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A Phase 2b Study of Zagociguat in Patients With MELAS (PRIZM)

  • Source: Phase 2b Randomized, Double-blind, Placebo-controlled Crossover Study Evaluating the Efficacy and Safety of Zagociguat in Participants With MELAS (PRIZM)

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A Study to Assess TTI-0102 vs Placebo in MELAS Patients

  • Source: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral TTI-0102 for Treatment of Patients With

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An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

  • Source: An Open-label Extension Study Evaluating the Safety of Zagociguat in Participants With MELAS Who Completed TIS6463-203

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L-Citrulline Dose Finding Safety Study in MELAS

  • Source: Phase-1, Dose Finding and Safety Study on L- Citrulline Treatment of Nitric Oxide Deficiency in MELASEl-Hattab AW, Emrick LT, Hsu JW, Chanprasert S, Almannai M,

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Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

  • Source: A Phase 2a Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Individuals With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (

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Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome

  • Authors : Jesús González de la Aleja Tejera, Jesús González de la Aleja Tejera, MD, PhD, Principal Investigator

  • Source: Clinical Long Term Evaluation of Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome in Order to Prevent

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Effectiveness of Ketogenic Diet in MELAS Syndrome

  • Source: Clinical Trial of Ketogenic Diet in the Treatment of Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-like Episodes(MELAS)

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Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

  • Authors : Jesús González de la Aleja Tejera, Jesús González de la Aleja Tejera, MD, PhD

  • Source: Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome in Order to Prevent Neurological Damage.

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Melatonin in ADHD and Sleep Problems (MELAS)

  • Source: Melatonin - Production and Release in Children and Adolescents With ADHD and Chronic Sleep Problems and Effects of Melatonin on Sleep

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