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Pharmacokinetic Modelling of Levosimendan in Adults (MILADECMO)

• Authors : University Hospital, Lille; Amiens University Hospital, France

• Source: Pharmacokinetic Modelling of Levosimendan in Adults in Cardiogenic Shock With or Without Extracorporeal Membrane Oxygenation Support

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Pharmacokinetics of Once Daily Darunavir/Ritonavir in HIV-infected Children (DAPHNE)

• Authors : Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); UMC Utrecht

• Source: Once Daily Darunavir/Ritonavir in HIV-infected Children 6-12 Years Old: a Pharmacokinetic Validation of Model Based Dosing RecommendationsBastiaans DET, Geelen

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Pharmacokinetic Profile of Lidocaine Given as a Weight-based Infusion for Postoperative Surgical Pain Control

• Source: Pharmacokinetic Profile of Lidocaine Given as a Weight-based Infusion for Postoperative Surgical Pain Control

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Evaluation of the Use of the FUR to Quantify Tumor Glucose Consumption in Oncologic PET

• Authors : Roel Wierts, Medical physicist

• Source: Evaluation of the Fractional Uptake Rate (FUR) in 18F-FDG PET/CT to Assess Tumour Metabolic Activity

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Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease (SHUFFLE)

• Source: Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease: Evaluation of Exposure Parameters

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Tuberculosis Drug Levels and Continuous Glucose Monitoring in Diabetic Patients

• Source: Tuberculosis Drug Levels and Continuous Glucose Monitoring in Diabetic Patients

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Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

• Source: A Randomized, Four-arm Open Label Phase Two-b Clinical Trial to Evaluate the Pharmacokinetics, Safety/Tolerability and Efficacy of High Dose Rifampicin in TB-HIV Co-infected Patients on Efavirenz- or

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The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

• Source: The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal HemoglobinuriaTer Avest M, Langemeijer SMC, van den Heuvel LPWJ, Baas LM, van de Kar NCAJ, Ter Heine

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Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

• Authors : Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); dr. P. Noordzij, Principal Investigator

• Source: Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery - AGE AWARE II

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Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19 (ARCHAIC)

• Authors : ZonMw: The Netherlands Organisation for Health Research and Development; Andy I.M. Hoepelman, Head of Infectious Diseases

• Source: An Open Label Cluster Randomized Controlled Trial of Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19

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