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Crotamine/siRNA Nanocomplexes for Functional Downregulation of Syndecan-1 in Renal Proximal Tubular Epithelial Cells.

• Authors : Campeiro JD; Department Nephrology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, De Brug, 4th Floor, AA53, 9713 GZ Groningen, The Netherlands.; Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Rua 3 de Maio 100, Ed. INFAR, 3rd Floor, São Paulo 04044-020, Brazil.

• Source: Pharmaceutics [Pharmaceutics] 2023 May 23; Vol. 15 (6). Date of Electronic Publication: 2023 May 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print)

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Effect of the snake venom component crotamine on lymphatic endothelial cell responses and lymph transport.

• Authors : Si H; Department of Medical Physiology, Texas A&M University Health Science Center, Bryan, Texas, USA.; Yin C

Subjects: Snake Bites*; Humans ; Endothelial Cells

• Source: Microcirculation (New York, N.Y. : 1994) [Microcirculation] 2023 Apr; Vol. 30 (2-3), pp. e12775. Date of Electronic Publication: 2022 Jun 24.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9434935 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Antinociceptive and Anti-Inflammatory Effects of Recombinant Crotamine in Mouse Models of Pain.

• Authors : Park JY; Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.; Do BH

Subjects: Analgesics/Analgesics/Analgesics/*pharmacology ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*pharmacology

• Source: Toxins [Toxins (Basel)] 2021 Oct 06; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Effects of the Natural Peptide Crotamine from a South American Rattlesnake on Candida auris , an Emergent Multidrug Antifungal Resistant Human Pathogen.

• Authors : Dal Mas C; Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo SP 04038-032, Brazil. .; Rossato L

Subjects: Crotalus*; Candida/Candida/Candida/*drug effects ; Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*pharmacology

• Source: Biomolecules [Biomolecules] 2019 May 28; Vol. 9 (6). Date of Electronic Publication: 2019 May 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Intradermal Application of Crotamine Induces Inflammatory and Immunological Changes In Vivo.

• Authors : Silvestrini AVP; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Av. do Café, s/n, CEP 14040-903 Ribeirão Preto, SP, Brazil. .; de Macedo LH

Subjects: Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*toxicity ; Inflammation/Inflammation/Inflammation/*chemically induced; Animals

• Source: Toxins [Toxins (Basel)] 2019 Jan 14; Vol. 11 (1). Date of Electronic Publication: 2019 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Long term safety of targeted internalization of cell penetrating peptide crotamine into renal proximal tubular epithelial cells in vivo.

• Authors : Campeiro JD; Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.; Dam W

Subjects: Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/adverse effects ; Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/pharmacokinetics ; Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/Cell-Penetrating Peptides*/pharmacology

• Source: Scientific reports [Sci Rep] 2019 Mar 01; Vol. 9 (1), pp. 3312. Date of Electronic Publication: 2019 Mar 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles.

• Authors : Lima SC; Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.; Porta LC

Subjects: Hindlimb* ; Paralysis*; Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*pharmacology

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Aug 06; Vol. 12 (8), pp. e0006700. Date of Electronic Publication: 2018 Aug 06 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Co-Localization of Crotamine with Internal Membranes and Accentuated Accumulation in Tumor Cells.

• Authors : Mambelli-Lisboa NC; Laboratory of Genetics, Butantan Institute, Sao Paulo 05503-900, Brazil. .; CENTD-Center of Excellence in New Target Discovery, Butantan Institute, Sao Paulo 05503-900, Brazil. .

Subjects: Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*metabolism ; Intracellular Membranes/Intracellular Membranes/Intracellular Membranes/*metabolism; Animals

• Source: Molecules (Basel, Switzerland) [Molecules] 2018 Apr 20; Vol. 23 (4). Date of Electronic Publication: 2018 Apr 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Crotamine-like from Southern Pacific rattlesnake (Crotalus oreganus helleri) Venom acts on human leukemia (K-562) cell lines and produces ultrastructural changes on mice adrenal gland.

• Authors : Sánchez EE; a National Natural Toxins Research Center (NNTRC) , Texas A&M University-Kingsville , Kingsville , TX , USA.; d Department of Chemistry , Texas A&M University-Kingsville , Kingsville , TX , USA.

Subjects: Adrenal Glands/Adrenal Glands/Adrenal Glands/*drug effects ; Adrenal Glands/Adrenal Glands/Adrenal Glands/*ultrastructure ; Crotalid Venoms/Crotalid Venoms/Crotalid Venoms/*toxicity

• Source: Ultrastructural pathology [Ultrastruct Pathol] 2018 Mar-Apr; Vol. 42 (2), pp. 116-123.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8002867 Publication Model: Print Cited Medium: Internet ISSN: 1521-0758

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Crotamine induces browning of adipose tissue and increases energy expenditure in mice.

• Authors : Marinovic MP; Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.; Campeiro JD

Subjects: Adipose Tissue, Brown/Adipose Tissue, Brown/Adipose Tissue, Brown/*drug effects ; Adipose Tissue, White/Adipose Tissue, White/Adipose Tissue, White/*drug effects ; Body Weight/Body Weight/Body Weight/*drug effects

• Source: Scientific reports [Sci Rep] 2018 Mar 22; Vol. 8 (1), pp. 5057. Date of Electronic Publication: 2018 Mar 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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