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Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators

• Authors : Wang, Haiyu; van de Bovenkamp, Fleur S.; Dijkstra, Douwe J.

Subjects: antibobies; autoimmunity; complement

• Source: Wang , H , van de Bovenkamp , F S , Dijkstra , D J , Abendstein , L , Borggreven , N V , Pool , J , Zuijderduijn , R , Gstöttner , C , Gelderman , K A , Damelang , T , Vidarsson , G , Blom , A M ,

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Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

• Authors : Noone, Dylan P.; Isendoorn, Marjolein M.E.; Hamers, Sebastiaan M.W.R.

Subjects: C-Reactive Protein/chemistry; Humans; Phosphorylcholine/chemistry

• Source: Noone , D P , Isendoorn , M M E , Hamers , S M W R , Keizer , M E , Wulffelé , J , van der Velden , T T , Dijkstra , D J , Trouw , L A , Filippov , D V & Sharp , T H 2024 , ' Structural basis for

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Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus

• Authors : Li, Shuxian; Bettoni, Serena; Mohlin, Frida

Subjects: Humans; Complement C4b-Binding Protein; Staphylococcus aureus/genetics

• Source: Li , S , Bettoni , S , Mohlin , F , Geoghegan , J A , Blom , A M & Laabei , M 2023 , ' Recruitment of C4b-binding protein is not a complement evasion strategy employed

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Clinical Isolates of Acinetobacter spp. Are Highly Serum Resistant Despite Efficient Recognition by the Complement System

• Authors : Magda, Michal; Bettoni, Serena; Laabei, Maisem

Subjects: Acinetobacter/immunology; Blood Bactericidal Activity; Complement Membrane Attack Complex/metabolism

• Source: Magda , M , Bettoni , S , Laabei , M , Fairley , D , Russo , T A , Riesbeck , K & Blom , A M 2022 , ' Clinical Isolates of Acinetobacter spp. Are Highly Serum Resistant Despite Efficient Recognition

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Novel method for detecting complement C3 deposition on Staphylococcus aureus

• Authors : Wonfor, Toska; Li, Shuxian; Dunphy, Rhys W

Subjects: Bacterial Proteins; Biotin/metabolism; Complement C3/metabolism

• Source: Wonfor , T , Li , S , Dunphy , R W , Macpherson , A , van den Elsen , J & Laabei , M 2022 , ' Novel method for detecting complement C3 deposition on Staphylococcus

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Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein

• Authors : Urban, Aleksandra; Kowalska, Daria; Stasiłojć, Grzegorz

Subjects: complement system; aHUS; C3 glomerulopathy

• Source: Urban , A , Kowalska , D , Stasiłojć , G , Kuźniewska , A , Skrobińska , A , Arjona , E , Alonso , E C , Fenollosa Segarra , M Á , Jongerius , I , Spaapen , R , Satchell , S , Thiel , M ,

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Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system

• Authors : Hamers, Sebastiaan M W R; Abendstein, Leoni; Boyle, Aimee L

Subjects: /dk/atira/pure/core/keywords/biodesign_SRI; name=Bristol BioDesign Institute

• Source: Hamers , S M W R , Abendstein , L , Boyle , A L , Jongkees , S A K & Sharp , T H 2024 , ' Selection and characterization of a peptide-based complement modulator

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Engineering Agonistic Bispecifics to Investigate the Influence of Distance on Surface-Mediated Complement Activation

• Authors : Hamers, Sebastiaan M W R; Boyle, Aimee L; Sharp, Thomas H

• Source: Hamers , S M W R , Boyle , A L & Sharp , T H 2024 , ' Engineering Agonistic Bispecifics to Investigate the Influence of Distance on Surface-Mediated Complement

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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

• Authors : Abendstein, Leoni; Noteborn, Willem E.M.; Veenman, Luc S.

• Source: Abendstein , L , Noteborn , W E M , Veenman , L S , Dijkstra , D J , van de Bovenkamp , F S , Trouw , L A & Sharp , T H 2024 , ' DNA Nanostructure-Templated Antibody Complexes Provide Insights into

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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

• Authors : Abendstein, Leoni; Noteborn, Willem E.M.; Veenman, Luc S.

• Source: Abendstein , L , Noteborn , W E M , Veenman , L S , Dijkstra , D J , van de Bovenkamp , F S , Trouw , L A & Sharp , T H 2024 , ' DNA Nanostructure-Templated Antibody Complexes Provide Insights into

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