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Academic Journal

Identification of novel DYRK1A inhibitors as treatment options for alzheimer's disease through comprehensive in silico approaches.

Authors : Makinde, Ibrahim Akindeji¹ (AUTHOR); Hammed, Sheriffdeen Oladimeji^2,3 (AUTHOR); Kumar, Neeraj⁴ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *ENZYME inhibitors; *DRUG efficacy

Source: Scientific Reports. 10/15/2025, Vol. 15 Issue 1, p1-31. 31p.

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Academic Journal

Association between antemortem plasma and structural MRI biomarkers and postmortem tau pathology in the Mayo Clinic Study of Aging.

Authors : Hu, Mingzhao¹ (AUTHOR); Moloney, Christina M.² (AUTHOR); Przybelski, Scott A.¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *TAUOPATHIES; *PREDICTION models

Source: Alzheimer's Research & Therapy. 10/14/2025, Vol. 17 Issue 1, p1-13. 13p.

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Academic Journal

Beyond amyloid: nanobody-mediated neuroinflammatory therapy for Alzheimer's disease.

Authors : Amniouel, Soukaina¹ (AUTHOR); Suh, Jessica¹ (AUTHOR); Zheng, Wei¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *NEUROINFLAMMATION; *AMYLOID beta-protein

Source: Translational Neurodegeneration. 10/13/2025, Vol. 14 Issue 1, p1-25. 25p.

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Academic Journal

Photothermal nano-agents: an innovative trident weapon for accurate and effective treatment of alzheimer's disease.

Authors : Chen, Jianfei¹ (AUTHOR); Zhang, Xiaowei^2,3,4 (AUTHOR); Sun, Jinpan¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *NEAR infrared radiation; *COGNITION

Source: Journal of Nanobiotechnology. 10/10/2025, Vol. 23 Issue 1, p1-29. 29p.

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Academic Journal

Changes in Plasma Aβ42/40 Ratio and p-Tau181 in Amyloid-Positive Patients Treated with Sirolimus.

Authors : Leibowitz, Jonathan S.^1,2 (AUTHOR); Kumi, Frank¹ (AUTHOR); Naseif, Araksy¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *BIOMARKERS; *THERAPEUTICS

Source: Bratislava Medical Journal / Bratislavské Lekárske Listy. Oct2025, Vol. 126 Issue 10, p2432-2436. 5p.

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Academic Journal

Tau-Targeted Therapeutic Strategies: Mechanistic Targets, Clinical Pipelines, and Analysis of Failures.

Authors : Shen, Xinai¹ (AUTHOR); Li, Huan¹ (AUTHOR); Zhang, Beiyu¹ (AUTHOR)

Subjects: *TAU proteins; *ALZHEIMER'S disease; *POST-translational modification

Source: Cells (2073-4409). Oct2025, Vol. 14 Issue 19, p1506. 37p.

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Academic Journal

Evaluation of Neuroprotective Effects of Plant-Derived Alkaloids in Animal Models of Alzheimer’s disease.

Authors : Kriti, Komal¹; Tiwari, Reshu²; Mohapatra, Rashmi³

Subjects: *TUMOR necrosis factors; *TAU proteins; *NEUROFIBRILLARY tangles

Source: Cuestiones de Fisioterapia. 2025, Vol. 54 Issue 4, p6386-6397. 12p.

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Academic Journal

Anti-Amyloid Therapies for Alzheimer's Disease: Progress, Pitfalls, and the Path Ahead.

Authors : Papaliagkas, Vasileios¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *LECANEMAB; *AMYLOIDEUROPEAN Medicines Agency ; UNITED States. Food & Drug Administration

Source: International Journal of Molecular Sciences. Oct2025, Vol. 26 Issue 19, p9529. 9p.

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Academic Journal

The Biomarker Profile of Alzheimer's Disease for Disease-Modifying Treatment Eligibility: Questions and Debates.

Authors : Athanasaki, Athanasia¹ (AUTHOR); Tsantzali, Ioanna^1,2 (AUTHOR); Theodorou, Aikaterini¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *BIOMARKERS; *CLINICAL trials

Source: International Journal of Molecular Sciences. Oct2025, Vol. 26 Issue 19, p9531. 20p.

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Academic Journal

Temporal Interactome Mapping of Human Tau in Drosophila Reveals Progressive Mitochondrial Engagement and Porin/VDAC1-Dependent Modulation of Toxicity.

Authors : Tsakiri, Eleni¹ (AUTHOR); Samiotaki, Martina² (AUTHOR); Skoulakis, Efthimios M. C.¹ (AUTHOR)

Subjects: *MITOCHONDRIA; *PORINS (Proteins); *DROSOPHILA

Source: International Journal of Molecular Sciences. Oct2025, Vol. 26 Issue 19, p9741. 22p.

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نتائج البحث

فلترة النتائج

Identification of novel DYRK1A inhibitors as treatment options for alzheimer's disease through comprehensive in silico approaches.

Association between antemortem plasma and structural MRI biomarkers and postmortem tau pathology in the Mayo Clinic Study of Aging.

Beyond amyloid: nanobody-mediated neuroinflammatory therapy for Alzheimer's disease.

Photothermal nano-agents: an innovative trident weapon for accurate and effective treatment of alzheimer's disease.

Changes in Plasma Aβ42/40 Ratio and p-Tau181 in Amyloid-Positive Patients Treated with Sirolimus.

Tau-Targeted Therapeutic Strategies: Mechanistic Targets, Clinical Pipelines, and Analysis of Failures.

Evaluation of Neuroprotective Effects of Plant-Derived Alkaloids in Animal Models of Alzheimer’s disease.

Anti-Amyloid Therapies for Alzheimer's Disease: Progress, Pitfalls, and the Path Ahead.

The Biomarker Profile of Alzheimer's Disease for Disease-Modifying Treatment Eligibility: Questions and Debates.

Temporal Interactome Mapping of Human Tau in Drosophila Reveals Progressive Mitochondrial Engagement and Porin/VDAC1-Dependent Modulation of Toxicity.

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