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  • 1-10 ل  8,693 نتائج ل ""proteolysis""

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Academic Journal

Discovery of a Proteolysis Targeting Chimera for TRKA and RET-derived oncoproteins.

  • Authors : Moccia M; Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia 'G. Salvatore' (IEOMI) del CNR, Naples, Italia.; Zhang L

Subjects: Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/metabolism ; Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/antagonists & inhibitors ; Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/Proto-Oncogene Proteins c-ret*/genetics

  • Source: Scientific reports [Sci Rep] 2025 Nov 25; Vol. 15 (1), pp. 41770. Date of Electronic Publication: 2025 Nov 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design and Synthesis of Novel Candidate CK1δ Proteolysis Targeting Chimeras (PROTACs).

  • Authors : Arnold M; Institute of Pharmacy, Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany.; Thompson T

Subjects: Proteolysis*/Proteolysis*/Proteolysis*/drug effects ; Casein Kinase Idelta*/Casein Kinase Idelta*/Casein Kinase Idelta*/antagonists & inhibitors ; Casein Kinase Idelta*/Casein Kinase Idelta*/Casein Kinase Idelta*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2025 Nov 18; Vol. 30 (22). Date of Electronic Publication: 2025 Nov 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Targeting Protein Tyrosine Phosphatases via PROteolysis-TArgeting Chimeras (PROTACs): Current Developments and Prospects.

  • Authors : Maccari R; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.

Subjects: Proteolysis*/Proteolysis*/Proteolysis*/drug effects ; Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/antagonists & inhibitors ; Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2025 Nov 18; Vol. 30 (22). Date of Electronic Publication: 2025 Nov 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Regulated proteolysis of green fluorescent protein fusion proteins in Aspergillus fumigatus.

  • Authors : Paul S; Department of Molecular Physiology and Biophysics, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, United States.; Moye-Rowley WS

Subjects: Aspergillus fumigatus*/Aspergillus fumigatus*/Aspergillus fumigatus*/genetics ; Aspergillus fumigatus*/Aspergillus fumigatus*/Aspergillus fumigatus*/metabolism ; Green Fluorescent Proteins*/Green Fluorescent Proteins*/Green Fluorescent Proteins*/metabolism

  • Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2026 Feb 04; Vol. 16 (2).Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera.

  • Authors : Sin YY; School of Cardiovascular and Metabolic Health, University of Glasgow, UK.; Giblin A

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/genetics ; Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/Cyclic Nucleotide Phosphodiesterases, Type 4*/chemistry

  • Source: The FEBS journal [FEBS J] 2025 Jul; Vol. 292 (13), pp. 3360-3377. Date of Electronic Publication: 2024 Dec 13.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Sodium Benzoate and Potassium Sorbate Inhibit Proteolysis and Promote Lipid Oxidation in Atlantic Herring Marinades Produced on an Industrial Scale.

  • Authors : Szymczak M; Department of Toxicology, Dairy Technology and Food Storage, Faculty of Food Sciences and Fisheries, West Pomeranian University of Technology in Szczecin, Pawła VI Street No. 3, 71-459 Szczecin, Poland.; Kamiński P

Subjects: Sodium Benzoate*/Sodium Benzoate*/Sodium Benzoate*/pharmacology ; Sodium Benzoate*/Sodium Benzoate*/Sodium Benzoate*/chemistry ; Sorbic Acid*/Sorbic Acid*/Sorbic Acid*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2025 Oct 15; Vol. 30 (20). Date of Electronic Publication: 2025 Oct 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Rapid and high-throughput screening of proteolysis targeting chimeras using a dual-reporter system expressing fluorescence protein and luciferase.

  • Authors : Meng S; Department of Pharmacy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin'S Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.; Meng Y

Subjects: Proteolysis*/Proteolysis*/Proteolysis*/drug effects ; High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods ; Green Fluorescent Proteins*/Green Fluorescent Proteins*/Green Fluorescent Proteins*/metabolism

  • Source: BMC biology [BMC Biol] 2025 Feb 21; Vol. 23 (1), pp. 51. Date of Electronic Publication: 2025 Feb 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Limited Proteolysis as a Regulator of Lymphatic Vessel Function and Architecture.

  • Authors : Miyazaki T; Department of Biochemistry, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.

Subjects: Lymphatic Vessels*/Lymphatic Vessels*/Lymphatic Vessels*/metabolism ; Lymphatic Vessels*/Lymphatic Vessels*/Lymphatic Vessels*/physiology ; Lymphatic Vessels*/Lymphatic Vessels*/Lymphatic Vessels*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 24; Vol. 26 (15). Date of Electronic Publication: 2025 Jul 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Effect of dry ice addition and wilting on the rates of fermentation and proteolysis in ensiled alfalfa.

  • Authors : Borsuk-Stanulewicz M; Department of Animal Nutrition, Feed Science and Cattle Breeding, Faculty of Animal Bioengineering, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719, Olsztyn, Poland. .; Białobrzewski I

Subjects: Medicago sativa*/Medicago sativa*/Medicago sativa*/metabolism ; Medicago sativa*/Medicago sativa*/Medicago sativa*/chemistry ; Silage*/Silage*/Silage*/analysis

  • Source: Scientific reports [Sci Rep] 2025 Jul 02; Vol. 15 (1), pp. 23375. Date of Electronic Publication: 2025 Jul 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

HSP70 Interactome-Mediated Proteolysis Targeting Chimera (HSP70-PROTAC) for Ferroptosis-Driven Cancer Treatment.

  • Authors : Dong J; Center for Innovative Drug Research, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China.; Li Y

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; HSP70 Heat-Shock Proteins*/HSP70 Heat-Shock Proteins*/HSP70 Heat-Shock Proteins*/metabolism ; HSP70 Heat-Shock Proteins*/HSP70 Heat-Shock Proteins*/HSP70 Heat-Shock Proteins*/genetics

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Feb; Vol. 13 (12), pp. e13655. Date of Electronic Publication: 2025 Dec 12.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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  • 1-10 ل  8,693 نتائج ل ""proteolysis""