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Academic Journal

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

Subjects: A549 cells; cell cycle arrest; Macrophage migration inhibitory factor (MIF)

  • Source: Xiao, Z, Song, S, Chen, D, van Merkerk, R, van der Wouden, P, Cool, R, Quax, W, Poelarends, G, Melgert, B & Dekker, F J 2021, 'Proteolysis Targeting Chimera (PROTAC) for

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Academic Journal

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

Subjects: A549 cells; cell cycle arrest; Macrophage migration inhibitory factor (MIF)

  • Source: Xiao, Z, Song, S, Chen, D, van Merkerk, R, van der Wouden, P, Cool, R, Quax, W, Poelarends, G, Melgert, B & Dekker, F J 2021, 'Proteolysis Targeting Chimera (PROTAC) for

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Academic Journal

Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy

  • Source: Zhang, H, Zhang, Y, Feng, Z, Shuai, M, Ma, X, Wang, S, Yu, S, Deng, R, Luo, D, Shi, J, Pu, C & Li, R 2024, 'Discovery of Novel Proteolysis-Targeting Chimera Molecules as

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Academic Journal

Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy

  • Source: Zhang, H, Zhang, Y, Feng, Z, Shuai, M, Ma, X, Wang, S, Yu, S, Deng, R, Luo, D, Shi, J, Pu, C & Li, R 2024, 'Discovery of Novel Proteolysis-Targeting Chimera Molecules as

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Academic Journal

Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras

  • Source: Zhao, C & Dekker, F J 2022, 'Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras', ACS Pharmacology & Translational Science, vol. 5, no.

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Academic Journal

Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras

  • Source: Zhao, C & Dekker, F J 2022, 'Novel Design Strategies to Enhance the Efficiency of Proteolysis Targeting Chimeras', ACS Pharmacology & Translational Science, vol. 5, no.

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Academic Journal

The tale of proteolysis targeting chimeras (PROTACs) for leucine-rich repeat kinase 2 (LRRK2)

Subjects: LRRK2; Cereblon; PROTAC

  • Source: Konstantinidou, M, Oun, A, Pathak, P, Zhang, B, Wang, Z, ter Brake, F, Dolga, A, Kortholt, A & Doemling, A 2021, 'The tale of proteolysis targeting chimeras (PROTACs)

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Academic Journal

The tale of proteolysis targeting chimeras (PROTACs) for leucine-rich repeat kinase 2 (LRRK2)

Subjects: LRRK2; Cereblon; PROTAC

  • Source: Konstantinidou, M, Oun, A, Pathak, P, Zhang, B, Wang, Z, ter Brake, F, Dolga, A, Kortholt, A & Doemling, A 2021, 'The tale of proteolysis targeting chimeras (PROTACs)

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Academic Journal

EpCAM proteolysis:new fragments with distinct functions?

Subjects: cell-cell contact; EpCAM; notch-like signalling

  • Source: Schnell, U, Kuipers, J & Giepmans, B N G 2013, 'EpCAM proteolysis : new fragments with distinct functions?', Bioscience Reports, vol. 33, e00030, pp. 321-332.

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Academic Journal

EpCAM proteolysis:new fragments with distinct functions?

Subjects: cell-cell contact; EpCAM; notch-like signalling

  • Source: Schnell, U, Kuipers, J & Giepmans, B N G 2013, 'EpCAM proteolysis : new fragments with distinct functions?', Bioscience reports, vol. 33, e00030, pp. 321-332.

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