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Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators

• Authors : Wang, Haiyu; van de Bovenkamp, Fleur S.; Dijkstra, Douwe J.

Subjects: antibobies; autoimmunity; complement

• Source: Wang , H , van de Bovenkamp , F S , Dijkstra , D J , Abendstein , L , Borggreven , N V , Pool , J , Zuijderduijn , R , Gstöttner , C , Gelderman , K A , Damelang , T , Vidarsson , G , Blom , A M ,

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Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

• Authors : Noone, Dylan P.; Isendoorn, Marjolein M.E.; Hamers, Sebastiaan M.W.R.

Subjects: C-Reactive Protein/chemistry; Humans; Phosphorylcholine/chemistry

• Source: Noone , D P , Isendoorn , M M E , Hamers , S M W R , Keizer , M E , Wulffelé , J , van der Velden , T T , Dijkstra , D J , Trouw , L A , Filippov , D V & Sharp , T H 2024 , ' Structural basis for

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Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system

• Authors : Hamers, Sebastiaan M W R; Abendstein, Leoni; Boyle, Aimee L

Subjects: /dk/atira/pure/core/keywords/biodesign_SRI; name=Bristol BioDesign Institute

• Source: Hamers , S M W R , Abendstein , L , Boyle , A L , Jongkees , S A K & Sharp , T H 2024 , ' Selection and characterization of a peptide-based complement modulator

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Engineering Agonistic Bispecifics to Investigate the Influence of Distance on Surface-Mediated Complement Activation

• Authors : Hamers, Sebastiaan M W R; Boyle, Aimee L; Sharp, Thomas H

• Source: Hamers , S M W R , Boyle , A L & Sharp , T H 2024 , ' Engineering Agonistic Bispecifics to Investigate the Influence of Distance on Surface-Mediated Complement

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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

• Authors : Abendstein, Leoni; Noteborn, Willem E.M.; Veenman, Luc S.

• Source: Abendstein , L , Noteborn , W E M , Veenman , L S , Dijkstra , D J , van de Bovenkamp , F S , Trouw , L A & Sharp , T H 2024 , ' DNA Nanostructure-Templated Antibody Complexes Provide Insights into

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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

• Authors : Abendstein, Leoni; Noteborn, Willem E.M.; Veenman, Luc S.

• Source: Abendstein , L , Noteborn , W E M , Veenman , L S , Dijkstra , D J , van de Bovenkamp , F S , Trouw , L A & Sharp , T H 2024 , ' DNA Nanostructure-Templated Antibody Complexes Provide Insights into

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Amyloid-β1-42 oligomers enhance mGlu5R-dependent synaptic weakening via NMDAR activation and complement C5aR1 signaling

• Authors : Ng, Ai Na; Salter, Eric W; Georgiou, John

• Source: Ng , A N , Salter , E W , Georgiou , J , Bortolotto , Z A & Collingridge , G L 2023 , ' Amyloid-β1-42 oligomers enhance mGlu5R-dependent synaptic weakening via NMDAR activation and

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Galaxy And Mass Assembly:the xSAGA galaxy complement in nearby galaxy groups

• Authors : Holwerda, B w; Phillipps, S; Weerasooriya, S

• Source: Holwerda , B W , Phillipps , S , Weerasooriya , S , Bovill , M S , Brough , S , Brown , M J I , Robertson , C & Cook , K 2023 , ' Galaxy And Mass Assembly : the xSAGA galaxy

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Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus

• Authors : Li, Shuxian; Bettoni, Serena; Mohlin, Frida

Subjects: Humans; Complement C4b-Binding Protein; Staphylococcus aureus/genetics

• Source: Li , S , Bettoni , S , Mohlin , F , Geoghegan , J A , Blom , A M & Laabei , M 2023 , ' Recruitment of C4b-binding protein is not a complement evasion strategy employed

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Novel Antibody-independent Method to Measure Complement Deposition on Bacteria

• Authors : Wonfor, Toska; Li, Shuxian; Laabei, Maisem

• Source: Wonfor , T , Li , S & Laabei , M 2023 , ' Novel Antibody-independent Method to Measure Complement Deposition on Bacteria ' , Bio-protocol , vol. 13 , no. 9 , e4671 .

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