching approach identifies small-molecule inducers of accelerated cell senescence.

• Authors : Wu D; Department of Molecular Genetics and Cell Biology and Ludwig Center for Metastasis Research, The University of Chicago, 929 East 57th Street, GCIS W522A, Chicago, IL, 60637, USA.; Pepowski B

Subjects: Cellular Senescence/Cellular Senescence/Cellular Senescence/*drug effects ; Cellular Senescence/Cellular Senescence/Cellular Senescence/*genetics ; Computational Biology/Computational Biology/Computational Biology/*methods

• Source: BMC genomics [BMC Genomics] 2019 Apr 15; Vol. 20 (1), pp. 290. Date of Electronic Publication: 2019 Apr 15.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia

• Authors : Hannah Voic; Xiuying Li; Jun-Ho Jang

Subjects: 0301 basic medicine; 0303 health sciences; Cell Survival

• Source: BMC GenomicsBMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)

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Analysis of two mechanisms of telomere maintenance based on the theory of g-Networks and stochastic automata networks.

• Authors : Lee KH; Department of Statistics, Rice University, 6100 Main Street, Houston, 77057, TX, USA.; Kimmel M

Subjects: Telomerase*/Telomerase*/Telomerase*/genetics ; Telomere*/Telomere*/Telomere*/genetics; Cell Division

• Source: BMC genomics [BMC Genomics] 2020 Sep 09; Vol. 21 (Suppl 9), pp. 587. Date of Electronic Publication: 2020 Sep 09.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

• Authors : Vassilis G. Gorgoulis; Dafni-Eleftheria Pefani; Thorbjørn Krejsgaard

Subjects: 0301 basic medicine; Carcinogenesis; rDNA

• Source: BMC GenomicsBMC Genomics, Vol 19, Iss 1, Pp 1-22 (2018)Komseli, E S, Pateras, I S, Krejsgaard, T, Stawiski, K, Rizou, S V,

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A modular analysis of microglia gene expression, insights into the aged phenotype.

• Authors : Cho CE; Ionis Pharmaceuticals, Inc, Carlsbad, CA, 92010, USA. .; Damle SS

Subjects: Transcriptome*/Transcriptome*/Transcriptome*/drug effects; Cellular Senescence/Cellular Senescence/Cellular Senescence/*genetics ; Microglia/Microglia/Microglia/*metabolism

• Source: BMC genomics [BMC Genomics] 2019 Feb 28; Vol. 20 (1), pp. 164. Date of Electronic Publication: 2019 Feb 28.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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