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Academic Journal

Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents.

Authors : Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.; Hamdi A

Subjects: Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology ; Antipyrine*/Antipyrine*/Antipyrine*/pharmacology; Humans

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2162511.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny.

Authors : Alshaye NA; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.; Elgohary MK

Subjects: Cyclooxygenase 2 Inhibitors* ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/therapeutic use; Humans

Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 15; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Design, Synthesis and Evaluation of Antioxidant and NSAID Derivatives with Antioxidant, Anti-Inflammatory and Plasma Lipid Lowering Effects.

Authors : Theodosis-Nobelos P; Department of Pharmacy, School of Health Sciences, Frederick University, Nicosia 1036, Cyprus.; Marc G

Subjects: Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/chemistry ; Antioxidants*/Antioxidants*/Antioxidants*/chemistry; Rats

Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 26; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents.

Authors : Kamboj P; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.; Anjali

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Cardiomyopathies* ; Chemical and Drug Induced Liver Injury*

Source: Scientific reports [Sci Rep] 2024 Apr 11; Vol. 14 (1), pp. 8457. Date of Electronic Publication: 2024 Apr 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel Flurbiprofen Derivatives as Antioxidant and Anti-Inflammatory Agents: Synthesis, In Silico, and In Vitro Biological Evaluation.

Authors : Ivanov I; Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 'Tsar Assen' Street., 4000 Plovdiv, Bulgaria.; Manolov S

Subjects: Flurbiprofen*/Flurbiprofen*/Flurbiprofen*/pharmacology; Humans ; Antioxidants/Antioxidants/Antioxidants/pharmacology

Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 12; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents.

Authors : Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.; Ioele G

Subjects: Cytochrome P-450 CYP1A2* ; Prodrugs*/Prodrugs*/Prodrugs*/pharmacology; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 28; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Design, biological evaluation, and molecular modelling insights of cupressic acid derivatives as promising anti-inflammatory agents.

Authors : Soliman AF; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Elimam DM

Subjects: Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/pharmacology ; Interleukin-6*; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/metabolism

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2187327.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.

Authors : Badawi WA; Department of Pharmaceutical Chemistry, Damanhour University, Damanhour, Buhaira, Egypt.; Rashed M

Subjects: Carbonic Anhydrases*/Carbonic Anhydrases*/Carbonic Anhydrases*/metabolism; Molecular Structure ; Structure-Activity Relationship

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2201407.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Discovery of New Heterocyclic/Benzofuran Hybrids as Potential Anti-Inflammatory Agents: Design, Synthesis, and Evaluation of the Inhibitory Activity of Their Related Inflammatory Factors Based on NF-κB and MAPK Signaling Pathways.

Authors : Chen Y; College of pharmacy, Guangxi University of Chinese Medicine, Nanning 530222, China.; Chen R

Subjects: Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/chemistry ; Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology ; Benzofurans*/Benzofurans*/Benzofurans*/chemistry

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 10; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In Vitro and In Silico Activities of E . radiata and E . cinerea as an Enhancer of Antibacterial, Antioxidant, and Anti-Inflammatory Agents.

Authors : Elkolli H; Laboratory of Multiphasic Polymeric Materials, Départment of Process Engineering, Faculty of Technology, University Ferhat Abbas of Setif 1, Setif 19000, Algeria.; Elkolli M

Subjects: Antioxidants*/Antioxidants*/Antioxidants*/pharmacology ; Antioxidants*/Antioxidants*/Antioxidants*/chemistry ; Plant Extracts*/Plant Extracts*/Plant Extracts*/pharmacology

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 18; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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نتائج البحث

فلترة النتائج

Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents.

Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny.

Design, Synthesis and Evaluation of Antioxidant and NSAID Derivatives with Antioxidant, Anti-Inflammatory and Plasma Lipid Lowering Effects.

Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents.

Novel Flurbiprofen Derivatives as Antioxidant and Anti-Inflammatory Agents: Synthesis, In Silico, and In Vitro Biological Evaluation.

Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents.

Design, biological evaluation, and molecular modelling insights of cupressic acid derivatives as promising anti-inflammatory agents.

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.

Discovery of New Heterocyclic/Benzofuran Hybrids as Potential Anti-Inflammatory Agents: Design, Synthesis, and Evaluation of the Inhibitory Activity of Their Related Inflammatory Factors Based on NF-κB and MAPK Signaling Pathways.

In Vitro and In Silico Activities of E . radiata and E . cinerea as an Enhancer of Antibacterial, Antioxidant, and Anti-Inflammatory Agents.